1 citations
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December 2005 in “Therapeutische Umschau” This article reviews anti-aging strategies in dermatology, emphasizing the role of skin as a model for studying aging and promoting preventive and therapeutic interventions, but it does not present new findings.
6 citations
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August 2019 in “PLOS ONE” The researchers reported that Gambogic Amide may prevent hair greying and promote hair growth by maintaining follicle pigmentation in vitro through activation and migration of melanocytes.
1 citations
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September 2013 in “Elsevier eBooks” This review discusses factors affecting hair aging, such as inflammation and UV exposure, and examines potential anti-aging benefits of antioxidants and nutraceuticals for hair, but reports no new clinical results.
This study explored the potential of custard apple extract in an herbal hair conditioner to improve smoothness, aid brushing, and provide other cosmetic benefits, including lice removal and anti-aging effects.
25 citations
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March 2012 in “Journal of oncology pharmacy practice” This case report describes an elderly multiple myeloma patient whose hair repigmentation was associated with lenalidomide use, suggesting hair graying may be reversible.
99 citations
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June 2005 in “Journal of Cosmetic Dermatology” This article reviews factors influencing hair aging and available treatments like minoxidil and finasteride for androgenetic alopecia but reports no new clinical results.
August 2023 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Minoxidil users may experience hair discoloration, especially with long-term use and a family history of gray hair.
This review highlights Neelibhringadi Hair Oil as a traditional Ayurvedic option for managing hair issues like dandruff and thinning, supported by its antioxidant and anti-inflammatory properties, but emphasizes the need for modern clinical trials to confirm its effectiveness.
3 citations
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January 2022 in “Journal of drugs in dermatology” This review of literature and market analysis found that rice bran extracts may promote hair growth through molecular mechanisms while being safe for cosmetic use, though further research is warranted.
1 citations
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May 2009 in “Annales de Dermatologie et de Vénéréologie” This article reviews environmental factors contributing to androgenic alopecia and emphasizes the importance of giving patients advice to manage hair loss; it reports no new clinical findings.
4 citations
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August 2018 in “Journal of cellular biochemistry” This study found that sustained intracellular acidosis in mice was associated with shortened lifespan, early aging signs, and impaired autophagy.
2 citations
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October 2022 in “International journal of Ayurvedic medicine” This review examines the traditional uses and biological activities of Glycyrrhiza glabra in Ayurveda, but reports no new clinical results; the authors identify a gap in evidence supporting its medicinal potential.
15 citations
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January 2017 in “Pigment International” This article reviews the pathogenesis and treatment approaches for premature graying of hair, noting the unsatisfactory options currently available, and reports no new clinical findings.
In this observational study, researchers found that post-COVID-19 patients with telogen effluvium experienced varying hair loss and quality of life impacts, but no clear link was observed between this hair loss and vitamin D levels or quality of life.
January 2019 in “Research Square (Research Square)” In this study, researchers will conduct a randomized, double-blind, multi-center clinical trial to assess the effectiveness of YH0618 granule in preventing chemotherapy-induced hair loss among breast cancer patients, aiming to understand its mechanism related to kidney deficiency in Chinese Medicine. Results are not yet reported.
7 citations
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March 1990 in “Pigment Cell Research” This animal study observed that while topical MBEH and intraperitoneal phenol induced hair graying in eumelanic mice, they had little effect on pheomelanic mice, and amcinonide reduced certain epidermal melanocytes in both.
January 2024 in “Academic Journal of Medicine & Health Sciences” This study highlights a novel herbal tea blend that may improve hair health and provide anti-aging benefits, though its efficacy requires further scientific validation.
56 citations
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November 2010 in “Pigment Cell & Melanoma Research” This article discusses the role of neurohormones and neuropeptides in hair follicle pigmentation and outlines promising neuroendocrinological strategies to address greying and damage, but reports no new clinical results.
78 citations
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September 2008 in “International Journal of Cosmetic Science” This review outlines various clinical methods for assessing ageing skin and discusses their application in supporting the efficacy claims of anti-ageing treatments, but it reports no new clinical results.
5 citations
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August 2019 in “iScience” In this study, Trf1 genetic deletion in mice, including those with cancer-prone mutations, was shown to not affect overall viability and cause only mild effects, while being necessary for tumor formation, suggesting a potential therapeutic window for Trf1 as an anti-cancer target.
February 2025 in “International Journal of Molecular Sciences” In this study, researchers identified significant differences in lipid composition between grey and black hair follicles in women with type 2 diabetes and healthy controls, suggesting these lipids may contribute to the production of grey hair and may offer targets for anti-grey-hair treatments.
June 2024 in “British Journal of Dermatology” In this case report, an 80-year-old woman experienced darkening of previously grey hair, which may be linked to vitamin B supplementation, though its effectiveness is typically associated with reversing greying only in the presence of an initial vitamin B deficiency.
This source highlights Amla's potential as a natural remedy due to its high vitamin C, fiber, iron, and antioxidant content, marking its benefits in slowing aging, enhancing hair and skin health, managing diabetes, and exhibiting anticancer, antioxidant, and immunomodulatory effects.
April 2025 in “International Journal of Ayurveda and Pharma Research” This case study described the use of Ayurvedic treatments, including internal medications and external applications, which resulted in black hair growth, increased hair density, and reduced hair fall in a 28-year-old woman with premature graying.
36 citations
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September 2011 in “British Journal of Dermatology” This study found that white hair exhibits increased expression of genes and proteins linked to active hair growth compared to black hair, suggesting that hair greying is associated with enhanced hair growth activity.
January 2026 in “Stem Cell Reviews and Reports” Hair graying may help prevent cancer by protecting stem cells.
January 2026 in “International Journal of Science and Research Methodology” This review explored the therapeutic potential of Bhangra (Eclipta alba) for treating premature greying of hair, noting the plant's melanogenic, antioxidant, and revitalizing properties, but highlighted the need for further research to scientifically support its effectiveness.
1 citations
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September 2024 in “Quality in Sport” This review explores the complex biological process of hair graying, highlighting oxidative stress, genetic factors, and interventions like antioxidants and genetic therapy as key aspects affecting the preservation of hair pigmentation.
February 2026 in “Chinese Medicine” Natural products might help treat hair greying.
47 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This review examines the pathogenesis of premature hair graying and potential treatment avenues, but reports no new experimental outcomes, highlighting ongoing research challenges and hopes for drug development.