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This review discusses the role of collagen XVII in maintaining stem cell niches and its impact on skin aging and wound repair, without reporting new clinical results.

This study observed that estrogen receptor β and androgen receptor expressions in the skin decline with age, more noticeably under sun exposure, suggesting a role in skin aging.

This study reports that mast cells are not only passive participants but also key regulators in skin aging, and their role as both protectors and accelerators of aging suggests they could be promising therapeutic targets for skin aging interventions.

This narrative review explores how psychological stress may contribute to premature skin aging by affecting dermal collagen and elastin remodeling through neuroendocrine, molecular, and cellular pathways, highlighting potential therapeutic targets to preserve skin structure and function.

This study found that topical mesenchymal stem cell conditioned medium improved skin structure by increasing collagen fiber density, hair follicles, and blood vessel number in a mouse model of skin aging.

In this review, the authors explored how various hormones, particularly IGF-1, GH, estrogens, retinoids, and melatonin, influence human skin aging, highlighting potential new avenues for anti-aging therapies beyond the currently utilized topical retinoids and estrogens.

Loss of COL17A1 causes hair follicle stem cells to age and leads to hair loss.

This study found that as Japanese women age, their hair cuticle becomes more prone to damage, shifting from type L to type E damage patterns, and hair surface properties, including fatty acid content, deteriorate.

This systematic review and meta-analysis found 30 genetic loci associated with skin ageing phenotypes, noting shared biological pathways in aspects like pigmentation and wrinkling; researchers suggest further studies targeting the same SNP across populations could clarify these associations.

This article discusses a poll presented at the 26th World Congress, but it reports no new research findings.

This review discusses factors affecting hair aging and the current pharmacological treatments for androgenetic alopecia, mentioning topical minoxidil and oral finasteride, but does not present new clinical findings.

This review discusses the potential role of Wnt signaling in aging-related heart diseases and reports no clinical results.

This article highlights the need for dermatologists to understand male-specific anatomical and physiological differences to optimize aesthetic treatment outcomes for men, but it reports no new clinical results.

The study found that aging in hair follicle stem cells leads to hair follicle miniaturization and eventual hair loss in both wild-type mice and humans by proteolyzing type XVII collagen.

This thesis analyzed four skin aging features and their relationships with lifestyle, physiological factors, and genetics.

This research observed that chronological age, rather than hearing loss, primarily affects the auditory cortex in aging, and found that brain aging in PolG mice mirrored that of wild-type counterparts, suggesting differential tissue sensitivity to mitochondrial dysfunction.

This narrative review summarizes evidence on NAD⁺ biosynthesis and turnover, highlighting that while NAD⁺ precursors like NR and NMN consistently boost NAD⁺ levels in preclinical and human studies, clinical outcome results remain varied, indicating a need for more standardized human trials.

This article discusses the effectiveness of fat transfer for facial rejuvenation across all ethnicities, emphasizing its potential as both a primary method and a complement to traditional techniques, but reports no new clinical findings.

This review summarizes how common polymorphisms in androgen and estrogen receptor genes may influence aging-related symptoms and diseases in men, but it reports no new clinical results.

This study found that targeting IL-17 signaling in aged skin reduces inflammation and delays age-related traits, suggesting a potential strategy to prevent age-associated skin ailments.

This study found that communication about aging across seven domains may predict successful aging in Indonesia through both positive and negative effects and efficacy toward aging.

This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.

In this study, recombinant type III collagen was found to promote fibroblast proliferation and migration, suggesting potential anti-aging and repairing effects, although it was only effective in significantly inhibiting IL-6, not TNF-α, secretion.

A genetic mutation linked to longer life and less disease was found in the Amish, and a drug is being developed to replicate these benefits.

This study suggests that the susceptibility of hair follicle melanocytes to oxidative stress as they age may be key in the graying of hair due to reduced catalase expression and activity.

This paper provides an auditable companion package for their exploratory re-analysis of miRNA dysregulation and target enrichment in female pattern hair loss cases, focusing on candidate-level results from a public dataset comparison between affected individuals and healthy controls.

In this study, researchers conducted an exploratory re-analysis of miRNA dysregulation and aging-related target enrichment in female pattern hair loss using data from public GEO dataset GSE106780. The findings are preliminary and should be interpreted as candidate-level results due to the small sample size.

This study identified the transcription factor Elf5 as a novel regulator of keratinocyte proliferation and differentiation in skin, with expression elevated in stem/progenitor cell populations, suggesting its potential role in determining cell fate during skin and hair development.

This case report describes an elderly multiple myeloma patient whose hair repigmentation was associated with lenalidomide use, suggesting hair graying may be reversible.

In this study, researchers found that the interaction between dermal papilla and endothelial cells decreases with age, affecting signaling pathways that promote hair regeneration and angiogenesis in mouse models.