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Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Women with PCOS should be screened for heart disease risk and manage their health to prevent it.

Polycystic Ovary Syndrome likely starts in childhood and may be genetic and influenced by early hormone exposure.

Insulin sensitizers may slightly reduce hirsutism but are less effective than other treatments.

Spironolactone most effective for hirsutism, but has side effects.

The document concludes that accurate measurement of serum androgens is crucial for diagnosing hyperandrogenism.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.

Androgens like testosterone affect hair growth and oil production differently across body parts and individuals.

Some plant-derived compounds may help with hormonal conditions, but more research is needed to confirm their effectiveness.

The exact cause of increased 5α-reductase activity leading to hirsutism in women is still unknown.

Finasteride reduces hair growth and is safe for women with excessive hair.

Testosterone therapy may slightly improve sexual function in postmenopausal women, but its long-term safety is unknown.

New compounds may soon be tested to treat excessive hair growth in women.

The document says that understanding the causes of PCOS is important for treatment, especially in distinguishing the syndrome from just having cystic ovaries, and that losing weight is key for obese women with PCOS.

Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.

Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.

Metformin improved menstrual cycle regularity and signs of hyperandrogenism in adolescent girls with type 1 diabetes but did not improve blood sugar control.

Medications for PCOS don't seem to raise heart disease risk.

Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.

Androgen replacement therapy can improve libido and mood in women with severe androgen deficiency, but more research is needed on its long-term safety.

A new gene mutation causes insulin resistance in a girl and her mother.

The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.

Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.

Hormone treatments in transsexual individuals reduce hair growth and oil production in male-to-females and increase them in female-to-males.

Antiandrogens are somewhat effective in reducing excessive hair growth in women.

The research found that Atypical Progeroid Syndrome has unique symptoms and is not caused by the buildup of a certain mutant protein.

Testosterone replacement may help some postmenopausal women with symptoms like fatigue and low libido, but more research is needed to fully understand its effects.

A new gene mutation causes female pseudohermaphroditism due to glucocorticoid resistance.