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    Glossary Anagen Hair Follicles

    phase where hair actively grows

    Anagen hair follicles, also known as growing hair follicles or active hair follicles, are in the phase of the hair growth cycle where the hair is actively growing. This phase can last anywhere from 2 to 7 years, during which the hair shaft is continuously produced by the follicle, resulting in longer hair. This is the most prolonged phase of the hair cycle and is crucial for determining the length of the hair.

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    1. Morus alba Root Extract Induces the Anagen Phase in the Human Hair Follicle Dermal Papilla Cells Pharmaceutics · 2021 · 28 citations
    2. Exposure to gamma-rays at the telogen phase of the hair cycle inhibits hair follicle regeneration at the anagen phase in mice Institutional Repositories DataBase (IRDB) · 2013
    3. Histochemistry of the human hair follicle with consideration of anagen phases I to VI Acta Histochemica · 1992 · 18 citations
    4. Exposure to gamma-rays at the telogen phase of the hair cycle inhibits hair follicle regeneration at the anagen phase in mice International Journal of Radiation Biology · 2013 · 6 citations
    5. Effect of <i>Plantago asiatica L</i>. extract on the anagen phase in human hair follicle dermal papilla cells Journal of Cosmetic Dermatology · 2023 · 5 citations
    6. Exposure to gamma-rays at the telogen phase of the hair cycle inhibits hair follicle regeneration at the anagen phase in mice Institutional Repositories DataBase (IRDB) · 2013
    7. A spermidine-based nutritional supplement prolongs the anagen phase of hair follicles in humans: a randomized, placebo-controlled, double-blind study Dermatology practical & conceptual · 2017 · 8 citations
    8. CARI ONE Induces Anagen Phase of Telogenic Hair Follicles Through Regulation of β-Catenin, Stimulation of Dermal Papilla Cell Proliferation, and Melanogenesis Journal of Dietary Supplements · 2014 · 3 citations
    9. PDGF isoforms induce and maintain anagen phase of murine hair follicles Journal of Dermatological Science · 2006 · 136 citations
    10. 575 An extract of Leontopodium alpinum prolongs anagen phase in human hair follicles ex vivo Journal of Investigative Dermatology · 2021
    11. Oral Spermidine Supplementation Prolongs Hair Follicle Anagen Phase with Sustained Effects: A Randomized, Double-Blind, Placebo-Controlled Trial MEDS Public Health and Preventive Medicine · 2025
    12. The mouse hairy ears mutation exhibits an extended growth (anagen) phase in hair follicles and altered <i>Hoxc</i> gene expression in the ears Veterinary Dermatology · 2008 · 10 citations
    13. Adenosine stimulates growth of dermal papilla and lengthens the anagen phase by increasing the cysteine level via fibroblast growth factors 2 and 7 in an organ culture of mouse vibrissae hair follicles International Journal of Molecular Medicine · 2011 · 28 citations
    14. Pea Sprout Extract Promotes Hair Follicle Regeneration via Anagen Phase Prolongation and Dual Modulation of Oxidative and Inflammatory Signaling Journal of Microbiology and Biotechnology · 2025
    15. Novel ALK5 inhibitor TP0427736 reduces TGF-β induced growth inhibition in human outer root sheath cells and elongates anagen phase in mouse hair follicles Pharmacological Reports · 2017 · 14 citations
    16. Expression of the Orphan Protein Plet-1 during Trichilemmal Differentiation of Anagen Hair Follicles 2010 · 30 citations
    17. Single-Cell Transcriptomic Identification of a Proliferative Intermediate State During Early Anagen Hair Follicle Regeneration Genes · 2026
    18. The co-expression pattern of VEGFR-2 with indicators related to proliferation, apoptosis, and differentiation of anagen hair follicles Open Life Sciences · 2023
    19. Mammalian target of rapamycin complex 1 (mTORC1) may modulate the timing of anagen entry in mouse hair follicles Experimental dermatology · 2012 · 28 citations
    20. In vitro methodology, hormonal and nutritional effects and fibre production in isolated ovine and caprine anagen hair follicles Animal · 2010 · 7 citations
    21. Hair Follicle Chemosensation: TRPM5 Signaling Is Required for Anagen Maintenance Journal of Investigative Dermatology · 2021 · 12 citations
    22. 219 STAT5 activation in the dermal papilla is important for hair follicle growth phase induction, hair follicle regeneration and wound healing Journal of Investigative Dermatology · 2016 · 1 citations
    23. Immunohistochemical analysis of tissue remodelling during the anagen—catagen transition of the human hair follicle British Journal of Dermatology · 1997 · 23 citations
    24. 586 Interest of Silybum marianum extract, Manganese PCA and Lespedeza capitata extract in a new anti-hair loss serum to stimulate hair growth and prolong anagen phase Journal of Investigative Dermatology · 2022
    25. STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction Journal of Investigative Dermatology · 2016 · 32 citations
    26. Inhibition of Bmp signaling affects growth and differentiation in the anagen hair follicle The EMBO Journal · 2000 · 305 citations
    27. Extracellular vesicles derived from MSCs activates dermal papilla cell in vitro and promotes hair follicle conversion from telogen to anagen in mice Scientific Reports · 2017 · 113 citations
    28. Leptin of dermal adipose tissue is differentially expressed during the hair cycle and contributes to adipocyte‐mediated growth inhibition of anagen‐phase vibrissa hair Experimental Dermatology · 2014 · 30 citations
    29. Immunization by Application of DNA Vaccine onto a Skin Area Wherein the Hair Follicles Have Been Induced into Anagen-onset Stage Molecular therapy · 2007 · 20 citations
    30. Exploring differentially expressed genes between anagen and telogen secondary hair follicle stem cells from the Cashmere goat (Capra hircus) by RNA-Seq PLoS ONE · 2020 · 27 citations