January 2026 in “Dermatology Research and Practice” This study found that ex vivo, the skin permeability of caffeine increased with formulations using natural caffeine from coffee extract, particularly when combined with 2.5% Transcutol P, compared to synthetic caffeine formulations.
December 2025 in “JEADV Clinical Practice” This review reports that innovative topical treatments for dermatologic conditions like acne and atopic dermatitis show minimal systemic absorption, indicating improved safety and tolerability compared to traditional therapies.
October 2025 in “Clinical Cosmetic and Investigational Dermatology” This study found that hair treated with a supplemental hair care product showed significantly higher absorption, deeper penetration, and reduced dryness compared to untreated and water-treated hair, as measured with 3D Raman spectroscopy.
April 2025 in “American Journal of Case Reports” This case report highlights that improper application techniques, such as scalp occlusion, can increase systemic absorption of minoxidil and lead to unwanted side effects like hypertrichosis.
July 2024 in “Journal of Controlled Release” In this study, researchers developed topical tofacitinib-loaded cationic lipid nanoparticles, which improved absorption and targeted hair follicles in an ex vivo pig ear model, showing promise in treating alopecia areata by reducing symptoms through the JAK/STAT pathway.
June 2021 in “Pharmaceutical sciences” This study found that flutamide emulgels with 1% Transcutol P enhanced percutaneous absorption through rat skin more effectively than other formulations tested.
April 2017 in “Journal of Investigative Dermatology” This study found that retinoic acid and a retinol complex formulation showed different permeation and compound localization in a skin equivalent model, with unique lipid changes observed with only the retinol formulation.
March 1995 in “Proceedings of the British Society of Animal Science” This review discusses zinc's role in dog metabolism and suggests that zinc from amino acid chelates might be better absorbed than from inorganic sources, but reports no new experimental results.
March 1995 in “Proceedings of the British Society of Animal Science” This review discusses zinc's role in dog nutrition, emphasizing that zinc absorption may be improved when provided as an amino acid chelate rather than an inorganic source, but reports no new results.
21 citations
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October 2023 in “The Journal of Physical Chemistry C” This study used theoretical calculations to show that phosphates strongly bind to cerium dioxide surfaces in various stable configurations, with spectral signatures identifiable in the infrared and Raman spectra, informing future experimental efforts in controlling the enzymatic activity of ceria nanoparticles.
42 citations
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January 2007 in “Pediatric dermatology” This report describes an 11-year-old boy with Netherton syndrome who developed Cushing syndrome after using low-potency hydrocortisone ointment extensively, highlighting caution with long-term topical treatments in such conditions.
14 citations
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April 2019 in “Saudi pharmaceutical journal” This study reported that microparticle-loaded emulsions containing caffeic acid achieved more homogeneous distribution and prolonged release in hair follicles, suggesting potential for effective folliculitis treatment.
This review discusses fractionated reirradiation as a potential treatment for recurrent brain tumors in children and highlights ongoing challenges with managing craniospinal dissemination; it provides no new clinical results.
4 citations
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March 2013 in “The American Journal of Cosmetic Surgery” This review discusses how hair follicle light sensitivity is linked to mesenchymal remodeling and suggests that this connection influences photoepilation outcomes and optimal treatment strategies, reporting no new clinical results.
July 2014 in “Zenodo (CERN European Organization for Nuclear Research)” This study observed that low levels of calcium and magnesium in blood serum were associated with health issues like hair loss and anxiety among participants from urban and rural Pakistan.
11 citations
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January 2016 in “International Journal of Biological Macromolecules” This study found that enzymatic phosphorylation of hair keratin increased its capacity to adsorb cationic components like methylene blue and may have practical implications for hair care products.
59 citations
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October 2012 in “Pharmaceutical Research” This study found that nanostructured lipid carriers with more soybean phosphatidylcholine provided better skin retention and follicular targeting for diphencyprone compared to other formulations and controls.
30 citations
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April 1990 in “Clinical Pharmacology & Therapeutics” This study found that coadministering minoxidil with tretinoin cream increased minoxidil absorption nearly threefold in healthy males, attributed to increased stratum corneum permeability.
14 citations
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February 2011 in “Drug Metabolism and Disposition” This study examined the pharmacokinetics of finasteride in pigs and found that ketoconazole coadministration affected its distribution across various plasma compartments, bile, and urine.
8 citations
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January 2021 in “Pharmaceutics” This study found that using nanoporous silica entrapped lipid-drug complexes enhanced the solubility and bioavailability of dutasteride in beagle dogs.
78 citations
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May 2018 in “Plant Soil and Environment” This study found that inoculating tea plants with arbuscular mycorrhizal fungi significantly improved growth, root morphology, and leaf nutrient levels, with Claroideoglomus etunicatum showing the most substantial effects.
25 citations
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June 2015 in “Clinical, Cosmetic and Investigational Dermatology” This study found that using an electrical microneedling device enhanced the penetration of liposomal melanin-fluorescein into hair structures and widened the follicular infundibulum in ex vivo human skin models.
November 2025 in “BMC Urology” This study reports that prostate volume, operation time, resected tissue weight, and smoking increase risks of blood loss and fluid absorption during PK-TURP, while finasteride treatment and surgeon experience may reduce these risks.
January 2022 in “Carolina Digital Repository (University of North Carolina at Chapel Hill)” 41 citations
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May 2012 in “Advanced Healthcare Materials” This study found that human hair keratin coatings enhanced adhesion and proliferation of L929 mouse fibroblasts compared to uncoated and collagen type 1 surfaces, suggesting keratin's potential as a surface coating for cell cultures.
19 citations
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March 1998 in “Microchimica Acta”
11 citations
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December 2020 in “Notulae botanicae Horti Agrobotanici Cluj-Napoca” This study found that arbuscular mycorrhizal fungus inoculation and shading improved tea seedlings' growth, nutrient absorption, and stress resistance by enhancing root biomass and regulating phytohormone levels and gene expression.
May 2025 in “Drug Delivery and Translational Research” January 2005 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” In this study, a 0.5% addition of TPGS to topical minoxidil solutions increased hair growth in mice, but higher concentrations reduced this benefit.