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    Glossary Androgen Activity

    effects of male sex hormones on body tissues

    Androgen activity refers to the effects that androgens, which are male sex hormones like testosterone, have on the body. These hormones bind to specific receptors in various tissues, influencing characteristics such as hair growth, muscle mass, and the development of male secondary sexual characteristics. In the context of hair, increased androgen activity can lead to conditions like androgenic alopecia, commonly known as male or female pattern baldness.

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    1. Serum Androgen Bioactivity in Adolescence: A Longitudinal Study of Boys with Constitutional Delay of Puberty The Journal of Clinical Endocrinology & Metabolism · 2004 · 19 citations
    2. Serum androgen bioactivity is low in children with premature adrenarche Pediatric Research · 2014 · 17 citations
    3. Tri-Culture Fermentation of Neem (Azadirachta indica) Leaves Induces Phytochemical Remodeling and Enhances Multi-Target Bioactivities Relevant to Androgenetic Alopecia Plants · 2026
    4. Mixed-Culture Fermentation of Coffee Pulp Induces Metabolomic Changes and Enhances Multi-Target Bioactivity Relevant to Androgenetic Alopecia International Journal of Molecular Sciences · 2026
    5. Hormonal activity in commonly used Black hair care products: evaluating hormone disruption as a plausible contribution to health disparities 2021 · 25 citations
    6. Modelling androgen synthesis and action during human sexual differentiation ePrints Soton (University of Southampton) · 2010
    7. Effect of norplant on androgens and sexual function Fertility and Sterility · 2004
    8. In vitro bioassays for androgens and their diagnostic applications Human Reproduction Update · 2007 · 34 citations
    9. Androgen excess: a hallmark of polycystic ovary syndrome Frontiers in endocrinology · 2023
    10. Androgens modulate keratinocyte differentiation indirectly through enhancing growth factor production from dermal fibroblasts Journal of dermatological science · 2019 · 20 citations
    11. Anti-Androgen Effects of Extracts and Compounds from<i>Ganoderma lucidum</i> Chemistry & Biodiversity · 2009 · 20 citations
    12. QSAR Analysis of a Series of Hydantoin‐based Androgen Receptor Modulators and Corresponding Binding Affinities Molecular Informatics · 2019
    13. Computational Evaluation of Dibenzo Compounds as Potential Dual Inhibitors of Androgen Receptor and 5α-Reductase Asian journal of Current Research in Clinical Cancer · 2022
    14. Blockade of Androgen Markers Using a Novel Betasitosterol, Thioctic Acid and Carnitine-containing Compound in Prostate and Hair Follicle Cell-based Assays Phytotherapy Research · 2016 · 3 citations
    15. Multi-Approach Assessment of Albizia saponaria Bioactivity Against Dandruff-Related Bacteria and Fungi Journal of Hunan University Natural Sciences · 2026
    16. Novel prospectives of shikimic acid and Prunus mume extract for enhancing bioactivity on 5α-reductase and stability in cosmetic patches for acne treatment Frontiers in Natural Products · 2026
    17. Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern Hair Loss and Telogen Effluvium Dermatology Research and Practice · 2020 · 10 citations
    18. In Search of Predictive Models for Inhibitors of 5-alpha Reductase 2 Based on the Integration of Bioactivity and Molecular Descriptors Data. IWBBIO · 2014
    19. Use of genetics in the prediction of success in male pattern hair loss therapy and mechanistic studies Frontiers in Pharmacology · 2026
    20. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    21. Pathways to inflammation: acne pathophysiology European Journal of Dermatology · 2011 · 68 citations
    22. Sex Hormone-Binding Globulin (SHBG) as an Early Biomarker and Therapeutic Target in Polycystic Ovary Syndrome International Journal of Molecular Sciences · 2020 · 58 citations
    23. Synthesis and in Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-oxo-4-androstene-17.beta.-carboxamides as 5.alpha.-Reductase Inhibitors and Antiandrogens Journal of Medicinal Chemistry · 1995 · 12 citations
    24. Establishing and Verifying a Robust Liquid Chromatography-Tandem Mass Spectrometry Method to Simultaneously Measure Seven Androgens Present in Plasma Samples Separations · 2022 · 3 citations
    25. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    26. Acne Harper's Textbook of Pediatric Dermatology · 2011 · 2 citations
    27. Signaling pathways and targeted therapeutic strategies for polycystic ovary syndrome Frontiers in endocrinology · 2023
    28. Alternative androgen pathways WikiJournal of Medicine · 2023
    29. Polycystic Ovary Syndrome in Adolescents Current Women's Health Reviews · 2010
    30. Unrevealing the Potential of Sansevieria trifasciata Prain Fraction for the Treatment of Androgenetic Alopecia by Inhibiting Androgen Receptors Based on LC-MS/MS Analysis, and In-Silico Studies Molecules · 2022