December 2025 in “IP Indian Journal of Clinical and Experimental Dermatology” This study found that androgenetic alopecia in men is associated with significant psychological distress and moderate depression, suggesting a possible link between raised dihydrotestosterone levels and mental health issues.
30 citations
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March 2015 in “Journal of Dermatology” This study found that certain trichoscopic features like white peripilar sign, yellow dots, and scalp pigmentation are positively correlated with the severity of androgenetic alopecia in Chinese patients.
30 citations
,
January 2014 in “Annals of Dermatology” This study observed no significant relationship between trichoscopic findings and disease severity in male or female androgenetic alopecia, despite some specific patterns correlating with different severity levels in female patients.
12 citations
,
January 2019 in “International Journal of Trichology” This study found that trichoscopy revealed significant differences in certain variables, such as the brown peripilar sign and white peripilar sign, which may aid in diagnosing early and late stages of androgenetic alopecia.
June 2021 in “The American Journal of the Medical Sciences” This study found that patients with androgenetic alopecia had higher serum homocysteine levels, linked to the mutant MTHFR genotype, and an increased risk of coronary heart disease.
July 2025 in “YAKUGAKU ZASSHI” This review highlights that dysbiosis in skin and scalp microbiomes is linked to both atopic dermatitis and androgenetic alopecia, suggesting that microbial composition influences disease progression.
July 2023 in “International journal of trichology” In this study, no significant association was found between the severity of androgenetic alopecia in males and trichoscopy features such as hair diameter diversity, vellus hair, and white dots, suggesting that trichoscopy may not predict alopecia severity based on the Hamilton–Norwood scale.
November 2025 in “Skin Appendage Disorders” In this retrospective cohort study, researchers found that male patients with androgenetic alopecia had significantly lower risks of developing abdominal obesity, dyslipidemia, hypertension, and diabetes mellitus compared to matched controls, suggesting behavioral rather than biological factors may contribute to these outcomes.
December 2022 in “Pakistan Armed Forces Medical Journal” This study suggests that a high frequency of androgenetic alopecia is associated with increased severity of COVID-19 in hospitalized patients.
October 2021 in “QJM: An International Journal of Medicine” This study concluded that smoking, stress, obesity, family history, exercise, hypertension, and unbalanced diet are significant non-genetic factors associated with androgenetic alopecia in Egyptian males.
87 citations
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May 2012 in “PLOS Genetics” This study found that early-onset androgenetic alopecia in individuals of European ancestry is significantly associated with increased odds of Parkinson's disease and is influenced by specific genetic loci, including some linked to reduced fertility.
25 citations
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June 2019 in “Endocrine Related Cancer” This review discusses the structure and function of steroid nuclear receptors, particularly focusing on androgen receptor dysregulation in prostate cancer and androgen insensitivity syndromes, without reporting new experimental results.
October 2024 in “World Journal of Psychiatry” In this study, patients with androgenetic alopecia experiencing stress had higher cortisol levels and altered neurotrophic factors compared to non-stressed patients, which correlated with more severe hair loss progression even after minoxidil treatment.
November 2008 in “Central Plains Medical Journal” This study found that combining zinc with topical minoxidil significantly improved curative rates in treating androgenetic alopecia after 9 and 12 months compared to zinc alone.
August 2019 in “Journal of The American Academy of Dermatology” PFD patch helps laser tattoo removal, trichoscopy diagnoses AGA, and serum boosts SOD activity.
August 2007 in “Pajoohandeh Journal” Men with baldness may have a higher risk of heart disease.
October 2024 in “Archives of Dermatological Research” The study found that patients with androgenetic alopecia had higher serum GPER-1 levels, which were associated with disease severity and duration, indicating a potential estrogen-independent role of GPER-1 in the condition's pathogenesis.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
October 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Six new genes linked to early hair loss were found, which also surprisingly connect to Parkinson's disease and lower fertility.
January 2022 in “Voennaâ medicina” This case study describes a successful treatment of androgenetic alopecia in a 34-year-old man through a comprehensive program involving low-dose minoxidil, without finasteride, resulting in significant hair growth improvements.
3 citations
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October 1995 in “International Journal of Dermatology” This study confirms that finasteride inhibits the conversion of testosterone to dihydrotestosterone in human dermal fibroblasts, suggesting potential therapeutic use for androgen-related skin disorders.
343 citations
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October 2015 in “Endocrine Practice” This review discusses the diagnostic criteria and management strategies for Polycystic Ovary Syndrome (PCOS) and highlights the need for comprehensive clinical assessment, but does not report new clinical findings.
September 2009 in “Hair transplant forum international” This article reports that the ISHRS has formed a committee to register hair restoration outcomes in patients with cicatricial alopecia and other hair diseases, without presenting new research findings.
March 2024 in “Actas Dermo-Sifiliográficas”
139 citations
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December 2020 in “Cell Stem Cell” Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.
121 citations
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November 2020 in “Endocrine” This review discusses evidence on androgen sensitivity as a potential factor in COVID-19 disease severity, suggesting that androgen receptor interactions could influence virus entry and progression, and reports no new clinical results.
99 citations
,
June 1999 in “The Journal of Clinical Endocrinology and Metabolism” This commentary discusses the potential use of testosterone therapy for various conditions in women and reports no new clinical results; the authors advocate for more discussion and research in this area.
52 citations
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February 2018 in “Diabetology & Metabolic Syndrome” This review discusses the association between various skin conditions and metabolic syndrome, reporting no new clinical results but suggesting a potential reciprocal relationship that warrants further investigation.
37 citations
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January 2010 in “Acta dermato-venereologica” This study found that both men and women with androgenic alopecia had significantly higher triglycerides, total cholesterol, and LDL-C and lower HDL-C levels than controls, suggesting increased dyslipidemia prevalence.
34 citations
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January 2014 in “Indian Dermatology Online Journal” This study supports evaluating metabolic syndrome and insulin resistance in young males with advanced androgenic alopecia to potentially reduce future cardiovascular and type 2 diabetes risks.