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    Did you mean Antioxidant Defenses?
    Glossary Antioxidant Defenses

    Antioxidant defenses refer to the body's mechanisms that protect cells from oxidative stress caused by free radicals, which can damage DNA, proteins, and lipids. In the context of hair loss, oxidative stress has been linked to conditions such as androgenetic alopecia and telogen effluvium, where an imbalance between free radicals and antioxidants can lead to hair follicle damage and impaired hair growth. Key distinguishing characteristics of antioxidant defenses include the presence of enzymes like superoxide dismutase and catalase, as well as non-enzymatic antioxidants such as vitamins C and E, which work together to neutralize harmful oxidative agents. Maintaining robust antioxidant defenses is crucial for promoting healthy hair follicles and potentially mitigating hair loss.

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    1. Improvement of Antioxidant Defences in Keratinocytes Grown in Physioxia: Comparison of 2D and 3D Models Oxidative Medicine and Cellular Longevity · 2023 · 9 citations
    2. Nobiletin-loaded composite penetration enhancer vesicles restore the normal miRNA expression and the chief defence antioxidant levels in skin cancer Scientific Reports · 2021 · 34 citations
    3. Mechanisms and applications of the anti-inflammatory effects of photobiomodulation AIMS biophysics · 2017 · 520 citations
    4. Oxidative stress in ageing of hair International Journal of Trichology · 2009 · 126 citations
    5. Selenium or No Selenium- That Is the Question in Tumor Patients: A New Controversy Integrative Cancer Therapies · 2010 · 61 citations
    6. Oxidative stress management in the hair follicle: Could targeting NRF2 counter age‐related hair disorders and beyond? BioEssays · 2017 · 30 citations
    7. Polyphenols rich Hibiscus rosa sinensis Linn. petals modulate diabetic stress signalling pathways in streptozotocin-induced experimental diabetic rats Journal of Functional Foods · 2015 · 11 citations
    8. The Role of Coenzyme Q10 in Skin Aging and Opportunities for Topical Intervention: A Review. PubMed · 2024 · 6 citations
    9. Hair Growth-Promoting Mechanisms of Red Ginseng Extract through Stimulating Dermal Papilla Cell Proliferation and Enhancing Skin Health Journal of Food Science and Nutrition · 2021 · 3 citations
    10. Fermented Morinda citrifolia extract stimulates hair growth by promoting dermal papilla cell proliferation and modulating the follicular microenvironment Journal of Ethnopharmacology · 2026
    11. Correlations between soluble receptor for advanced glycation end products and heme oxogenase-1 in post-COVID-19 patients with telogen effluvium Journal of the Egyptian Womenʼs Dermatologic Society · 2026
    12. Protective effect of a novel metal-phenolic network composite against ultraviolet-induced skin damage by modulating MAPK/AP-1/NF-κB signaling pathways and attenuating oxidative stress in human keratinocytes Biomedicine & Pharmacotherapy · 2025
    13. Structural and Pigmentary Characteristics of the Skin in Hairless Dog Breeds International Journal of Advanced Multidisciplinary Research and Studies · 2025
    14. 4-hydroxynonenal, a lipid peroxidation product, inhibits glutathione peroxidase: Protective effect of glutathione Pathophysiology · 1998
    15. Beyond Circadian Rhythm: Melatonin as a Bio-Regulatory Molecule in Skin and Hair Aesthetics International Journal of Science and Research (IJSR) · 2026
    16. Protective Effects of Schinus terebinthifolius Leaf Supercritical Fluid Extract Against UVC-Induced Oxidative Stress: A Com-Prehensive Gene Expression Study International Journal of Molecular Sciences · 2026
    17. Herbal Approaches for the Management of Premature Hair Greying: Mechanisms, Phytoconstituents and Delivery Strategies International Journal of Drug Delivery Technology · 2026
    18. Targeting ferroptosis in photoaging: mechanisms and therapeutic potential of adipose-derived stem cell exosomes Plastic and Aesthetic Research · 2026
    19. Deciphering the Skin Anti-Aging and Hair Growth Promoting Mechanisms of Opophytum forskahlii Seed Oil via Network Pharmacology International Journal of Molecular Sciences · 2025
    20. Hair Growth and Health Promoting Effects of Standardized Ageratum conyzoides Extract in Human Follicle Dermal Papilla Cells and in C57BL/6 Mice Nutrients · 2025
    21. Integrated experimental and computational evaluation of the wound-healing potential of Fraxinus xanthoxyloides bark extract Scientific Reports · 2026
    22. Protective effects of wheat sprouts extract against acrylamide-induced skin toxicity: Modulation of oxidative stress, apoptosis, and histomorphometric alterations in rats Environmental Science and Pollution Research · 2026
    23. Hepatoprotective and anti-hyperplastic effects of silver nanoparticles biosynthesised using aqueous extracts of Springer Link (Chiba Institute of Technology) · 2026
    24. Hepatoprotective and anti-hyperplastic effects of silver nanoparticles biosynthesised using aqueous extracts of <i>M. scaber</i> : Insights from acetaminophen and testosterone experimental models E3S Web of Conferences · 2026
    25. 030 Impaired Glutathione Synthesis in Hair Follicle Stem Cell Niches in Alopecia Areata Journal of Investigative Dermatology · 2025
    26. The Gut-Scalp Axis: A Systematic Review of Dietary Interventions on Microbiome Dysbiosis in Scalp Disorders Journal of Pioneering Medical Science · 2025
    27. Intermittent Fasting and Skin Health: Molecular Mechanisms and Clinical Implications International Journal of Advanced Pharmaceutical Sciences and Research · 2025
    28. Decision letter: Quantitative mapping of human hair greying and reversal in relation to life stress 2021
    29. Zinc: A complementary factor in the treatment of chronic hepatitis C? (Review) Molecular Medicine Reports · 2010 · 21 citations
    30. Effect of nutrient antioxidants on oxidative stress indicators in patients with alopecia areata 2007 · 1 citations