June 2023 in “Journal of Pharmaceutical and Health Research” In this study with guinea pigs, a hair tonic containing 0.001% caffeine significantly stimulated hair growth, showing higher effectiveness with an average hair length of 18.294 mm compared to a tonic with 0.005% caffeine concentration, which resulted in an average hair length of 16.610 mm.
March 2023 in “Jurnal Ilmiah Medicamento” In this study, herbal hair tonic made from Usada Bali ingredients significantly increased hair growth in mice without causing skin irritation compared to a negative control.
January 2022 in “Buletin penelitian tanaman rempah dan obat/Bulletin komunikasi penelitian tanaman rempah dan obat” This study observed that a hair tonic containing 3% ethanolic extract of bidara leaves stimulated rabbit hair growth more effectively over 28 days than both distilled water and 2% minoxidil, attributing this effect to the extract's anti-inflammatory and antioxidant properties.
February 2020 in “Diabetologie Und Stoffwechsel” This article reviews treatment strategies for polycystic ovary syndrome, specifically recommending letrozole for infertility, while also discussing lifestyle changes and other potential therapies, and reports no new research findings.
1 citations
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July 2022 in “Bandung Conference Series. Pharmacy” This study found that a hair tonic formulation using candlenut oil as an active ingredient could significantly promote hair growth in rabbits, achieving 29.77 mm in 22 days.
1 citations
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January 2015 This abstract discusses the use of walnut seed oil for hair care but does not provide new research findings or experimental results.
October 2025 in “Phytochemistry Letters” April 2019 in “Journal of Investigative Dermatology” This study demonstrates that DHT-induced lipid synthesis in sebocytes involves the mTOR pathway, suggesting mTOR inhibitors may help modulate androgen-dependent sebum overproduction.
This study reported that analyzing hair cortisol levels using a validated online SPE LC-MS method provided a way to assess long-term hormone secretion in 114 healthy volunteers, with a median hair cortisol value of 4.76 pg/mg.
53 citations
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November 2014 in “International Journal of Oncology” This study found that wedelolactone, a natural compound from plants, inhibited breast cancer-mediated osteoclast differentiation and activity in vitro, suggesting its potential as a therapy for bone destruction in breast cancer bone metastasis.
12 citations
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November 2024 in “International Journal of Molecular Sciences” This study found that hydroxytyrosol significantly alleviated acute liver injury in mice by suppressing inflammation and targeting the TNF-α/PI3K/AKT signaling pathway.
4 citations
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May 2024 in “Cytotechnology” 2 citations
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April 2022 in “Der Hautarzt” This review discusses the current literature on platelet rich plasma injections for androgenetic alopecia, noting that while some studies report positive outcomes, they often suffer from methodological weaknesses and inconsistent results.
1 citations
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May 2025 in “Natural Products and Bioprospecting” In this study, PEVIII, a nanocomposite chitosan-coated vesicle containing both α-hederin and hederacoside C, demonstrated notable antibacterial activity against Pseudomonas aeruginosa in a keratitis model, showing significant lesion reduction, tissue improvement, and decreased bacterial load and inflammatory markers compared to other treatments.
1 citations
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January 2014 in “Jurnal Tata Rias” In this study, the hair tonic with a 3:3 avocado extract to honey ratio was most preferred by panelists and may be suitable for preventing hair loss.
April 2026 in “International Journal of Biological Macromolecules” December 2024 in “Naunyn-Schmiedeberg s Archives of Pharmacology” January 2026 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This study developed a deep-learning model that accurately diagnosed alopecia areata with an accuracy of 88.92% and distinguished its activity levels with an accuracy of 83.33%, highlighting the potential for artificial intelligence in improving the diagnosis and treatment of this autoimmune hair loss condition.
June 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” This study observed that using moringa leaf extract in hair tonic reduced hair loss among the sampled students, with the average hair loss decreasing from 118.75 strands to 79.25 strands per day.
January 2024 in “Wiadomości Lekarskie” This study found that engaging in outdoor physical activities significantly reduced the odds of increased HbA1C levels, lower HDL-cholesterol, and obesity among patients with metabolic syndrome, suggesting potential health benefits for this population.
This narrative review examined the potential of hibiscus leaves and apple skin as natural ingredients for hair tonics and reported their effectiveness in addressing hair loss, highlighting properties like strong antioxidant content and ability to strengthen hair roots.
32 citations
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April 2020 in “PLoS Biology” This study found that Rab5c is crucial for proper HSPC development in zebrafish embryos by regulating Notch and AKT signaling through endocytic trafficking, with both deficiency and overactivation leading to production defects.
9 citations
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September 2024 in “Scientific Reports” This study found that cardamonin may inhibit OSCC cell migration, proliferation, and invasion by affecting the PI3K/AKT pathway, suggesting its potential as a treatment.
7 citations
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March 2025 in “Cytotechnology” 1 citations
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October 2025 in “International Journal of Molecular Sciences” This narrative review highlights the potential of naturally occurring compounds to target specific molecular pathways and overcome resistance in advanced and recurrent papillary thyroid cancer, offering new therapeutic possibilities beyond traditional treatments like surgery and lifelong hormone replacement.
February 2024 in “Jurnal Kesehatan Yamasi Makassar” This study in South Sulawesi Province developed a shampoo using ethanol extract from Pondoh salak fruit peel, which met physical stability tests and demonstrated strong inhibitory effects against Staphylococcus epidermidis and Candida albicans, with formulations ranging from 10% to 20% concentrations.
In this study, researchers found that aloe vera hair tonic preparations containing 10% and 15% extract concentrations significantly enhanced hair growth in rats and remained physically stable across various temperature conditions.
14 citations
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October 2020 in “Journal of ethnopharmacology” This study found that both ethanol and aqueous extracts of Lepidium sativum seeds improved insulin signaling and reduced obesity-related metabolic changes in high-fat diet-fed rats, suggesting potential as a dietary supplement.
5 citations
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October 2023 in “Phytotherapy Research” This study found that dauricine, a natural compound, may inhibit cell growth and enhance apoptosis in neuroblastoma and glioblastoma by blocking the Oct4/Shh pathway and AKT/β-catenin signaling.
1 citations
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April 2023 in “Jurnal Sains Farmasi & Klinis” This study identified various secondary metabolites such as terpenes, phenolic acids, and flavonoids in plants mentioned by Ibnu Sina for hair cosmetic applications.