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    Glossary Androgen Activity

    effects of male sex hormones on body tissues

    Androgen activity refers to the effects that androgens, which are male sex hormones like testosterone, have on the body. These hormones bind to specific receptors in various tissues, influencing characteristics such as hair growth, muscle mass, and the development of male secondary sexual characteristics. In the context of hair, increased androgen activity can lead to conditions like androgenic alopecia, commonly known as male or female pattern baldness.

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    1. Identification of A p300–SP1–BRD4 Transcriptional Axis as a Key Driver of AR Hyperactivation in Polycystic Ovarian Syndrome Advanced Science · 2026
    2. Foreword American Journal of Clinical Dermatology · 2011
    3. Becker's Nevus Syndrome Journal of pediatric neurology · 2018 · 4 citations
    4. Hair cortisol in polycystic ovary syndrome Scientific reports · 2022 · 2 citations
    5. The Glucocorticoid Resistance Syndrome. Two Cases of a Novel Pathogenic Variant in the Glucocorticoid Receptor Gene JCEM case reports · 2023
    6. [Hirsutism]. PubMed · 1993
    7. Cutaneous Androgen Metabolism: Basic Research and Clinical Perspectives 2002 · 233 citations
    8. Dermatology of androgen-related disorders Clinics in Dermatology · 2006 · 67 citations
    9. Analysis of androgen receptor expression and activity in the mouse brain Scientific Reports · 2024
    10. Hair Loss and Androgen’s Role in the Era of COVID-19 International Journal of Biomedicine · 2022
    11. Alopecia areata – hyperactivity of the hypothalamic–pituitary–adrenal axis is a myth? Journal of the European Academy of Dermatology and Venereology · 2017 · 5 citations
    12. Is seborrhea a sign of autonomic impairment in Parkinson's disease? Journal of Neural Transmission · 1997 · 46 citations
    13. Is COVID-19 a risk factor for progression of benign prostatic hyperplasia and exacerbation of its related symptoms?: a systematic review Prostate Cancer and Prostatic Diseases · 2021 · 21 citations
    14. Green Tea Extract: A Novel Addition to the Antihirsutism Armamentarium? 2009 · 3 citations
    15. BRIDGING THE GAP IN ACNE MANAGEMENT: A NARRATIVE REVIEW OF CURRENT THERAPIES AND THE EMERGENCE OF CLASCOTERONE International Journal of Innovative Technologies in Social Science · 2026
    16. Antioxidant enzyme expression of mRNA and protein in the epididymis of finasteride-treated male rat offspring during postnatal development Archives of Medical Science · 2017 · 2 citations
    17. Allosteric interactions prime androgen receptor dimerization and activation bioRxiv (Cold Spring Harbor Laboratory) · 2022 · 1 citations
    18. From gene to therapy in spinal and bulbar muscular atrophy: Are we there yet? Molecular and Cellular Endocrinology · 2017 · 17 citations
    19. Polycystic ovary syndrome The Lancet · 2007 · 989 citations
    20. Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth International journal of reproductive medicine · 2014 · 222 citations
    21. Sex differences in the hypothalamic–pituitary–adrenal axis’ response to stress: an important role for gonadal hormones Neuropsychopharmacology · 2019 · 197 citations
    22. Endocrine control of benign prostatic hyperplasia Andrology · 2016 · 97 citations
    23. Hormonal therapy for acne: why not as first line therapy? facts and controversies Clinics in Dermatology · 2009 · 76 citations
    24. MENSTRUAL DISORDERS IN ADOLESCENTS Pediatric Clinics of North America · 1999 · 75 citations
    25. Comparison of cyproterone acetate plus ethinyl estradiol and finasteride in the treatment of hirsutism Journal of Endocrinological Investigation · 1998 · 49 citations
    26. Hormonal treatment of acne vulgaris: an update Clinical, Cosmetic and Investigational Dermatology · 2016 · 46 citations
    27. Steroid Sulfatase Deficiency and Androgen Activation Before and After Puberty The Journal of Clinical Endocrinology & Metabolism · 2016 · 41 citations
    28. Non polycystic ovary syndrome–related endocrine disorders associated with hirsutism European Journal of Clinical Investigation · 2011 · 39 citations
    29. Resistance to the Insulin and Elevated Level of Androgen: A Major Cause of Polycystic Ovary Syndrome Frontiers in Endocrinology · 2021 · 36 citations
    30. Urinary steroids in women with androgenic alopecia Clinical Biochemistry · 2000 · 16 citations