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Oral retinoids can cause side effects ranging from mild to severe, including birth defects, and require careful monitoring and contraception.

High androgen levels in Chinese women with PCOS are linked to a higher risk of diabetes and obesity.

Mutations in the hairless gene in mice affect its expression and lead to a range of developmental issues in multiple tissues.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.

Polycystic Ovary Syndrome is common but often undiagnosed, and early treatment is important to prevent health problems.

Noncoding dsRNA boosts hair growth by activating TLR3 and increasing retinoic acid.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

The LRRK2-G2019S mutation in Parkinson's disease has a lifetime penetrance of 25-35%, and finasteride may help reduce symptoms in adult male Tourette syndrome patients.

Finasteride reduces Tourette syndrome symptoms, but results may be limited due to potential biases.

Disrupting Acvr1b in mice causes severe hair loss and thicker skin.

Hair loss treatments include medications and new methods like low-level light therapy, which may work by boosting cell activity and blood flow.

Mice lacking Insig proteins had hair growth problems due to cholesterol buildup, but this was fixed by the drug simvastatin.

Silicon can improve skin and hair health, but more research is needed.

Genetic variations affecting skin structure play a key role in severe acne.

Genetic mutations can cause hair growth disorders by affecting key genes and signaling pathways.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.

The document concludes that correct diagnosis and management of PCOS are important, and more research is needed on its risks and treatments.

No systemic treatment for alopecia areata has strong evidence of effectiveness.

Psoriasis can cause temporary or permanent hair loss.

A woman's total hair loss from hepatitis C treatment grew back after stopping the medication.

The French Endocrine Society suggests diagnosing PCOS with two of three signs, recommends lifestyle changes and clomiphene for treatment, and calls for more research on certain treatments and tests.

Systemic glucocorticosteroids are a primary treatment for various skin conditions but require careful management due to potential side effects and relapses.

Different lab conditions and light treatment methods change how human skin cells respond to light therapy.

Finasteride may help reduce symptoms in male Tourette syndrome patients.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

The document suggests that clinical trials for PCOS should focus on meaningful primary outcomes like live birth rates, rather than less reliable surrogate markers.

A simplified scoring system can effectively diagnose hirsutism in Chinese women of reproductive age.

Hair follicle hyperplasia is common in both benign and malignant skin lymphoproliferative disorders, with a proposed new term "pseudolymphomatous adnexitis."