February 2023 in “Molecules” Cactus extract from Notocactus ottonis may help promote hair growth.
January 2023 in “International Journal of Molecular Sciences” Maxillariinae orchids contain 62 compounds with potential health benefits, including treating skin conditions and diseases like cancer and diabetes.
September 2018 in “Practical diabetes” Sodium valproate is not recommended as a first-line treatment for neuropathy but may be used in resistant cases.
January 2008 in “US endocrinology” Mutations in the glucocorticoid receptor gene cause reduced sensitivity to glucocorticoids and may lead to poor response to treatment.
January 2022 in “Stem cell biology and regenerative medicine” Improving dermal papilla cells can help regenerate hair follicles.
January 2020 in “International Journal of Applied Biology and P” Finasteride treatment for three years changes certain polyamine levels in the blood but not in urine.
178 citations,
May 2006 in “Developmental Dynamics” Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
3 citations,
April 1989 in “Drug Information Journal” Side effects of drugs can lead to the discovery of new treatments.
9 citations,
June 2014 in “Nutrition and Cancer” Eclipta alba extract may work as an anticancer agent and help reverse drug resistance.
Any medication can cause skin reactions, some due to allergies and others due to dosage or genetic factors.
51 citations,
April 1982 in “Lancet” Most patients with hard-to-treat high blood pressure can be managed effectively with various treatments, but no single treatment is perfect.
16 citations,
May 1982 in “Postgraduate Medical Journal” Minoxidil can cause pericardial and pleural effusions with high protein content.
11 citations,
July 2020 in “International Journal of Ayurvedic Medicine” Indigofera tinctoria leaf extract has many compounds that support its traditional medicinal uses.
11 citations,
April 2009 in “Pharmacotherapy” Minoxidil can cause deadly skin reaction; monitor patients closely.
5 citations,
June 2011 in “Bioorganic & Medicinal Chemistry Letters” New Finasteride conjugate improves prostate treatment and vital signs in rats.
February 2023 in “Asian journal of pharmaceutical research and development” Flavonoids in Iraqi marshland plants have potential health benefits like antioxidant and anti-inflammatory effects.
The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.
343 citations,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
237 citations,
February 2016 in “Science Translational Medicine” The timing of when the gene Bmal1 is active affects aging and survival, with its absence during development, not adulthood, leading to premature aging.
135 citations,
December 2015 in “Expert Opinion on Biological Therapy” Exosomes could potentially enhance tissue repair and regeneration with lower rejection risk and easier production than live cell therapies.
112 citations,
January 2014 in “Molecular and cellular therapies” Blocking the Wnt pathway could lead to new treatments for cancer and tissue repair but requires careful development to avoid side effects.
111 citations,
August 2002 in “Journal of Medicinal Chemistry” New compounds were made that block an enzyme linked to breast cancer better than existing treatments.
76 citations,
November 2009 in “Medical Clinics of North America” Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.
68 citations,
September 1990 in “Biochemical Pharmacology” Minoxidil activates hair growth by being sulfated by P-PST in the human liver.
66 citations,
September 1982 in “Biochemical Pharmacology” Liver enzyme helps minoxidil work better for blood vessel relaxation.
59 citations,
May 2017 in “Scientific reports” ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.
53 citations,
June 2012 in “Annales d'Endocrinologie” The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.
53 citations,
January 1993 in “Biochemical Pharmacology” Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.
48 citations,
July 1996 in “Human & Experimental Toxicology” Human enzymes can detoxify harmful substances but might also increase their cancer risk.
42 citations,
March 2010 in “Endocrinology” Mice with human gene experienced hair loss when treated with DHT.