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    Glossary AMP-activated protein kinase

    regulates cellular energy by activating ATP-producing pathways

    AMP-activated protein kinase (AMPK) is an enzyme that plays a crucial role in cellular energy regulation. It acts as a cellular energy sensor, activating pathways that generate ATP (the cell's energy currency) when energy levels are low and inhibiting processes that consume ATP when energy is abundant. This helps maintain energy balance within cells and is important for overall metabolic health.

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    1. Salicylate induces epithelial actin reorganization via activation of the AMP-activated protein kinase and promotes wound healing and contraction in mice Scientific Reports · 2024 · 8 citations
    2. Forsythiaside A Activates AMP-Activated Protein Kinase and Regulates Oxidative Stress via Nrf2 Signaling International Journal of Molecular Sciences · 2023 · 7 citations
    3. AMP-activated Protein Kinase 활성체인 Metformin의 모발 성장에 미치는 영향 대한피부과학회지 · 2019
    4. Metformin, an Activator of AMPK, Promotes the Growth of Hair Follicles via the AMPK/β-catenin Signaling Pathway Journal of Clinical Dermatology · 2019
    5. AMPK Phosphorylates ZDHHC13 to Increase MC1R Activity and Suppress Melanomagenesis Cancer Research · 2023 · 24 citations
    6. Sesn2/AMPK/mTOR signaling mediates balance between survival and apoptosis in sensory hair cells under stress Cell death and disease · 2017 · 21 citations
    7. Integrated miRNA-mRNA analysis reveals regulatory pathways underlying the curly fleece trait in Chinese tan sheep BMC genomics · 2018 · 17 citations
    8. Adenine supplement delays senescence in cultured human follicle dermal papilla cells Experimental dermatology · 2015 · 6 citations
    9. Glycolytic Dysfunction in Granulosa Cells and Its Contribution to Metabolic Dysfunction in Polycystic Ovary Syndrome Drug Design Development and Therapy · 2025 · 3 citations
    10. Adipose tissue protects against skin photodamage through CD151- and AdipoQ- EVs Cell Communication and Signaling · 2024
    11. Modulating Aging and Aging-related Symptoms Using Endogenous Small Molecules 2019
    12. Hypothalamic lipid metabolism and the control of food intake Tesis Doctorals en Xarxa (Consorci de Serveis Universitaris de Catalunya) · 2016
    13. Vitamin B12 Activates the Wnt-Pathway in Human Hair Follicle Cells by Induction of <i>beta</i>-Catenin and Inhibition of Glycogensynthase Kinase-3 Transcription Journal of Cosmetics, Dermatological Sciences and Applications · 2011 · 4 citations
    14. Therapeutic Potential of Topical Metformin in Diabetic Wound Healing: Preclinical Mechanistic Insights Jurnal Kesehatan · 2026
    15. The Molecular Mechanism Underlying the Proliferating and Preconditioning Effect of Vitamin C on Adipose-Derived Stem Cells Stem Cells and Development · 2014 · 42 citations
    16. LL-37 stimulates the functions of adipose-derived stromal/stem cells via early growth response 1 and the MAPK pathway Stem cell research & therapy · 2016 · 53 citations
    17. Topical metformin as a novel therapy for alopecia areata due to its immunologic effects Medical Hypotheses · 2023
    18. A Review of Metabolic Dysregulation in Lymphocytic Cicatricial Alopecia: Exploring the Connections and Therapeutic Implications Journal of Investigative Dermatology · 2025 · 1 citations
    19. Factors regulating quiescent stem cells: insights from the intestine and other self-renewing tissues The Journal of Physiology · 2015 · 8 citations
    20. Genetic alteration of cyclic adenosine 3',5'-monophosphate-dependent protein kinase subunit expression affects calcium currents and beta-endorphin release in AtT-20 clonal pituitary cells. Molecular Endocrinology · 1994
    21. TOR tour to auxin EMBO journal · 2013 · 32 citations
    22. Myristoleic Acid Promotes Anagen Signaling by Autophagy through Activating Wnt/β-Catenin and ERK Pathways in Dermal Papilla Cells Biomolecules & therapeutics · 2021 · 8 citations
    23. 1325 Age-dependent loss of the stemness and antimicrobial defense function of dermal fibroblasts is mediated by TGFbeta Journal of Investigative Dermatology · 2018
    24. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    25. PAK4 signaling in health and disease: defining the PAK4–CREB axis Experimental & Molecular Medicine · 2019 · 81 citations
    26. Functionally enhanced placenta-derived mesenchymal stem cells inhibit adipogenesis in orbital fibroblasts with Graves’ ophthalmopathy 2020
    27. Epidermal Polarity Genes in Health and Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 32 citations
    28. Activator Protein-1 Activity Regulates Epithelial Tumor Cell Identity Cancer Research · 2006 · 70 citations
    29. Protein Kinase Cε, which Sensitizes Skin to Sun's UV Radiation–Induced Cutaneous Damage and Development of Squamous Cell Carcinomas, Associates with Stat3 Cancer Research · 2007 · 76 citations
    30. A preliminary study of differentially expressed genes in expanded skin and normal skin: implications for adult skin regeneration Archives of Dermatological Research · 2011 · 16 citations