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Androgens and SARMs play a role in body mass, frailty, skin health, and hair growth, and are used in treating prostate cancer, acne, and hair loss, with potential for new uses and improved versions in the future.

The compound (1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile can stimulate hair growth and reduce oil production when applied topically.

Scientists made a chemical (compound 4e) that can be applied on skin to reduce oil production, which can help with acne, but it might cause skin sensitivity to light.

Compound 15a was effective in inhibiting 5α-reductase.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

Certain Dibenzo derivatives may help treat prostate cancer.

Women with congenital adrenal hyperplasia (CAH) have more sexual function issues than those with polycystic ovary syndrome (PCOS), but physical activity can improve sexual functioning in all women.

Anti-androgens are effective for female acne but less so for male-pattern hair loss, with side effects similar to birth control pills.

A new, less toxic and more efficient method to create the anti-baldness compound RU58841 was developed in 2014.

Androgens and androgen receptors are important for metabolic health, affecting how the body uses glucose and fats through mitochondrial function.

The authors maintain that shorter androgen receptor alleles may lead to milder COVID-19 by positively affecting the immune response, not due to changes in testosterone levels or activity.

Androgens like testosterone affect skin health and can lead to conditions such as acne and hair loss, with various treatments available.

Combining RU58841 and minoxidil significantly increases hair growth.

The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

MK-0773 safely increased muscle mass but did not improve muscle strength or function in elderly women with sarcopenia.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Male pattern baldness involves hormones and cell signals affecting hair growth.

Androgens block hair growth by disrupting cell signals; targeting GSK-3 may help treat hair loss.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

A three-month treatment with a GnRH agonist significantly lowered androgen levels and 5α-reductase activity in men with benign prostatic hyperplasia.

A new gene, JMJD1C, may affect testosterone levels in men.

Androgens are important for normal ovarian function and estrogen production, but may not be the main cause of follicle death.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Use "female pattern hair loss" term, assess androgen excess, treat with minoxidil and other medications if needed.

Dietary changes, including weight loss and a balanced diet, are important for managing PCOS, especially in overweight women.

Androgen receptor activity blocks Wnt/β-catenin signaling, affecting hair growth and skin cell balance.

Women with androgen excess, especially those with PCOS, have a much higher risk of heart disease and stroke.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

Blocking the androgen receptor in skin cells reduces their growth response to male hormones, suggesting a possible treatment for skin conditions linked to androgens.