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Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.

Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.

Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.

New compounds were made that block an enzyme linked to breast cancer better than existing treatments.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Liver enzyme helps minoxidil work better for blood vessel relaxation.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Mice with human gene experienced hair loss when treated with DHT.

Rutin may help treat symptoms of polycystic ovary syndrome (PCOS) in rats.

Androgen is important in controlling stem cell differentiation, reducing fat development, and increasing lean mass.

Non-coding RNAs play key roles in the hair growth cycle of Angora rabbits.

Loss of keratin K2 causes skin problems and inflammation.

The document concludes that treating tough skin disease in lupus involves sun protection, steroids, antimalarials, and various other therapies chosen based on individual risks and benefits.

New method detects finasteride in plasma quickly and accurately without clean-up.

DNA methylation changes are linked to hair growth cycles in goats.

DNA methylation and long non-coding RNAs are key in controlling hair growth in Cashmere goats.

St. John's Wort extract and oil safety in cosmetics is unclear; more data needed on photosensitization, toxicity, and human irritation.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Obese and non-obese women with PCOS have higher heart risk markers, especially if they are obese.

Certain changes to the B-ring of androgen receptor ligands can increase their effectiveness for potential treatments of muscle and bone conditions.

Thyroid receptor agonists may treat male pattern baldness without harmful side effects.

Adding a small amount of TPGS to minoxidil can help hair growth, but too much TPGS reduces this effect and increases minoxidil in the blood.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Scientists found new, better-working inhibitors for a hormone-related enzyme.

Wnt7a protein is crucial for development and tissue maintenance and plays varying roles in diseases and potential treatments.