11 citations
,
December 2024 in “Wound Repair and Regeneration” In this study, researchers created the WRAHPS Guidelines to standardize the reporting of preclinical wound healing studies, aiming to improve transparency, enable comparative analysis, and support the development of human clinical trials for wound healing disorders.
June 2023 in “Livestock studies” This review highlights the significance of animal fibers, examining the molecular mechanisms influencing hair follicle development and their impact on fiber quality and quantity, with a focus on studies involving Angora and cashmere goats.
5 citations
,
September 2006 in “Natural medicines/Journal of natural medicines” Microscopic hair features can identify different Cauda Cervi species.
1 citations
,
February 2018 in “Madridge journal of dermatology & research” In this study, Satura® Rosta remedy was found to significantly increase hair follicle size, hair root volume, and skin thickness in mice, potentially by prolonging the anagen phase, with notable hair regrowth observed in older mice with alopecia.
February 2024 in “Neurophotonics” This review highlights the potential of transcranial photobiomodulation (tPBM) as a non-invasive and affordable treatment for brain diseases, summarizing recent advances and successful protocols based on over two decades of research.
8 citations
,
June 2025 in “Stem Cell Research & Therapy” This review discusses the potential of exosome therapy for treating diabetic peripheral neuropathy but highlights the need for more robust preclinical trials before clinical application.
85 citations
,
January 1996 in “International Journal of Cancer” In this study, AS101 combined with chemotherapy significantly reduced the severity of chemotherapy-induced alopecia in non-small-cell-lung-cancer patients and may involve immune mechanisms related to IL-1 and PGE2.
January 2022 in “World journal of pharmaceutical sciences” This review discusses methods for inducing polycystic ovary syndrome in animal models, with letrozole considered the easiest and most convenient for testing new treatments, but it reports no new clinical findings.
June 2026 in “Functional Foods in Health and Disease” This study found that water extract of olive leaf may enhance markers linked to epidermal and dermal stem cell activity and potentially improve skin aging, especially in individuals who do not exercise regularly.
35 citations
,
August 2016 in “Experimental Dermatology” This viewpoint essay discusses the potential of fullerene C60 derivatives as novel treatment agents in dermatology, highlighting their ability to act as both radical scavengers and oxygen radical generators.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses follicular cell implantation as a potential solution for hair restoration limitations, but notes inconsistencies and challenges in human applications, reporting no new clinical results.
6 citations
,
May 2011 in “Pharmacognosy Journal” This review discusses the causes of alopecia, including androgenetic alopecia, and potential active ingredients for hair regrowth, but it does not report new clinical results.
April 2026 in “Asian Journal of Research in Pharmaceutical Sciences” This review highlights the promising potential of Semecarpus anacardium Linn. in promoting hair growth due to its antioxidant and anti-inflammatory properties but emphasizes the need for further human clinical trials and safe formulation practices due to its associated toxicity in raw form.
41 citations
,
July 2015 in “Current Drug Discovery Technologies” This review discusses various plants and herbal formulations traditionally used for hair growth and notes their potential as safer alternatives to synthetic hair loss treatments, but reports no new clinical results.
36 citations
,
July 1980 in “Journal of Toxicology and Environmental Health” In this animal study, rats given high doses of ethynylestradiol showed dose-related estrogenic effects, delayed tumor onset in females, and no overall increase in tumor incidence compared to controls.
February 2025 in “International Journal of Molecular Sciences” This meta-analysis of animal studies found that alkaloids have potential anti-influenza and anti-inflammatory effects, correlating with improved viral titers and survival rates, though they did not effectively reduce TNF-α and IL-6 levels. Extensive further studies are needed to confirm these findings before considering clinical application.
9 citations
,
January 1989 in “Sen'i Gakkaishi” This study found that moisture sorption properties of wool and hair fibers from various animals were similar, despite different structural features, with sorbed water being more ordered than liquid water.
43 citations
,
January 1977 in “Toxicology and Applied Pharmacology” In this study, minoxidil was found to have low toxicity in various animals, with specific heart lesions observed only in dogs at certain doses.
149 citations
,
September 2017 in “Pharmaceutics” This review compares animal and human skin characteristics in in vitro permeation studies but reports no new results, highlighting variations and the need for better model correlations.
4 citations
,
September 2004 in “Experimental Dermatology” This article reviews the role of epidermal proteins and their complex gene families in maintaining skin integrity and highlights insights gained from genetic studies and mouse models, without providing new clinical results.
28 citations
,
August 2015 in “Journal of Drug Targeting” This study found that a novel proniosomal gel formulation of CoQ10 improved antioxidant levels and provided better skin protection against UV radiation compared to a conventional CoQ10 gel in animal models.
5 citations
,
January 2000 in “Inhalation Toxicology” This study found that exposure to aqueous dispersion resin in aerosol form increased lung weights and caused histopathological changes in animals at higher concentrations, with a no-observable-effect level at 30 mg/m³.
December 2025 in “Current Issues in Molecular Biology” In this systematic review, animal studies showed that cytarabine causes multi-organ toxicities, notably neurotoxicity, linked to oxidative stress and other mechanisms, though study quality raises concerns about reliability and translation to human outcomes.
November 2024 in “Journal of Investigative Dermatology” Microfluidic models improve testing for aging, wound healing, and oral tissue, reducing animal testing.
104 citations
,
January 2016 in “Food & Function” This review found that olive oil phenols may have anti-cancer properties in animal models and some human studies, but further research is needed to confirm these effects in humans.
June 2026 in “Journal of Materials Science Materials in Medicine” This study explored nanoemulsions of minoxidil, revealing that a 5% minoxidil nanoemulsion improved hair growth and follicle count in animal studies compared to commercial minoxidil solutions, even without significant differences in permeation rates.
17 citations
,
October 2015 in “Medicine and Pharmacy Reports” This article reviews current research on animal models for hair regrowth treatments and reports no new findings; it highlights the need for studies comparing therapy efficiency and long-term safety.
21 citations
,
August 2020 in “Stem Cell Research & Therapy” This meta-analysis suggests that stem cell therapy may reduce burn wound area and improve healing-related factors in preclinical models, indicating potential for future clinical studies on burn treatment.
15 citations
,
July 2020 in “Stem Cell Research & Therapy” This study found that stem cell therapy significantly improved burn healing rates in animal models, with hair follicle stem cells showing particularly strong effects.
5 citations
,
February 2022 in “International Journal of Molecular Sciences” This review discusses the roles of distinct immune cell types in skin wound healing, highlighting findings from animal studies, but provides no new clinical results.