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Adding chemotherapy to tamoxifen improves survival for older breast cancer patients with positive nodes.

Anti-IL-12/IL-23 antibody therapy effectively treats psoriasiform skin lesions in IBD patients.

Polycystic ovaries are defined by having 12 or more small follicles in each ovary and are found in up to 33% of women, while Polycystic Ovary Syndrome (PCOS) is the most common hormone disorder in women of reproductive age, potentially increasing risk of obesity, diabetes, and heart diseases.

Mitochondrial reactive oxygen species are essential for skin and hair development.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The document concludes that mouse models are helpful but have limitations for skin wound healing research, and suggests using larger animals and genetically modified mice for better human application.

Women with PCOS often have more belly fat and higher insulin levels, but belly fat isn't the only cause of their insulin resistance.

5% minoxidil works better for hair growth and density, with minor irritation.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The study found that sweat glands contain different types of stem cells that help with healing and maintaining healthy skin.

Zinc oxide nanoparticles in sunscreen do not penetrate deep into the skin.

ADSCs help in wound healing and skin regeneration but need more research for full understanding.

There is no standardized treatment for hidradenitis suppurativa, and individualized plans are needed.

Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

Apoptosis is essential for human skin development and forming a functional epidermis.

The immune system plays a key role in tissue repair, affecting both healing quality and regenerative ability.

Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Human skin can make serotonin and melatonin.

Wnt1/βcatenin signaling is crucial for heart repair after injury.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Dermatoscopy is useful for identifying different hair and scalp conditions and can reduce the need for biopsies.

The document concludes that the fast-growing direct-to-consumer genetic testing market lacks sufficient regulation, posing risks to consumers due to questionable test quality and accuracy.

Dandruff and seborrheic dermatitis are caused by yeast feeding on scalp oils, leading to irritation and flaking.

Men over 50 may experience hormone decline causing various symptoms, and proper management is crucial.

Finasteride doesn't effectively treat hair loss in postmenopausal women.

Hidradenitis suppurativa, a chronic skin disease, can be managed with antibiotics, lifestyle changes, and in severe cases, surgery. Early diagnosis and careful planning are key, and laser treatment can be an efficient solution for mild to severe cases.

Hair growth and pigmentation in mice involve specific stages crucial for research.

Men with baldness due to androgenetic alopecia still have hair stem cells, but lack specific cells needed for hair growth.