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Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.

Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might reduce it. AST decreases recurrence-free survival but doesn't affect overall survival or progression-free survival. More research is needed to understand AST's benefits.

Androgen suppression therapy (AST) doesn't significantly lower bladder cancer risk, but using finasteride, a type of AST, might decrease the risk. AST also lessens the chance of cancer coming back but doesn't really affect survival rates. More research is needed to understand AST's benefits for different bladder cancers.

Certain genetic variants increase the risk of resistance to hormone therapy in prostate cancer patients.

Androgen use may increase the risk of stroke, but more research is needed.

Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Analog 23 is a promising compound for prostate cancer treatment.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Testosterone replacement therapy helps manage deficiency and has various methods, but requires careful monitoring to avoid side effects.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.

CT scans can find serious prostate cancer even when PSA levels are low.

Testosterone may influence COVID-19 severity and outcomes.

Sex hormones may influence COVID-19 severity, with males at higher risk, and certain hormone therapies could potentially treat the virus.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Swedish men with the E213 A-allele of the androgen receptor have a lower risk of prostate cancer.

A protein called CBP is found in prostate cancer and can increase the effectiveness of certain prostate cancer treatments.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Long-term use of dutasteride for enlarged prostate may worsen blood sugar, cholesterol, and erectile dysfunction.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Androgens may worsen COVID-19 and hair loss could indicate the disease's severity.

5α-reductase inhibitors can cause sexual problems, higher risk of aggressive prostate cancer, and depression.

Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Dutasteride and finasteride affect different cell types differently.

We need better ways to test and understand SARMs to make safer and more effective treatments.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.