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This study highlights that dermatologists should be aware of the cultural norms of hair care in adolescents of color with textured hair, as these practices can influence acne distribution and treatment.

This case report describes an 18-year-old male whose acne, unresponsive to traditional treatments and only partially improved with oral isotretinoin, was linked to androgen metabolism anomalies indicative of a non-classical form of congenital adrenal hyperplasia.

This review outlines the complex factors involved in acne pathogenesis—including hormonal, genetic, and environmental influences—and describes current comprehensive management strategies, emphasizing both topical and systemic therapies, while also highlighting emerging treatment options and the significant psychological impact of acne.

In this study, researchers isolated gram-positive bacteria from acne lesions in 50 patients, finding that Staphylococcus epidermidis, Staphylococcus aureus, Micrococcus luteus, and Leuconostoc mesenteroides were present at varying frequencies, indicating multimicrobial causes for acne vulgaris.

This study identified 18 significant metabolites and two enriched metabolic pathways, necroptosis and ABC transporters, in serum samples of acne patients with and without insulin resistance, potentially aiding in the clinical diagnosis and drug development for these patients.

This study found that the prevalence of polycystic ovarian morphology is high among women aged 21-45 with acne and/or androgenic alopecia, especially in those with combined dermatological symptoms.

This study found that isotretinoin decreases mTORC1 signaling in acne skin, suggesting that mTOR inhibitors may have potential therapeutic benefits for acne patients.

This study found that while nicotinic acid significantly inhibited human sebaceous organoid growth in vitro, the predicted skin concentrations from gut microbiome-derived levels were far below the effective dose, suggesting high oral doses would be necessary for therapeutic effects.

In this article, the authors detail their experience with AltrenoTM, a new topical retinoid lotion used for treating mild to moderate acne, reporting clinical effectiveness and satisfactory tolerability among patients of various ages, including children as young as 9.

This study found that mTOR gene expression was significantly higher in individuals with acne vulgaris compared to healthy controls, suggesting its potential as a biomarker for acne prognosis and treatment response.

This study suggests that increased levels of ischemia-modified albumin, indicating oxidative stress, are associated with greater severity of acne vulgaris.

This study found that clinical and biochemical markers of hyperandrogenism were more common in post-adolescent and early adult-onset acne among women than in adolescent acne.

This study found shared genetic pathways linking acne with multiple mental health disorders and observed a potential causal relationship between acne and increased depression risk.

This review discusses the possible roles of skin and intestinal microbiota in acne pathogenesis and covers related research on traditional Chinese medicine treatments, without reporting new clinical results.

This article reviews current acne treatments linked to polycystic ovary syndrome in adults but reports no new clinical findings.

This study found that both oxidant and antioxidant levels were elevated in acne patients, suggesting that oxidative stress may be linked to acne pathogenesis but its causal role remains unclear.

This study found that BEO inhibited cell proliferation and inflammatory mediator release in a human keratinocyte acne model and reduced acne lesion severity in a rabbit model, suggesting its potential as a natural alternative to conventional acne treatments.

This article discusses the mechanisms by which Cutibacterium acnes contributes to acne vulgaris and mentions potential triggers like UV light and tobacco, but it reports no new clinical results.

This article discusses Ayurvedic perspectives on acne vulgaris and outlines potential natural remedies, but it presents no new clinical findings.

This study found that one-third of females with acne and PCOS also showed insulin resistance, suggesting that women with these conditions should be evaluated for impaired glucose tolerance.

This study found that hormonal abnormalities are not very common in adult females with acne, although some patients showed indicators of hyperandrogenism.

This review emphasizes the importance of endocrinologic evaluation in acne patients due to its association with endocrine disorders like hyperandrogenism; it reports no new clinical results.

This study found that patients with acne vulgaris had significantly higher serum levels of betatrophin compared to healthy controls, suggesting it may be an independent predictor of acne severity and vulnerability.

This study observed that patients with acne vulgaris had significantly lower serum vaspin levels and higher insulin resistance, suggesting a potential role of vaspin in the disease's pathogenesis.

This study investigates whether adding 30% supramolecular salicylic acid to conventional treatment for mild to moderate acne vulgaris is safe and effective, though specific results are not reported in the abstract.

This trial explores whether spironolactone is more effective than cyclines for treating moderate acne in adult women, providing a potential alternative amidst concerns over antibiotic resistance.

This case report emphasizes the importance of recognizing non-classic congenital adrenal hyperplasia as a cause of hyperandrogenism and the need for genetic counseling given potential familial implications.

This study found that adult acne predominantly affects females, with persistent acne being common, and noted a low prevalence of PCOS among female adult acne patients.

This study developed two types of polymeric nanoparticles containing clindamycin phosphate for potential topical acne treatment and found that the NP-AH-CDM-4 formulation preferentially penetrated hair follicles even with sebaceous obstruction, suggesting its promise for more effective acne therapy without causing skin irritation.

This study found that certain dietary changes, such as a low glycemic load diet for men and specific supplements for women, may improve acne, while chocolate, whey proteins, and dairy products are linked to worsened symptoms in both genders.