3 citations
,
November 2021 in “IntechOpen eBooks” This chapter reviews the role of the testes in producing and functioning of testicular androgens and protein hormones, but it presents no new clinical results.
1 citations
,
October 2022 in “International journal of endocrinology” This study found that dihydrotestosterone treatment in female rats altered anterior pituitary gland gene expression, with significant repression of prolactin and inhibition of GnRH receptor gene expression, suggesting specific hormone production changes.
January 2017 in “Springer eBooks” Understanding genes and hormones is crucial for managing male puberty and sex development disorders.
71 citations
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November 2005 in “The journal of investigative dermatology. Symposium proceedings/The Journal of investigative dermatology symposium proceedings” This review discusses the role of Edar signaling in hair follicle development and cycling, emphasizing its impact on cell fate, differentiation, and interactions with other pathways, but reports no new results.
29 citations
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March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” This study observed that isoproterenol directs hair-follicle-associated pluripotent stem cells to differentiate into cardiac muscle cells in large numbers, forming tissue sheets of beating heart muscle cells in culture.
January 2024 in “PloS one” This study found that rat hair-follicle-associated pluripotent stem cells can be successfully differentiated into beating atrial and ventricular cardiomyocytes by using specific combinations of growth factors and inhibitors in culture, demonstrating their potential to form functional myocardial fibers similar to adult heart cells.
This study observed that activin A and its antagonist follistatin influence the differentiation of inner ear hair cells by regulating the expression of the transcription factor ATOH1.
August 2017 in “Journal of Investigative Dermatology” Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
January 2007 in “The Year book of dermatology” Researchers successfully isolated and identified key stem cells in human hair follicles, which could help develop new skin and hair treatments.
January 2004 in “Enshou saisei” This study observed that follistatin and activin interactions significantly influence hair follicle development in mice, suggesting potential regenerative treatments for alopecia.
January 2026 in “European Journal of Dermatology” This article examines the use of legal amphetamines by French political figures from the Liberation to the 1960s, highlighting their impact on health and their prevalence among Communist activists, influenced by habits from the Resistance.
14 citations
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February 2000 in “Feminism & Psychology” This article discusses PCOS's limited public and feminist awareness and highlights the stress experienced by women with hirsutism, but presents no new research findings.
13 citations
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November 2005 in “Endocrinology” This study explored the secretion and cellular localization of different forms of follistatin and FST-like-3, revealing variable secretion kinetics and possible intracellular roles, particularly for nuclear FSTL3.
5 citations
,
November 2024 in “Advanced Science” This study reported the establishment of a chemically defined culture system that supports tooth reconstitution and detailed how co-stimulation of specific signaling pathways can sustain tooth development stages and initiate enamel formation, providing insights into tooth regeneration mechanisms.
245 citations
,
January 2018 in “Bone Research” This review discusses the role of TGF-β signaling in stem cell recruitment and tissue regeneration, indicating that abnormalities in TGF-β activation contribute to various major diseases and suggesting avenues for therapeutic intervention.
156 citations
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December 2012 in “Cell Stem Cell” This review explores the role of TGF-β superfamily pathways in stem cell environments and their implications for tissue regeneration and cancer development, reporting no new experimental results.
28 citations
,
July 2008 in “Developmental Biology” This study found that the loss of Smad4 in keratinocytes reduces Dsg4 expression via disrupted BMP signaling, contributing to hair follicle degeneration and alopecia.
20 citations
,
August 2014 in “PloS one” This study found that MED1 deficiency in keratinocytes accelerates skin wound healing in young mice but delays healing in older mice, suggesting differential roles in epidermal regeneration with age.
6 citations
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January 2013 in “Chemical & pharmaceutical bulletin/Chemical and pharmaceutical bulletin” In this study, TASP0382088 showed potent selective inhibition of the ALK5 receptor, significantly reducing Smad2 phosphorylation in mouse skin following topical application.
5 citations
,
January 2005 in “Cytotherapy” This meeting in Heidelberg highlighted diverse contributions on stem cell research, including pre-clinical and clinical applications, but reported no new experimental results.
October 2022 in “Southeast Asian journal of health professionals” This article discusses factors influencing hair greying, such as thyroid hormone levels and postmenopausal changes, and suggests lifestyle adjustments for hair health; it reports no new clinical findings.
March 2014 in “Journal of The American Academy of Dermatology” The document lists various dermatology topics, treatments, and diagnostic methods.
85 citations
,
March 2002 in “Body & Society” This article reviews the discourse around male cosmetic surgery patients and argues against the perception that cosmetic surgery will become as common among men as it is among women.
27 citations
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April 2017 in “British Journal of Dermatology” This study identified overexpression of certain immune-related genes and underexpression of genes in specific signaling pathways in premature androgenetic alopecia, suggesting potential new therapeutic targets.
21 citations
,
December 2016 in “PLOS ONE” This study developed a new protocol to efficiently produce skin dermal stem cells from human induced pluripotent stem cells, which may aid in treating various skin disorders.
6 citations
,
September 2019 in “Archives of Dermatological Research” In this study, researchers identified 32 differentially expressed genes involved in androgenetic alopecia, with down-regulated genes associated with Wnt and TGF-beta signaling and up-regulated genes linked to oxidative stress pathways.
2 citations
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July 2021 in “Journal of The European Academy of Dermatology and Venereology” This review examines skin conditions found in notable world leaders post-World War II and discusses their potential impacts on political life, reporting no new clinical findings.
1 citations
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June 2013 in “Clinics in dermatology” This review discusses various phytochemicals with potential antialopecia properties and their modes of action, reporting no new experimental results.
April 2024 in “International Journal of Advanced Multidisciplinary Research and Studies” This study outlines a multidisciplinary approach to investigate primary amenorrhea, emphasizing the necessity to consider medical history, physical examination, and potential hormonal or anatomical causes, and recommends early referral in cases of chromosomal abnormalities or persistent amenorrhea following the development of secondary sexual characteristics.
January 2021 in “Journal of cosmetology & trichology” This study suggests that L-(+)-Tartaric Acid may support hair growth by up-regulating certain genes in human Dermal Papilla cells, making it a potentially useful additive in minoxidil formulations.