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    Research 211–240 of 370

    1. Sebum Free Fatty Acids Enhance the Innate Immune Defense of Human Sebocytes by Upregulating β-Defensin-2 Expression Journal of Investigative Dermatology · 2009 · 195 citations
    2. Agouti and Agouti-related Protein: Analogies and Contrasts Journal of Biological Chemistry · 2000 · 135 citations
    3. Intracrine androgen biosynthesis, metabolism and action revisited Molecular and Cellular Endocrinology · 2017 · 131 citations
    4. Genetically Altered Expression of Spermidine/Spermine N1-Acetyltransferase Affects Fat Metabolism in Mice via Acetyl-CoA Journal of Biological Chemistry · 2006 · 128 citations
    5. A Receptor-Like Kinase Mediates Ammonium Homeostasis and Is Important for the Polar Growth of Root Hairs in<i>Arabidopsis</i> ˜The œPlant cell · 2014 · 107 citations
    6. Targeting of Smoothened for therapeutic gain Trends in Pharmacological Sciences · 2014 · 105 citations
    7. The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches Pharmacology & Therapeutics · 2004 · 83 citations
    8. Free Testosterone: Pumping up the Tires or Ending the Free Ride? Endocrine Reviews · 2017 · 78 citations
    9. Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review Expert opinion on therapeutic patents · 2017 · 70 citations
    10. Amino acid–derived defense metabolites from plants: A potential source to facilitate novel antimicrobial development Journal of Biological Chemistry · 2021 · 69 citations
    11. Preclinical Pharmacology, Antitumor Activity, and Development of Pharmacodynamic Markers for the Novel, Potent AKT Inhibitor CCT128930 Molecular cancer therapeutics · 2011 · 65 citations
    12. SARS-CoV-2 Non-Structural Proteins and Their Roles in Host Immune Evasion Viruses · 2022 · 52 citations
    13. Therapeutics for COVID-19 and post COVID-19 complications: An update Current Research in Pharmacology and Drug Discovery · 2022 · 52 citations
    14. Ornithine Decarboxylase Expression Leads to Translocation and Activation of Protein Kinase CK2 in Vivo Journal of Biological Chemistry · 1997 · 52 citations
    15. An essential role for <i>Rxrα</i> in the development of Th2 responses European Journal of Immunology · 2005 · 50 citations
    16. 5α-reduced progestogens ameliorate mood-related behavioral pathology, neurotoxicity, and microgliosis associated with exposure to HIV-1 Tat Brain Behavior and Immunity · 2016 · 47 citations
    17. Overview of Caffeine Effects on Human Health and Emerging Delivery Strategies Pharmaceuticals · 2023 · 43 citations
    18. Down-regulation of Melanocortin Receptor Signaling Mediated by the Amino Terminus of Agouti Protein in XenopusMelanophores Journal of Biological Chemistry · 1999 · 43 citations
    19. Host-Directed FDA-Approved Drugs with Antiviral Activity against SARS-CoV-2 Identified by Hierarchical In Silico/In Vitro Screening Methods Pharmaceuticals · 2021 · 42 citations
    20. Persistent escalation of alcohol consumption by mice exposed to brief episodes of social defeat stress: suppression by CRF-R1 antagonism 2018 · 38 citations
    21. Identification of sirtuin 1 as a promising therapeutic target for hypertrophic scars British journal of pharmacology · 2016 · 36 citations
    22. Pain in Multiple Sclerosis: Understanding Pathophysiology, Diagnosis, and Management Through Clinical Vignettes Frontiers in Neurology · 2022 · 35 citations
    23. Ethanol intake patterns in female mice: Influence of allopregnanolone and the inhibition of its synthesis Drug and Alcohol Dependence · 2008 · 35 citations
    24. Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth EMBO journal · 2018 · 34 citations
    25. Allopregnanolone in the bed nucleus of the stria terminalis modulates contextual fear in rats Frontiers in Behavioral Neuroscience · 2015 · 34 citations
    26. Divergent neuroactive steroid responses to stress and ethanol in rat and mouse strains: relevance for human studies Psychopharmacology · 2014 · 34 citations
    27. Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat Frontiers in Cellular Neuroscience · 2015 · 32 citations
    28. Rare and common genetic determinants of metabolic individuality and their effects on human health Nature Medicine · 2022 · 29 citations
    29. Structural mechanism of TRPV3 channel inhibition by the plant‐derived coumarin osthole EMBO reports · 2021 · 28 citations
    30. CXXC5: A novel regulator and coordinator of TGF-β, BMP and Wnt signaling Journal of Cellular and Molecular Medicine · 2018 · 28 citations