Search

everythinglearnresearchcommunity

for

Search:↓

Alpha-difluoromethylornithine prevents cancer in mice but causes hair loss.

MK-2206 was safe and effectively blocked AKT signaling in cancer patients, warranting more trials.

Early changes in brain chemicals affect how a drug reduces alcohol intake in rats.

CBD-rich hemp oil can significantly increase hair regrowth in people with common hair loss, with no reported side effects.

The androgen receptor's shape-changing ability helps it function but can lead to cancer treatment resistance.

The TRPV3 channel structure changes linked to severe itch and hyperkeratosis were identified using cryo-EM.

Brain-made chemicals can control nerve cell function differently in various parts of a mouse's brain, which may help us understand neurological conditions.

Increasing TSPO in the brain reduces anxiety and depression.

Blocking allopregnanolone production in mice makes them more anxious after stress, but this can be reversed with a drug that mimics allopregnanolone.

NIPP1 is important for healthy skin and could help treat skin inflammation.

Changing neuroactive steroid levels early in life can affect how adult rats respond to alcohol's stimulating effects.

New CRISPR/Cas9 variants and nanotechnology-based delivery methods are improving cancer treatment, but choosing the best variant and overcoming certain limitations remain challenges.

Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.

Afatinib, neratinib, and zanubrutinib could be effective against KRASG12C-mutant tumors.

Hair color is determined by melanin produced and transferred in hair follicles.

Free fatty acids in sebum boost skin's defense against acne by increasing antimicrobial peptides.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Altering SSAT affects fat metabolism and body fat in mice.

The CAP1 gene helps control ammonium levels and is necessary for the proper growth of root hairs in Arabidopsis.

Targeting the Smoothened receptor shows promise for treating certain cancers.

The review suggests that while many AKR1C3 inhibitors show promise for treating certain cancers, more research is needed to confirm their effectiveness in humans.

CCT128930 is a promising new drug that effectively targets and inhibits a cancer-related protein, showing potential for cancer treatment.

New treatments for COVID-19 show promise, but more effective antiviral drugs are needed.

High ornithine decarboxylase levels may lead to hair loss and cancer by increasing CK2 activity in the nucleus.

RXRα is crucial for proper immune response and links diet to immune function.

Agouti protein affects melanocortin receptors through competitive antagonism and receptor down-regulation.

Sirtuin 1 could be a potential drug target for treating hypertrophic scars.

Genetic variations greatly affect individual metabolism and can impact health and disease risk.

Osthole inhibits the TRPV3 channel by binding to specific sites, potentially aiding drug development for skin diseases and cancers.

CXXC5 is a protein that controls cell growth and healing processes, and changes in its activity can lead to diseases like cancer and hair loss.