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    Glossary Androgen Activity

    effects of male sex hormones on body tissues

    Androgen activity refers to the effects that androgens, which are male sex hormones like testosterone, have on the body. These hormones bind to specific receptors in various tissues, influencing characteristics such as hair growth, muscle mass, and the development of male secondary sexual characteristics. In the context of hair, increased androgen activity can lead to conditions like androgenic alopecia, commonly known as male or female pattern baldness.

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    1. Prenatal and adult androgen activities in alcohol dependence Acta psychiatrica Scandinavica · 2017 · 63 citations
    2. Intratumoral <i>De Novo</i> Steroid Synthesis Activates Androgen Receptor in Castration-Resistant Prostate Cancer and Is Upregulated by Treatment with CYP17A1 Inhibitors Cancer research · 2011 · 402 citations
    3. Identification of Anabolic Selective Androgen Receptor Modulators with Reduced Activities in Reproductive Tissues and Sebaceous Glands 2009 · 36 citations
    4. Guava (Psidium guajava L.) Leaf Extract as Bioactive Substances for Anti-Androgen and Antioxidant Activities Plants · 2022 · 7 citations
    5. The Expressions of Androgen Receptors and Estrogen Receptors in Bald and Non-bald Area of Androgenic Alopecia Journal of Clinical Dermatology · 2002 · 1 citations
    6. Exercise activates the PI3K-AKT signal pathway by decreasing the expression of 5α-reductase type 1 in PCOS rats Scientific reports · 2018 · 28 citations
    7. Antiandrogenic activities of<i>Glycyrrhiza glabra</i>in male rats International Journal of Andrology · 2009 · 15 citations
    8. Inhibitory activities of some traditional Chinese herbs against testosterone 5α-reductase and effects of Cacumen platycladi on hair re-growth in testosterone-treated mice Journal of Ethnopharmacology · 2015 · 25 citations
    9. Anti-androgenic and Hair Growth Promoting Activities of Lygodii Spora (Spore of Lygodium japonicum) I. Active Constituents Inhibiting Testosterone 5.ALPHA.-Reductase. Biological & Pharmaceutical Bulletin · 2002 · 38 citations
    10. Pharmacokinetic parameters and mechanisms of inhibition of rat type 1 and 2 steroid 5α-reductases: determinants for different in vivo activities of GI198745 and finasteride in the rat 3 3Abbreviations: r5AR1, rat 5α-reductase 1; r5AR2, rat 5α-reductase 2; and DHT, dihydrotestosterone. Biochemical Pharmacology · 2001 · 22 citations
    11. Mechanism of action of bolandiol (19-nortestosterone-3β,17β-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities 2009 · 11 citations
    12. Gender differences in skin: A review of the literature Gender Medicine · 2007 · 152 citations
    13. Mitotic activity in the epidermis of the rabbit stimulated with local applications of testosterone propionate The journal of experimental zoology · 1949 · 25 citations
    14. Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm The World Journal of Men's Health · 2020 · 17 citations
    15. Prevention of Male Late-Onset Hypogonadism by Natural Polyphenolic Antioxidants Nutrients · 2024 · 12 citations
    16. Potential targets in the discovery of new hair growth promoters for androgenic alopecia Expert Opinion on Therapeutic Targets · 2014 · 59 citations
    17. Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin 2001 · 196 citations
    18. Evaluation of the rodent Hershberger assay using three reference endocrine disrupters (androgen and antiandrogens) Reproductive Toxicology · 2003 · 37 citations
    19. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    20. Steroid plant hormones: Effects outside plant kingdom Steroids · 2014 · 46 citations
    21. Anti-androgenic activities of the triterpenoids fraction of Ganoderma lucidum Food Chemistry · 2006 · 64 citations
    22. Synthesis and biological evaluation of amino-pyridines as androgen receptor antagonists for stimulating hair growth and reducing sebum production Bioorganic & Medicinal Chemistry Letters · 2007 · 17 citations
    23. Novel progestogenic androgens for male contraception: design, synthesis, and activity of C7 α-substituted testosterone Biology of reproduction · 2023
    24. Altered brain and pituitary androgen metabolism by prenatal, perinatal or pre- and postnatal finasteride, flutamide or dihydrotestosterone treatment in juvenile male rats Progress in Neuro-psychopharmacology & Biological Psychiatry · 1993 · 26 citations
    25. 4-(Alkylthio)- and 4-(arylthio)-benzonitrile derivatives as androgen receptor antagonists for the topical suppression of sebum production Bioorganic & Medicinal Chemistry Letters · 2009 · 11 citations
    26. Chapter 17. Selective androgen receptor modulators (SARMs) Annual Reports in Medicinal Chemistry · 2001 · 18 citations
    27. Influence of estrogens on the androgen metabolism in different subunits of human hair follicles. PubMed · 2001 · 41 citations
    28. In vitro bioassays for androgens and their diagnostic applications Human Reproduction Update · 2007 · 34 citations
    29. Androgen receptor in rat liver: Characterization and separation from a male-specific estrogen-binding protein Archives of biochemistry and biophysics · 1989 · 24 citations
    30. Androgen receptor modulators: a review of recent patents and reports (2012-2018) Expert Opinion on Therapeutic Patents · 2019 · 23 citations