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Testosterone therapy seems safe for postmenopausal women for a few years, but more research is needed for long-term effects.

Lichen Planopilaris and Frontal Fibrosing Alopecia may help us understand hair follicle stem cell disorders and suggest new treatments.

Spironolactone effectively reduces hair growth in women with hirsutism and is generally well-tolerated.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Hormonal treatments can help with acne but are not the first choice due to side effects and the need for careful patient selection.

Hormones, especially androgens, play a key role in acne, which can be a symptom of systemic diseases like PCOS and may require targeted treatment.

The conclusion is that certain scalp tissue changes are characteristic of lichen planopilaris, with mucinous perifollicular fibroplasia being a new feature for diagnosis.

Progress has been made in skin and nerve regeneration, but more research is needed to improve methods and ensure safety.

Young men with male pattern baldness lose hair density over time without treatment.

Men with coeliac disease may have hormone imbalances that could affect sexual function, but these can improve with better gut health.

Shrinking skin cancer increases the chance of cancer in nearby lymph nodes.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Androgens cause skin issues like acne and hair growth in women, often due to PCOS, and can be treated with medication and lifestyle changes.

Androgen receptors are key for development and health, affecting conditions like prostate cancer and male pattern baldness.

The document concludes that early recognition and treatment of primary cicatricial alopecia is crucial to prevent permanent hair loss.

Dermatologists play a key role in treating skin symptoms of PCOS like dark patches, excess hair, acne, and hair loss.

The article explains the genetic causes and symptoms of various hair disorders and highlights the need for more research to find treatments.

The current methods for diagnosing polycystic ovary syndrome are too vague and may lead to misdiagnosis and problems in research.

SHBG may be a useful early indicator and treatment target for PCOS.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Improving the environment and cell interactions is key for creating human hair in the lab.

The document concludes that while there are various treatments for Alopecia Areata, there is no cure, and individualized treatment plans are essential due to varying effectiveness.

Drugs targeting the JAK/STAT pathway can improve atopic dermatitis but vary in effectiveness for vitiligo and alopecia areata, with generally mild safety concerns.

Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.

Malnutrition severely harms growth and development in young baboons.

Women with PCOS often have more body hair, acne, and skin darkening, and these signs are linked to metabolic issues like insulin resistance and high cholesterol.

People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.

Alopecia common in teens, may indicate endocrine issue, minoxidil effective treatment.