29 citations
,
June 2014 in “Drug delivery” This study reported that nanoemulsions significantly improved the skin permeability of thiocolchicoside compared to its aqueous solution, suggesting they are effective carriers for its transdermal delivery.
6 citations
,
December 2022 in “Anais Brasileiros de Dermatologia” 7 citations
,
January 2002 in “Biological Trace Element Research” This study found that children with pituitary dwarfism had higher zinc and copper hair concentrations and lower manganese concentrations compared to healthy children.
15 citations
,
November 2017 in “Drug Development and Industrial Pharmacy” This study found that the optimized finasteride-loaded lyophilized tablets using a self-nanoemulsifying drug delivery system improved bioavailability in human volunteers compared to the marketed finasteride product.
12 citations
,
October 1954 in “Textile Research Journal” This study found that alkali bromide solutions are absorbed into hair depending on salt activity, and the presence of the salt increases water absorption compared to normal conditions.
10 citations
,
March 2005 in “International Journal of Cosmetic Science” This study found that photochemical and cosmetic chemical oxidation of hair causes surface damage by delipidation and acid formation, which can be characterized and quantified using microfluorometry and X-ray photoelectron spectroscopy.
8 citations
,
July 2012 in “Annals of biomedical engineering” This study found that the uptake of molecules by hair is influenced by both hydrophobic and ionic charge interactions, with binding affinity decreasing as pH approaches the solute's dissociation constant.
7 citations
,
January 1981 in “Springer eBooks” This model study describes how interactions between hair keratin and various materials alter hair's physical and mechanical properties by affecting noncovalent bonds.
2 citations
,
March 2018 in “ACS Sustainable Chemistry & Engineering” This study found that stepwise thermal treatment of human hair waste at temperatures from 200 to 450 °C produced hollow microtubes, with structure changes influenced by temperature, core degradation, and cortex melting.
March 2018 in “Vìsnik farmacìï” This study identified flavonoids and phytosterols in a medicated cosmetic cream developed for androgenic alopecia and proposed methods for their identification and quantification.
November 2004 in “Qucosa (Saxon State and University Library Dresden)” This study developed analytical methods to better understand hair treatment with cosmetic formulations, revealing that active agents primarily adsorb on the hair surface during short washes.
38 citations
,
February 2005 in “The journal of sexual medicine” This study found that a testosterone patch and gel showed bioequivalent testosterone levels in hypogonadal men, but the patch mimicked a natural circadian profile, while the gel resulted in higher dihydrotestosterone levels.
15 citations
,
October 2021 in “Frontiers in Pharmacology” This commentary discusses the potential of natural volatiles in medical aromatherapy, highlighting their ability to synergize with other drugs and modulate biological processes, but reports no new results.
9 citations
,
November 2000 in “Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE” This study demonstrated that dyeing can enhance the absorption coefficient of hair follicle tissues for selective photodestruction within human skin and hair follicles.
7 citations
,
April 2021 in “Journal of advanced pharmaceutical technology & research” This study reported that compound 16 (olean-12-en-3beta-ol, cinnamate) from Merremia peltata showed potential as an androgen receptor antagonist, suggesting it may benefit alopecia treatment based on molecular docking and ADME-Tox predictions.
7 citations
,
July 2004 in “International Journal of Cosmetic Science” Different hair types from various ethnic groups affect hair shine due to characteristics like thickness and shape.
5 citations
,
November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” The abstract for Roota Hair Growth describes a product combining botanical extracts with clinically-tested ingredients to target hair thinning, breakage, and scalp fatigue by blocking DHT, strengthening hair fibers, and revitalizing the scalp through a precision roll-on applicator, offering a natural alternative for healthier hair.
Topical corticosteroids are effective for skin conditions but can have side effects.
August 2022 in “International journal of membrane science and technology” This study found that Finasteride may spontaneously diffuse into an SDS-based model cell membrane at a significant rate, with distinct behavior in polar and non-polar solutions.
January 2011 in “Journal of Society of Cosmetic Chemists of Japan” This study found that a conditioner containing 18-MEA and SPDA can improve hair's smoothness and reduce flyaways, enhancing hair manageability.
202 citations
,
June 2005 in “Aaps Pharmscitech” This review discusses the potential of lecithin organogels for improving topical drug delivery and presents no new experimental results; the authors highlight their stability and low skin irritancy as advantages.
130 citations
,
August 2020 in “Drug Design Development and Therapy” This review discusses various nanoparticles used to enhance skin permeation and target delivery to skin organelles, but reports no new experimental results.
48 citations
,
January 2024 in “Frontiers in Pharmacology” This paper reviews strategies to enhance the effectiveness of topical drug delivery by addressing skin barrier challenges, optimizing drug delivery systems, and personalizing treatment approaches, highlighting both current advancements and limitations in the field.
47 citations
,
April 2017 in “European Journal of Pharmaceutics and Biopharmaceutics” This study found that dutasteride-loaded nanostructured lipid carriers coated with a stearic acid-chitosan oligomer are stable, less cytotoxic, and suitable for topical delivery to promote hair growth.
47 citations
,
June 1996 in “International Journal of Legal Medicine” This article discusses how drug molecules integrate into hair fibers, focusing on biological transport mechanisms and physicochemical factors, but reports no new experimental findings.
28 citations
,
December 2010 in “Langmuir” Hair fibers interact through classical forces, which are influenced by treatments and products, important for hair care and other applications.
27 citations
,
September 2018 in “Medicines” This study reported that oleic acid-based nanovesicles improve follicular delivery and reduce side effects of minoxidil compared to traditional MXD lotions.
26 citations
,
May 2012 in “Pharmaceutical Development and Technology” PEVs effectively deliver minoxidil through skin.
17 citations
,
October 2013 in “F1000Research” This case report details a 2-year-old boy who developed generalized hypertrichosis after using 5% minoxidil foam for alopecia areata, highlighting the importance of caution and proper administration instructions for young children.