35 citations
,
August 2010 in “The American journal of pathology” This study reports that hypomorphic alleles of the Ass1 gene in mice resemble human CTLN1, providing a potential model for preclinical studies and indicating that standard treatments for CTLN1 can rescue phenotypes.
10 citations
,
June 2024 in “Frontiers in Genetics” This study analyzed RNA-seq data from various animal breeds and suggested that similar molecular mechanisms may underlie wool fineness in different sheep breeds. Researchers identified 32 candidate genes related to hair follicle regulation, providing insights for molecular breeding and evolutionary studies.
4 citations
,
November 2025 in “Molecules” This review reports that cerium oxide nanoparticles may accelerate wound healing in animal models, but further standardized and comparative studies are needed to confirm their potential for clinical applications.
15 citations
,
March 2023 in “Heliyon” This study found that water-soluble beehive extract exhibited anxiolytic, antidepressant, and anti-inflammatory effects in animal models.
2 citations
,
December 2024 in “International Journal of Pharmaceutics” In animal studies, this research found that minoxidil-loaded air-pocket microneedles improved hair loss treatment efficiency compared to topical application, while effectively sealing punctured skin openings.
38 citations
,
July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
October 2014 in “Springer eBooks” Rabbit hair fibers are similar to wool and have a hollow center like feathers.
1 citations
,
December 2019 in “Formuly farmacii” This article reviews the complex etiology of alopecia and emphasizes the need for detailed pathogenesis studies in animal models to develop effective personalized treatments, without presenting new experimental data.
40 citations
,
January 1985 in “Tissue and Cell” This study found that sebum in sebaceous glands is produced from cell populations derived from peripheral progenitor cells, similarly to hair growth, without direct involvement from other peripheral cells.
11 citations
,
March 2001 in “Clinics in dermatology” This study found that using a novel dissolving microneedle with valproic acid effectively enhances hair follicle regrowth through improved delivery and activation of the Wnt/β-catenin pathway compared to topical application.
1 citations
,
March 2021 in “Skin health and disease” This review evaluates laboratory models used in androgenetic alopecia research but reports no new findings, emphasizing the potential of human-derived 3-D models for future studies.
March 2023 in “Aktualʹnì pitannâ farmacevtičnoï ì medičnoï nauki ta praktiki” This study found that a 2% minoxidil cream and a gel-based shampoo with 1% minoxidil plus plant extracts showed significant hair growth and follicle-protective effects in laboratory rats with experimental alopecia.
18 citations
,
April 2009 in “Journal of Chromatography A” Detecting steroid esters in cattle hair is inconsistent and influenced by sampling factors.
30 citations
,
May 1999 in “Food and chemical toxicology” This study suggests that topical procyanidin B-2 is safe for use as a hair growth agent, as it showed no mutagenic effects or significant irritation in a series of toxicological tests.
9 citations
,
January 2003 in “Organic Eprints (International Centre for Research in Organic Food Systems, and Research Institute of Organic Agriculture)” This research observed that while organic farming systems in Southern Norway showed decreased phosphorus over time and variable nitrogen retention, the mulching of plant material could enhance vegetable yields, suggesting a need for innovative nutrient management strategies in organic farming.
January 2012 in “TRANSACTIONS OF THE JAPAN SOCIETY FOR AERONAUTICAL AND SPACE SCIENCES AEROSPACE TECHNOLOGY JAPAN” This paper outlines the research plan and current progress of a study analyzing mineral metabolism changes in astronauts by examining hair shafts after long-term space flight, with no new results yet.
September 2008 in “Fertility and Sterility” This study found that in female dogs, exposure to free fatty acids increased androgen production, suggesting a potential link to factors characteristic of polycystic ovary syndrome.
January 1972 in “Open PRAIRIE (South Dakota State University)” This research explored potential mechanisms for the toxicity of mimosine but did not identify a conclusive reason for its adverse effects.
4 citations
,
December 2021 in “Journal of Pharmacopuncture” This study reports that the microneedle therapy system has demonstrated significant effects on acne, acne scars, and hair loss treatment without serious side effects in Korean studies over the past decade.
December 2021 in “International Journal of Medicine in Developing Countries” This review examined existing studies on topical finasteride for androgenetic alopecia and noted inconsistent application of hair evaluation methods, suggesting a need for standardization in future research.
3 citations
,
September 1989 in “Journal of Investigative Dermatology” This study found that methyl nonanoate and methyl caprate significantly enhanced the skin penetration of minoxidil compared to solutions with other common enhancers like Azone, DMSO, or DEET.
July 2025 in “Frontiers in Animal Science” This editorial discusses the need for continued research on animal fibers, highlighting recent advances in the field and the impact of economic factors favoring meat over fiber production on research volume.
11 citations
,
March 1959 in “Journal of Histochemistry & Cytochemistry” This study observed that radioactive sulphur appeared in rat and mouse hair follicles more quickly than in lambs, possibly linked to faster hair growth rates in the rodents.
21 citations
,
August 2024 in “Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology” This paper reviews the advancements and applications of single-cell transcriptomics in animal research, highlighting its potential to enhance understanding of animal nutrition, health, genetics, and disease models.
1 citations
,
March 1954 in “Archives of dermatology” This article reviews small animal experiments reported from 1932 to 1952 in two dermatology journals and notes the contributions of Farris's book on laboratory animal care.
59 citations
,
February 2003 in “Veterinary Dermatology” This narrative review discusses the use of cyclosporin for various skin diseases in small animals and notes minimal side effects at therapeutic doses, but reports no original clinical findings.
28 citations
,
January 2000 in “Medical Mycology” This article reviews the impact of natural fungal pathogens on laboratory animal research and reports no new results, calling attention to infection risks with dermatophytes, Candida, and pneumonia in immunocompromised rodents.
2 citations
,
December 1988 in “PubMed” This study concluded that there was clear evidence of carcinogenic activity of C.I. Acid Orange 3 in female F344/N rats but not in male rats or B6C3F1 mice of either sex.
April 2024 in “Frontiers in endocrinology (Lausanne)” In this meta-analysis, researchers found that melatonin did not affect primary hair follicles or litter size in goats but was positively correlated with secondary follicle growth, suggesting potential relevance for studying hair growth mechanisms and human alopecia.
February 2024 in “Oriental Journal of Chemistry/Oriental journal of chemistry” This review reports various ethnomedicinal uses, phytochemical components, and potential pharmacological effects of Eclipta alba, highlighting benefits like wound healing and neuroprotection, though it underscores the need for further mechanism-based studies and clinical trials.