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    Did you mean Acetylcholinesterase?
    Glossary Acetylcholinesterase

    breaks down acetylcholine in the synaptic cleft

    Acetylcholinesterase (AChE) is an enzyme that breaks down the neurotransmitter acetylcholine in the synaptic cleft, which is the space between nerve cells. This process is crucial for terminating nerve impulses and allowing muscles to relax after contraction. Inhibiting AChE can lead to prolonged muscle contraction and is a mechanism used by certain nerve agents and pesticides.

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    Research 30 of 183

    1. Finasteride Has Regionally Different Effects on Brain Oxidative Stress and Acetylcholinesterase Activity in Acute Thioacetamide-Induced Hepatic Encephalopathy in Rats PLOS ONE · 2015 · 11 citations
    2. Development and Validation of an HPLC-PDA Method for Quantitation of Ten Marker Compounds from Eclipta prostrata (L.) and Evaluation of Their Protein Tyrosine Phosphatase 1B, α-Glucosidase, and Acetylcholinesterase Inhibitory Activities Natural Product Sciences · 2020 · 4 citations
    3. The effects of finasteride (FIN) and thioacetamide (TAA) on acetylcholinesterase (AchE) activity in various brain regions. PLOS ONE · 2015
    4. Anti-acetylcholinesterase and Antioxidant Effects of Identified Compounds from Houttuynia cordata The Korean Tea Society · 2022
    5. Phytochemical profiling, green synthesis of Ag, Cu, Fe, and Zn nanoparticles, and in vitro biological activities of Delphinium brunonianum Royle Scientific Reports · 2026
    6. Enzyme Inhibitory Activities of Marine Sponges Against Cholinesterase and 5α-Reductase 2019
    7. Angelica gigas Nakai (Korean Dang-gui) Root Alcoholic Extracts in Health Promotion and Disease Therapy – active Phytochemicals and In Vivo Molecular Targets Pharmaceutical Research · 2025 · 2 citations
    8. GC–MS Profiling, Antioxidant, Enzyme Inhibition, Molecular Docking, and ADME Investigation of the <i>n</i> ‐Hexane Extract and the Essential Oil of <i>Platycladus orientalis</i> (L.) Franco Fruits Chemistry & Biodiversity · 2026
    9. Antioxidant and Cholinesterase Inhibitory Activity of a New Peptide From <i>Ziziphus jujuba</i> Fruits American Journal of Alzheimer s Disease & Other Dementias® · 2013 · 69 citations
    10. Caffeic Acid attenuates acrylamide induced biochemical, hematological and histological alterations in rats Research Square (Research Square) · 2022
    11. Baiting Proteins with C<sub>60</sub> ACS Nano · 2010 · 106 citations
    12. EFFECT OF ECLIPTA ALBA ON SCOPOLAMINE INDUCED AMNESIA IN MICE Journal of Drug Delivery and Therapeutics · 2018 · 5 citations
    13. Assessment of the Chemical Profile and Potential Medical Effects of a Flavonoid-Rich Extract of Eclipta prostrata L. Collected in the Central Highlands of Vietnam Pharmaceuticals · 2023 · 6 citations
    14. Pharmacological Efficacy of Tamarix aphylla: A Comprehensive Review Plants · 2021 · 20 citations
    15. PEGylated Flavonoid Aspasomes as a Brain-Targeted Nano-Vesicular Platform for Enhanced Neuroprotection in Stress-Induced Cognitive Dysfunction AAPS PharmSciTech · 2026
    16. Evaluation of Hair Growth Activity of Buxus wallichiana Baill Extract in Rats Iranian Journal of Basic Medical Sciences · 2009 · 3 citations
    17. Current Perspectives on the Physiological Activities of Fermented Soybean-Derived Cheonggukjang International Journal of Molecular Sciences · 2021 · 26 citations
    18. Essential Oil and Important Activities of<i>Thuja orientalis</i>and<i>Thuja occidentalis</i> Journal of Essential Oil Bearing Plants · 2015 · 15 citations
    19. A REVIEW ON THE PHARMACOLOGICAL ACTIVITIES OF THUJA ORIENTALIS L. Science and Culture · 2024
    20. Chemistry, biological activities and toxic effects of alkaloidal constituents of genus Delphinium - A mini review Journal of Herbmed Pharmacology · 2021 · 11 citations
    21. Antiparasitic efficacy of geraniol from Apiaceae family in scabies treatment Scientific Reports · 2025
    22. PVA/Agar based films reinforced with pickering emulsion of Achillea millefolium L. essential oil Gümüşhane Üniversitesi Fen Bilimleri Enstitüsü Dergisi · 2026
    23. Novel Synthetic Steroid Derivatives: Target Prediction and Biological Evaluation of Antiandrogenic Activity Current Issues in Molecular Biology · 2025
    24. Synthesis and biological activity evaluation of new isatin-gallate hybrids as antioxidant and anticancer agents (in vitro) and in silico study as anticancer agents and coronavirus inhibitors Pharmacia · 2024 · 3 citations
    25. Juniperus sabina L. as a Source of Podophyllotoxins: Extraction Optimization and Anticholinesterase Activities International Journal of Molecular Sciences · 2022 · 16 citations
    26. Therapeutic potential of Ishophloroglucin a from Ishige okamurae in androgenic alopecia: inhibition of 5α-reductase activity and activation of the Wnt/β-catenin signaling pathway in human dermal papilla cells Applied Biological Chemistry · 2026
    27. Acquired Localized Hypertrichosis Induced by Rivastigmine Case reports in dermatological medicine · 2016 · 3 citations
    28. Neurobehavioral protective properties of curcumin against the mercury chloride treated mice offspring Saudi Journal of Biological Sciences · 2018 · 27 citations
    29. A network pharmacology-based approach to explore mechanism of action of medicinal herbs for alopecia treatment Scientific Reports · 2022 · 8 citations
    30. Green approach for the recovery of secondary metabolites from the roots of Nardostachys Jatamansi (D. Don) DC using microwave radiations: Process optimization and anti-alzheimer evaluation Frontiers in Plant Science · 2022 · 3 citations