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    Glossary Alkaline Phosphatase Activity

    enzyme function indicating liver or bone health

    Alkaline Phosphatase Activity (ALP Activity) refers to the function of the enzyme alkaline phosphatase, which is found in various tissues throughout the body, including the liver, bones, kidneys, and digestive system. This enzyme plays a crucial role in breaking down proteins and is often measured in blood tests to assess liver function, bone health, and to diagnose certain medical conditions. Elevated or decreased levels of ALP can indicate issues such as liver disease, bone disorders, or other health problems.

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    1. Valproic Acid Induces Hair Regeneration in Murine Model and Activates Alkaline Phosphatase Activity in Human Dermal Papilla Cells PLOS ONE · 2012 · 85 citations
    2. Proteomics demonstration that histone H4 is a colchicine-induced retro-modulator of growth and alkaline phosphatase activity in hair follicle dermal papilla culture Journal of proteomics · 2011 · 5 citations
    3. Dermal Papilla Cells Serially Cultured with Wnt-10b Sustain their Hair Follicle Induction Activity after Transplantation into Nude Mice Cell Transplantation · 2012 · 22 citations
    4. Hair Growth–Promoting Activity of Flavone-Rich Fractions Derived from Eremochloa ophiuroides extracts The Korean Society for Veterinary Nursing · 2026
    5. Hair Growth-Promoting Activity of Citron Seed Oil: Induction of Premature Telogen-To-Anagen Transition of Hair Follicle in C57BL/6 Mouse Models Current Topics in Nutraceutical Research · 2021
    6. BIOCHEMICAL ANALYSIS OF HAIR GROWTH FROM THE ASPECTS OF AGING AND ENZYME ACTIVITIES The Journal of Dermatology · 1983 · 46 citations
    7. Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture Molecules · 2022 · 7 citations
    8. Hepatoprotective Activity of Yellow Chinese Chive against Acetaminophen-Induced Acute Liver Injury via Nrf2 Signaling Pathway Journal of Nutritional Science and Vitaminology · 2020 · 2 citations
    9. Alkaline Phosphatase in Alopecia Areata Archives of Dermatology · 1957 · 23 citations
    10. Alkaline Phosphatase Reaction in Hair Follicles of Male Beagle Dogs during Hair Cycle Stages* Anatomia Histologia Embryologia · 1978 · 2 citations
    11. Supplementary Material for: Metformin Promotes the Hair-Inductive Activity of Three-Dimensional Aggregates of Epidermal and Dermal Cells Self-Assembled In Vitro Figshare · 2021
    12. The effect of adipose-derived stem cell exosomes on the biological activity of dermal papilla cells DOAJ (DOAJ: Directory of Open Access Journals) · 2022
    13. Baicalin, a flavonoid, affects the activity of human dermal papilla cells and promotes anagen induction in mice Naunyn-Schmiedeberg's Archives of Pharmacology · 2014 · 22 citations
    14. Cultured Peribulbar Dermal Sheath Cells Can Induce Hair Follicle Development and Contribute to the Dermal Sheath and Dermal Papilla Journal of Investigative Dermatology · 2003 · 208 citations
    15. Histochemical and Immunohistochemical Markers for Human Eccrine and Apocrine Sweat Glands: An Aid for Histopathologic Differentiation of Sweat Gland Tumors Journal of Investigative Dermatology Symposium Proceedings · 2001 · 73 citations
    16. Preparation of hair beads and hair follicle germs for regenerative medicine Biomaterials · 2019 · 51 citations
    17. Dissociated Human Dermal Papilla Cells Induce Hair Follicle Neogenesis in Grafted Dermal–Epidermal Composites Journal of Investigative Dermatology · 2013 · 51 citations
    18. Sequential Morphologic and Clinicopathologic Alterations in Dogs with Experimentally Induced Glucocorticoid Hepatopathy American Journal of Veterinary Research · 1981 · 48 citations
    19. Hair growth-promoting effect of Aconiti Ciliare Tuber extract mediated by the activation of Wnt/β-catenin signaling Life Sciences · 2012 · 45 citations
    20. Rescuing key native traits in cultured dermal papilla cells for human hair regeneration Journal of Advanced Research · 2020 · 30 citations
    21. Peppermint Oil Promotes Hair Growth without Toxic Signs Toxicological Research · 2014 · 30 citations
    22. Dermal papilla cells induce keratinocyte tubulogenesis in culture Histochemistry and cell biology · 2010 · 28 citations
    23. TSA restores hair follicle-inductive capacity of skin-derived precursors Scientific Reports · 2019 · 18 citations
    24. NFIC promotes the vitality and osteogenic differentiation of rat dental follicle cells Journal of Molecular Histology · 2019 · 11 citations
    25. Defining ovine dermal papilla cell markers and identifying key signaling pathways regulating its intrinsic properties Frontiers in Veterinary Science · 2023 · 5 citations
    26. Osteogenic Potential of Mesenchymal Stem Cells from Adipose Tissue, Bone Marrow and Hair Follicle Outer Root Sheath in a 3D Crosslinked Gelatin-Based Hydrogel International journal of molecular sciences · 2021 · 2 citations
    27. Upcycled Postbiotic Cell-Free Supernatants from Limosilactobacillus fermentum MG901 and MG4237 Alleviated Oxidative Stress-Induced Dysfunction in Human Follicle Dermal Papilla Cells Cosmetics · 2026
    28. BH06 (P075) A randomized controlled trial comparing the efficacy and safety of oral tofacitinib vs. methotrexate in moderate-to-severe alopecia areata British Journal of Dermatology · 2025
    29. P075 A randomized controlled trial comparing the efficacy and safety of oral tofacitinib vs. methotrexate in moderate-to-severe alopecia areata British Journal of Dermatology · 2025
    30. The potential of Spirulina maxima extract-treated conditioned medium from adipose-derived mesenchymal stem cells for hair growth promoting effect on human dermal papilla cells Regenerative Therapy · 2025