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    Glossary Adipocytes

    specialized cells that store energy as fat

    Adipocytes, also known as fat cells, are specialized cells that store energy in the form of fat. They are found in adipose tissue and play a crucial role in energy metabolism, insulation, and cushioning of organs. Adipocytes can expand or shrink depending on the body's energy balance, and they also secrete hormones and cytokines that influence various physiological processes, including appetite regulation and inflammation.

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    1. Adipocyte Lineage Cells Contribute to the Skin Stem Cell Niche to Drive Hair Cycling Cell · 2011 · 499 citations
    2. Single-cell analysis reveals fibroblast heterogeneity and myeloid-derived adipocyte progenitors in murine skin wounds Nature Communications · 2019 · 301 citations
    3. Epidermal Wnt/β-catenin signaling regulates adipocyte differentiation via secretion of adipogenic factors Proceedings of the National Academy of Sciences of the United States of America · 2014 · 130 citations
    4. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair Cell Stem Cell · 2020 · 124 citations
    5. Adipocytes in Skin Health and Disease Cold Spring Harbor Perspectives in Medicine · 2014 · 77 citations
    6. Hair follicles’ transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog Genes & Development · 2016 · 75 citations
    7. Skin aging: are adipocytes the next target? Aging · 2016 · 70 citations
    8. The Role of Adipocytes in Tissue Regeneration and Stem Cell Niches Annual Review of Cell and Developmental Biology · 2016 · 42 citations
    9. Cutaneous consequences of inhibiting EGF receptor signaling in vivo: Normal hair follicle development, but retarded hair cycle induction and inhibition of adipocyte growth in EgfrWa5 mice Journal of Dermatological Science · 2010 · 32 citations
    10. SCA-1+ Cells with an Adipocyte Phenotype in Neonatal Mouse Skin Journal of Investigative Dermatology · 2005 · 28 citations
    11. The metabolic syndrome- associated small G protein ARL15 plays a role in adipocyte differentiation and adiponectin secretion Scientific Reports · 2017 · 23 citations
    12. Repeal and Replace: Adipocyte Regeneration in Wound Repair Cell Stem Cell · 2017 · 22 citations
    13. Bone vs. fat: Embryonic origin of progenitors determines response to androgen in adipocytes and osteoblasts Bone · 2011 · 22 citations
    14. A guide to studying human dermal adipocytes in situ Experimental Dermatology · 2018 · 21 citations
    15. Inhibitory Effects of Apple Polyphenols on Differentiation of 3T3-L1 Cells into Adipocytes. Food Science and Technology Research · 2000 · 18 citations
    16. Adipocyte-Derived Stem and Regenerative Cells in Facial Rejuvenation Clinics in Plastic Surgery · 2012 · 14 citations
    17. Ethyl acetate fraction of Eclipta alba: a potential phytopharmaceutical targeting adipocyte differentiation Biomedicine & Pharmacotherapy · 2017 · 13 citations
    18. Dihydrotestosterone, and Not Testosterone, Enhances the LPS-Induced Inflammatory Cytokine Gene Expression in Human Adipocytes Biomedicines · 2023 · 7 citations
    19. PDGFA regulation of dermal adipocyte stem cells Stem cell investigation · 2017 · 3 citations
    20. Neural, adipocyte and hepatic differentiation potential of primary and secondary hair follicle stem cells isolated from Arbas Cashmere goats BMC veterinary research · 2022 · 2 citations
    21. 974 Single-cell analysis identifies heterogeneity of fibroblasts and myeloid-derived adipocytes in regenerating mouse skin wounds 2019 · 1 citations
    22. Deletion of adipocyte Sine Oculis Homeobox Homolog 1 prevents lipolysis and attenuates skin fibrosis 2024
    23. 743 Adipocyte stem cells are maintained by Pdgfα signaling in the skin Journal of Investigative Dermatology · 2016
    24. Adipocyte-Derived Amino Acid Storage Proteins are Required for Germline Stem Cell Maintenance in Adult <i>Drosophila</i> Females 2025
    25. AB1159 HIGH FAT DIET AND THE ADIPOCYTE TO MYOFIBROBLAST TRANSITION: IMPLICATIONS FOR SYSTEMIC SCLEROSIS CUTANEOUS FIBROSIS 2024
    26. Regulation of adipocyte dedifferentiation at the skin wound edge bioRxiv (Cold Spring Harbor Laboratory) · 2023
    27. 976 Knockout of mTOR/Akt inhibitor REDD1 results in hair cycle-independent dermal adipose expansion by promoting adipocyte differentiation Journal of Investigative Dermatology · 2019
    28. Epidermal Wnt/beta-catenin signalling promotes dermal adipocyte differentiation during hair follicle morphogenesis and regeneration Journal of Dermatological Science · 2012
    29. A review of adipocyte lineage cells and dermal papilla cells in hair follicle regeneration Journal of Tissue Engineering · 2014 · 35 citations
    30. Adipocytic Progenitor Cells Give Rise to Pathogenic Myofibroblasts: Adipocyte-to-Mesenchymal Transition and Its Emerging Role in Fibrosis in Multiple Organs Current Rheumatology Reports · 2020 · 33 citations