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New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Finasteride and dutasteride reduce neurosteroid production, possibly helping treat glioblastoma.

Prostate-specific antigen may be a new marker for excess male hormones in women with polycystic ovary syndrome.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Certain gene variants may contribute to high androgen levels in women with polycystic ovary syndrome.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

Cytokines and neuropeptides are key in controlling androgen levels, affecting skin and hair conditions.

The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.

Testosterone therapy helps boys with hormone deficiencies develop normal male characteristics and grow properly.

Metformin works better for adolescent girls with PCOS who have certain genetic variations.

The document concludes that a systematic approach is crucial to identify causes of androgen excess in women beyond the most common cause, Polycystic ovary syndrome (PCOS).

AGA in children needs careful diagnosis due to low androgen levels and possible other causes.

Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.

Two women with very high androgen levels had only slight skin issues, one due to a non-classical adrenal disorder and the other due to an adrenal tumor.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Birth control pills and anti-androgen medications help manage hair growth, acne, and hair loss in women with PCOS.

Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

Insulin resistance and high male hormone levels are major causes of Polycystic Ovary Syndrome.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Current research explores hair growth drugs, while future research aims for personalized treatments.

Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.

Spironolactone is a safe and effective treatment for reducing excessive hair growth in women.

Androgens can help prevent memory problems caused by apoE4.

Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.

Mice with human gene experienced hair loss when treated with DHT.

Men with testicular cancer were less likely to experience baldness and severe acne.

The document suggests that blocking sweat glands with antiperspirants might allow skin-generated hormones to be absorbed, possibly increasing breast and prostate cancer risk.

Sebaceous glands in our skin, developing during pregnancy and active in puberty, produce sebum for skin lubrication, temperature control, and fighting germs, also help in hormone regulation, and their dysfunction can cause conditions like acne and hair loss.