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Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.

The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.

Female and male AGA are different diseases.

AGA in children needs careful diagnosis due to low androgen levels and possible other causes.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

Some skin conditions are associated with other serious diseases, and office microscopy may miss many fungal infections.

Hair loss can indicate underlying systemic diseases and addressing these can sometimes reverse the hair loss.

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

A thorough history and examination are crucial for diagnosing skin diseases, which affect up to a third of people. This includes details about skin lesions, medication, general health, lifestyle, family, and contacts, as well as examining the rash, hair, nails, and mucous membranes. Changes in hair and nails can also indicate other medical and skin disorders.

Men with male-pattern baldness have higher levels of certain testosterone metabolites and may have more active androgen metabolism.

FGF signaling is a promising target for developing treatments for wounds, metabolic diseases, and cancer.

Cyproterone acetate is used to treat conditions like prostate cancer, early puberty, excessive sexual drive, and female androgenization by affecting androgen functions and suppressing certain hormones.

The document concludes that proper diagnosis and combined treatments are key for hirsutism management, and weight loss may help overweight patients.

Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.

ERG increases SOX9, promoting prostate cancer growth and invasion.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Hair loss needs more research for better treatments.

Male hormones like testosterone may make COVID-19 worse, and testing for sensitivity to these hormones could help predict how severe a patient's symptoms might be. Treatments that reduce these hormones are being explored.

Two enzymes regulate androgen receptor activity, affecting treatments for androgen insufficiency and benign prostatic hyperplasia.

Hormones might affect the skin condition hidradenitis suppurativa, but their exact role is unclear.

Steroidogenic isoenzymes may help improve treatments for common hair loss.

Most hirsutism cases are due to PCOS, and treatment focuses on lowering testosterone and blocking its effects.

Advancements in male reproductive medicine are ongoing, but more research and improved treatments are needed in several areas.

The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Antiandrogens are the main treatment for hirsutism, with individualized care and safe, affordable options needed.

A new treatment called SAMiRNA-AR68 increases hair count in people with hair loss, showing similar results to existing treatments but without side effects.