January 2024 in “Theranostics” This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.
January 2022 in “SSRN Electronic Journal” This study found that lncRNA RP11-818024.3 transfection promoted hair growth in AGA mice and increased cellular proliferation in vitro, potentially involving the FGF2 and PI3K-Akt pathways.
April 2019 in “Journal of Investigative Dermatology” This study found that mice lacking REDD1 experienced an expansion of dermal white adipose tissue through both hypertrophy and hyperplasia, suggesting a potential therapeutic target for skin adipogenesis regulation.
March 2026 in “Jurnal Ilmiah Ibnu Sina (JIIS) Ilmu Farmasi dan Kesehatan” In this in vitro study, the researchers found that garden balsam leaf extract serum showed no antifungal inhibition against Candida albicans, while the positive control, a 2% ketoconazole shampoo, demonstrated a strong effect.
In this study, applying a 5% concentration of pomegranate peel extract significantly enhanced hair growth on male rabbits, showing results comparable to the positive control using 2% Minoxidil, but higher concentrations or lower concentrations did not perform as well.
January 2026 in “Biospecies” In this study, a hair tonic containing black fungus extract was shown to have antifungal activity against Malassezia furfur, with the 70% extract concentration providing the strongest effect.
August 2023 in “Jurnal Pharmacia Mandala Waluya” This study examined the effects of purified Albizia saponaria bark extract on hair growth in rabbits, finding that a 20% concentration of the extract increased hair weight significantly, though it was less effective than minoxidil.
January 2022 in “Lumbung Farmasi: Jurnal Ilmu Kefarmasian/Lumbung Farmasi” In this experimental study, researchers found that a hair tonic combining celery leaf extract and honey, specifically Formula B, showed the highest potential for promoting hair growth in rabbits, with outcomes comparable to a minoxidil control.
October 2021 in “Borneo Journal of Pharmascientech” This study found that combining kemiri oil and garlic oil at a 1:1 ratio with 200 ppm concentration was most effective for promoting rabbit fur growth in terms of length and weight.
This study found that ethanol extract of fragrant pandanus leaves inhibited the growth of the dandruff-causing fungus Pityrosporum ovale, with higher concentrations showing greater inhibitory effects.
This study concluded that bitter melon leaf ethanol extract can be effectively formulated into a shampoo that meets quality standards and promotes rabbit hair growth.
August 2019 in “Pharmacoscript” This study found that a combination of pandanus and sansevieria leaf extracts at a 3:2 ratio showed improved hair growth activity compared to individual extracts and controls.
August 2019 in “Pharmacoscript” This study found that a 3:2 combination of pandanus and sansevieria leaf extracts showed the best hair growth activity compared to using each extract alone.
This study found that ethanol and methanol extracts of Spirulina platensis did not exhibit cytotoxic activity on WiDr colon cancer cells.
This study found that creambath preparations with waru leaf extract accelerated hair growth in New Zealand White rabbits, though none matched the positive control; the 37.5% concentration increased hair weight effectively.
This study found that ethanolic extract and fractions of Ceiba leaf tonic may enhance rabbit hair growth similarly to 2% minoxidil.
September 2016 in “Medical Sains/Medical sains” In this study, applying water extracts of liquorice at a concentration of 2.5% to male rabbits led to the best rate of hair growth at 2.19 cm over 35 days, while a 5% concentration resulted in the greatest hair weight at 0.12 grams.
April 2016 in “Pharmaciana” This study found that a combination of liquorice and aloe vera extracts, particularly combination 1, resulted in the most optimal hair growth in rabbits over a 28-day period.
This study investigated whether combinations of green tea leaf and gotukola extracts could act as a hair growth stimulant but reports no definitive results on the most effective combination.
This study found that a 10% hibiscus leaf extract hair tonic demonstrated better hair growth activity than 2% minoxidil in rabbits but caused eye irritation.
9 citations
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May 2015 in “Media Penelitian dan Pengembangan Kesehatan” This study found that a gel containing apigenin and celery juice improved hair growth in male Spraque-Dawley mice without causing significant skin irritation.
2 citations
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September 2025 in “Frontiers in Pharmacology” In a study using diabetic rats, researchers found that oral empagliflozin accelerated wound healing by reducing inflammation and oxidative stress, indicating potential benefits beyond blood sugar control for managing diabetic wounds.
2 citations
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October 2020 in “Indonesian Journal of Nursing and Health Sciences” This article reviewed literature and found that Alginate-Chitosan-Fucoidan sponges may offer effective alternatives for wound dressing due to their enhanced wound healing abilities, attributed to good hemostatic and antibacterial properties, as well as excellent elasticity.
2 citations
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January 2022 in “JDDG Journal der Deutschen Dermatologischen Gesellschaft” This review discusses current and emerging therapies for alopecia areata, highlighting unmet therapeutic needs and the psychosocial burden on patients but reports no new clinical results.
1 citations
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September 2024 in “Jurnal Ilmiah JKA (Jurnal Kesehatan Aeromedika)” This study found that red galangal rhizome simplicia extract demonstrated the strongest antibacterial effect against Propionibacterium acnes among tested extracts, achieving a 31.5 mm inhibitory zone at a 20% concentration.
1 citations
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December 2018 in “Talenta Conference Series Tropical Medicine (TM)” This study evaluated the antifungal activity of lemongrass oil in anti-dandruff gel shampoo formulations and found that a 10% lemongrass oil concentration was the most effective at inhibiting the growth of the dandruff-causing fungus Pityrosporum ovale.
1 citations
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January 2015 In this study, gel containing apigenin and celery herb extract was observed to effectively stimulate hair growth and did not cause skin irritation in male Sprague-Dawley rats.
August 2025 in “Current Issues in Molecular Biology” This study demonstrated that Periplaneta americana extract significantly promoted hair regeneration in depilated mice by enhancing superoxide dismutase activity, upregulating vascular endothelial growth factor, modulating the FOXO/PI3K/AKT pathway, and restoring skin microbiome balance, suggesting its potential as a novel therapeutic candidate for alopecia.
December 2025 in “Sains Medisina” This review identified 12 herbal plants producing essential oils with pharmacological activities that stimulate hair growth, potentially through enhanced scalp microcirculation, inhibition of 5α-reductase, anti-inflammatory and antioxidant effects, anagen phase stimulation, and increased dermal papilla cell proliferation.
January 2025 in “FASKES Jurnal Farmasi Kesehatan dan Sains” In this study, the researchers used molecular docking to identify Erythrabyssin II from Erythrina subumbrans as a potential candidate for anti-alopecia treatment, comparable to minoxidil, suggesting clinical trials are needed to evaluate its pharmacological effects.