Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This study details how very long human hair naturally ages, showing cuticle wear and internal fiber changes that may inform new hair care product designs.

This study presents a new long-term 3D skin model using cells from mature donor skin, showing significant features of skin aging, such as decreased cellular proliferation and hyaluronan content.

This study found that perifollicular vascularization around the dermal papilla adjusts dynamically to physiological changes, with minoxidil enhancing vessel mobilization and aging processes inhibiting it, highlighting potential targets for treating hair loss and skin aging.

This review details the expression and diverse functions of melatonin receptors in non-neural tissues and reports no new clinical findings, emphasizing their potential as therapeutic targets across various physiological and pathological processes.

This review explores the cellular and molecular basis of wound-induced hair neogenesis and its relationship with aging but does not report new clinical results, highlighting areas for future research.

This review reports on the effects of aging on hair characteristics such as pigmentation, growth, and structural properties across genders and ethnicities, highlighting the importance of scalp health and suggesting cosmetic solutions to improve the appearance of aged hair.

In this study, researchers found that Elastic Net DNA methylation clocks are not accurate for distinguishing between individuals or identifying health markers, but measuring biological "noise" in stable cytosines may serve as a potential biomarker of aging and disease.

This study found that keratin fibers like human hair undergo thermal and mechanical transitions that can help assess changes from cosmetic processes such as bleaching and perm-waving.

This research observed that overexpression of lncRNA H19 in human dermal papilla cells inhibited cell senescence and maintained hair follicle-inducing abilities by activating the Wnt signaling pathway, suggesting potential therapeutic strategies for androgenetic alopecia.

This study presented a reproducibility package supporting an exploratory secondary analysis of miRNA dysregulation and aging-related target enrichment in female pattern hair loss, based on a comparison of three scalp samples from affected women to five healthy controls using public dataset GSE106780.

In this study, researchers conducted an exploratory re-analysis of miRNA dysregulation and aging-related target enrichment using publicly available data on female pattern hair loss, comparing 3 FPHL scalp samples to 5 healthy female controls, and emphasized that the findings are preliminary and require further validation.

This review discusses the effects of estrogen on skin aging and highlights potential therapies, but reports no new clinical findings.

This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.

This study suggests that dermal adipocytes might play a key role in skin aging due to their transformation into fibrotic structures in chronically photo-damaged skin.

This review explores the role of aging-related changes in skin, discussing how impaired skin barrier function may contribute to systemic inflammation, or "inflamm-aging," which in turn could impact the broader decline in organ and tissue function seen in aged individuals.

This review synthesizes recent findings on the hair follicle stem cell niche and its complex interactions, exploring potential pathways for developing new hair growth therapies; it reports no new clinical results.

This article reviews the biological causes and treatment options for facial aging but reports no new clinical findings.

This study found that Si Jun Zi Tang may have anti-aging effects in mice, linked to inhibition of the PI3K-AKT and P38 MAPK signaling pathways.

This review discusses Hutchinson-Gilford progeria syndrome, highlighting its phenotype, pathogenesis, and its potential insights into natural aging and cardiovascular diseases, but it reports no new research findings.

This study concluded that alcohol and tobacco products harm the skin by disrupting microcirculation, impairing the epidermal barrier, slowing wound healing, and accelerating the aging process.

This source discusses the ethical dilemmas and business pressures in cosmetic dermatology, emphasizing the shift toward commercialism and profit-driven practices influenced by social media and market demands, potentially leading to conflicts of interest and professional misconduct.

This study found that decreased COL17α1 expression in aging mouse skin is associated with reduced proliferation of epidermal stem cells and may contribute to thinner epidermis and slower wound healing.

This study found that their novel 3D-imaging method, ASAXA-μCT, identified shrinkage of sweat glands as a key factor in skin aging, which leads to dermal defects, decreased elasticity, and increased wrinkling and sagging.

This review discusses the role of telomere length dynamics in hair follicle biology and reports no new clinical findings, emphasizing the need for further research in humans.

As skin ages, it gets thinner, paler, and more wrinkled, and protection and care like sunblock and moisturizers are important.

This literature review indicates that skin aging involves complex interactions of both internal and external factors, leading to oxidative stress and cellular damage. The authors report promising results from novel anti-aging interventions, including antioxidants, senolytics, and herbal preparations, for slowing skin aging progression.

In this study, researchers found that exosomes derived from dermal sheath cup cells (Exo DSCCs) improved proliferation, viability, and migration while reducing apoptosis in senescent dermal papilla cells, also enhancing hair follicle reconstruction and suggesting a potential strategy for combating senile alopecia.

This report details the development of a PSR™ Terminalia extract with antioxidant and anti-aging potential, highlighting its rich composition in phenolic acids, polysaccharides, and organic acids, without new clinical results.

This review highlights that herbal cosmetics, incorporating modern technologies and traditional knowledge, offer various biological benefits like antioxidant and anti-aging properties. The authors emphasize the need for further clinical validation and standardized manufacturing processes to ensure their long-term safety and effectiveness.

This review discusses the impact of menopause-related oestrogen deficiency on skin ageing and suggests that oestrogen use may improve collagen and skin elasticity, but it reports no clinical trial results.