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Aminopterin was somewhat effective in acute lymphoblastic leukemia in children but did not increase survival time.

Advanced hydrogel systems with therapeutic agents could greatly improve acute and chronic wound treatment.

Accidentally eating a topical steroid may rarely cause acute generalized pustular psoriasis.

RV3466F lotion significantly reduces hair loss and improves acute telogen effluvium.

5-alpha reductase inhibitors slightly reduce urinary symptoms and may lower surgery and acute retention risks in men.

Ionizing radiation causes irreversible skin damage, with single doses leading to acute injury and hair graying, and fractional doses causing more severe long-term tissue damage.

A woman's hair loss after COVID-19 was likely due to a mix of pressure-induced alopecia and acute telogen effluvium.

Long-haul COVID can cause lasting symptoms affecting many body systems and may be linked to ongoing inflammation and immune system issues.

Some drugs can cause rare but potentially deadly skin reactions, and early treatment and avoiding the drug again are key.

Drugs that block DHT production can effectively treat enlarged prostate and improve urinary issues with some sexual side effects.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Patients with certain skin symptoms and high ANA titers should be monitored for potential systemic lupus.

Most people with systemic lupus erythematosus have skin problems, and skin symptoms are often the first sign of the disease.

Lupus affects the body and skin, causing joint pain and skin issues that can be treated with steroids and antimalarial drugs.

Generalized pustular psoriasis patients often need strong medication and careful treatment due to flare-ups and complications.

In Italian patients with lupus, the most common skin issue was chronic cutaneous lupus, especially discoid lesions, and nonspecific skin problems occurred in about a third of those with systemic lupus, mainly during active disease.

Survivors of Stevens-Johnson syndrome/toxic epidermal necrolysis need ongoing care for various long-term health problems.

The document concludes that skin biopsies, genetic and environmental factors, and specific treatments are important in managing cutaneous lupus erythematosus.

Chronic Telogen Effluvium may resolve after years and is diagnosed by examining the patient's history and clinical signs, with treatment aimed at underlying causes and possibly minoxidil.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

Sunlight worsens hair loss; protect scalp.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

HIV can cause various severe or unusual skin conditions that help indicate the presence and stage of the disease.

The CLASI is a reliable tool for measuring the severity of cutaneous lupus erythematosus.

Activin A helps heal skin wounds and protects the brain after injury.

COVID-19 infection may cause significant hair loss, but full hair recovery is likely without special treatment.

Metformin is effective for various skin disorders but may cause skin side effects.

Black dots under trichoscopy can appear in different hair and scalp conditions, not just in alopecia areata.

Stress and alcohol affect brain chemicals differently in rats, mice, and humans, influenced by genetic differences.