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Higher hair iron levels are linked to changes in brain structure and function.

This review discusses the anatomy, aging pathophysiology, and various surgical and non-surgical options for rejuvenating the upper face, including antioxidants and non-ablation laser, but reports no new clinical results.

This study identified distinct and diverse fibroblast populations in female scalp cells that lose their signature and identity with age, highlighting significant age-related changes, such as increased fibrosis, DNA damage, and senescence, which may affect scalp dermal support for healthy hair follicles.

Older adults often have skin problems due to aging, and treating these conditions requires attention to both physical and mental health.

This review considers oxidative stress effects on hair aging and emphasizes the need for dermatologists to recognize and treat factors affecting scalp and hair health, but it provides no new clinical findings.

Women's ovarian hormones and adrenal androgens change throughout life, affecting hair loss and health.

This article discusses how the brain's neural circuits evaluate skin aging to judge social standing and suggests that people often attempt to deceive themselves and others about their true age.

This study found that different stressors causing premature senescence in fibroblasts resulted in distinct changes in lipid profiles, particularly sphingolipids, which may affect the behavior of senescent skin cells.

Low dose finasteride causes only minor changes in PSA levels in men over 50 with BPH.

This study highlights multiple factors contributing to hair graying, such as oxidative damage, melanocyte changes, and genetic influences, and suggests that repigmentation may be temporarily reversible, offering potential targets for future treatments while urging caution when applying mouse model findings to humans.

This study examined dermal papilla cells from hair follicles, finding that gene expression changes linked to wound healing and stem cell activity align with hair follicle regression, which could inform strategies for hair growth and skin rejuvenation.

In this descriptive study, elderly patients most commonly presented with skin wrinkling, xerosis, and eczematous conditions, highlighting the difficulty in distinguishing normal age-related from pathological skin changes.

In this pilot study, minoxidil-treated scalp skin grafts from hair loss patients on mice showed increased expression of key anti-aging biomarkers and hair regrowth, suggesting minoxidil as a potential anti-aging agent by boosting VEGF-A production in hair follicles.

Hormones and genetics affect hair growth and patterns, with some changes reversible and others not.

This review discusses the enhanced understanding of how stem cell niches respond adaptively to systemic signals, aging, and local perturbations, but reports no new research findings.

The document concludes that early diagnosis is key for treating common baldness in women, but reassurance is often the best approach as hair thinning can be a normal part of aging.

This study observed that the biophysical properties of hair in Caucasian females with brown hair significantly change with age, and smoking or being overweight was linked to smaller hair cross-sectional areas.

In this study, minoxidil did not demonstrate any anti-aging effects on postconfluent hair follicle cells, as no difference was observed in cell proliferation or differentiation compared to controls.

In this 24-week study, oral supplementation with hydrolyzed low-molecular-weight porcine placental peptides significantly improved scalp elasticity, hair diameter, tensile strength, surface roughness, and luster compared to placebo, suggesting its potential as a nutritional intervention for age-related scalp and hair changes.

This review highlights the importance of implementing dementia screening and cognitive evaluation in primary care to better prepare healthcare providers for managing cognitive impairment in the aging population.

In this study, the deletion of NIPP1 in keratinocytes led to chronic skin inflammation and epidermal changes in mice, with early cell-cycle arrest and premature senescence observed, potentially contributing to reduced mutagen sensitivity.

This study found that a catalytically active version of Vav2 significantly altered gene expression patterns in hair follicle stem cells in mice, with these changes varying over the animals' lifespans.

The book explains causes and treatments for common hair loss, its psychological effects, related health risks, and emphasizes early screening and lifestyle changes.

This study outlines a framework for hair longevity that emphasizes prevention and integrative management of androgenetic alopecia by proposing a multi-targeted approach combining treatments, nutrition, and lifestyle changes.

This review discusses the role of circadian rhythms in stem cell differentiation and tissue regeneration, emphasizing their impact on organ physiology and aging, but reports no new experimental results.

This article reviews the clinical aspects and potential mechanisms of chronic graft vs host disease skin manifestations, describing a novel form of premature skin aging, but presents no new research findings.

This review explores various hormone influences on hair growth and loss beyond androgens, noting that clinical hormone therapies for aging may impact hair due to associated hormone level reductions, but reports no new empirical results.

This paper proposes a theory explaining how the normal anabolic effects of androgens lead to structural changes and hair follicle miniaturization, contributing to androgenic alopecia.

This review discusses the lipid composition of human hair across ethnic types, effects of damage on lipid content, and associated changes with diseases, but reports no new findings; further research is needed.

This article discusses aesthetic concepts in facial volume restoration but reports no new clinical results, highlighting strategies for mimicking natural facial shapes and the importance of highlights and shadows in aging.