This study observed two distinct groups of alopecia areata lesions based on PD-1 expression in T cells from biopsied skin samples, suggesting potential differences in subtypes or stages of the disease that warrant further investigation.
April 2023 in “Journal of Investigative Dermatology” This study found that in biopsied skin samples of alopecia areata, a lower anagen/telogen ratio was associated with increased T cell infiltration, and enhancing the PD-1/PD-L1 axis may inhibit CD8+T cell infiltration and improve the condition.
55 citations
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March 1990 in “The Journal of Clinical Endocrinology and Metabolism” This study found that finasteride decreased plasma dihydrotestosterone levels and altered steroid metabolism, similar to the profile of male pseudohermaphrodites with inherited 5a-reductase deficiency.
9 citations
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January 2017 in “Ginekologia Polska” This study found that the total testosterone/dihydrotestosterone ratio correlates with a negative metabolic profile in both women with PCOS and healthy women.
18 citations
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November 2016 in “Transgenic research” This study found that transgenic cashmere goats overexpressing thymosin beta-4 have a higher secondary to primary hair follicle ratio, suggesting potential for increased cashmere yield.
18 citations
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June 1998 in “Circulation” This letter discusses how outdated measurement technology may obscure evidence of essential fatty acid deficiency in low-fat diet patients, potentially leading to undiagnosed EFA insufficiencies related to heart disease.
January 2024 in “Journal of Natural Remedies” This study found that the petroleum ether extract of Solanum nigrum may promote hair regrowth in testosterone-induced hair loss in rats, as indicated by increased follicle density and anagen/telogen ratio.
December 2023 in “International journal of research in dermatology” This study found that using 'moha: 5-in-1' hair oil for 8 weeks significantly reduced hair fall, increased hair growth rate and thickness, and decreased scalp dandruff among healthy adults with alopecia, with no adverse effects reported.
In this open-label study, the researchers observed that using Kerascalp hair serum daily for 90 days improved hair thickness, density, and strength while reducing hair loss in subjects with mild to moderate androgenetic alopecia, with benefits persisting even after discontinuation.
January 2021 in “International journal of pharmaceutical research” In this study, the researchers found that the ethyl acetate fraction of Sansevieria trifasciata P. (20%) was just as effective as minoxidil (2%) in promoting hair growth in male rabbits, with notable results in hair follicle proliferation and a favorable anagen to telogen ratio.
October 2020 in “International Journal of Research in Dermatology” In this study, adding platelet-rich plasma to minoxidil and finasteride treatment for patterned hair loss improved hair outcomes with minimal side effects compared to using minoxidil and finasteride alone.
March 2014 in “Journal of The American Academy of Dermatology” A botanical extract may help manage hair loss from chemotherapy by preventing cell death in hair follicles.
April 2013 in “Cancer Research” This study found that a botanical extract increased Bcl-2 levels and improved the anagen-to-telogen hair ratio in men with androgenetic alopecia, suggesting potential for managing chemotherapy-induced alopecia.
In this study, Minoxidil and other treatments prevented alopecia in mice induced by Paclitaxel, with quantitative data supporting the inhibition of hair loss.
40 citations
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June 2009 in “Journal of Cutaneous Pathology” This study found that Iranian patients with androgenetic alopecia had a higher terminal to vellus hair ratio compared to previous studies in Whites, suggesting potential onset of miniaturization.
30 citations
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April 2011 in “Rapid communications in mass spectrometry/RCM. Rapid communications in mass spectrometry” This study found that using hair steroid profiling, dutasteride treatment led to reduced dihydrotestosterone levels and DHT/testosterone ratio in patients with male-pattern baldness.
103 citations
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June 2006 in “British journal of sports medicine” This review discusses the use of anabolic-androgenic steroids in sports and outlines current methods for detecting urinary steroid doping, particularly testosterone, but reports no new experimental findings.
28 citations
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April 2014 in “Hormones” This study found that increased serum A4A levels were associated with more severe polycystic ovary syndrome phenotypes and could be a useful marker for biochemical hyperandrogenemia.
21 citations
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November 2010 in “Talanta” This study reported the development of a novel and reliable liquid chromatographic method to measure testosterone and epitestosterone in human urine, offering sensitive detection for doping control.
20 citations
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August 2009 in “Journal of The European Academy of Dermatology and Venereology” This study found that the occipital scalp is significantly involved in female pattern hair loss, with some patients showing clinically visible alopecia.
12 citations
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June 2006 in “British Journal of Sports Medicine” This article reviews the history and current medicolegal challenges of doping in sports, focusing on FIFA's procedures and three urgent legal issues, but presents no new findings.
7 citations
,
March 2020 in “Journal of King Saud University. Science/Maǧallaẗ ǧāmiʹaẗ al-malik Saʹūd. al-ʹUlūm” This study found that AiQingHua oil improved microcirculation and promoted hair regeneration in mice with testosterone-induced alopecia.
4 citations
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August 2020 in “Facial plastic surgery & aesthetic medicine” This study found that combining concentrated growth factor injections with minoxidil treatment significantly improved hair growth and participant satisfaction in male patients with androgenetic alopecia compared to minoxidil alone.
4 citations
,
June 2003 in “Fertility and Sterility” In this pilot study, finasteride increased testosterone/dihydrotestosterone and progesterone/dihydroprogesterone ratios in normal ovulatory women but did not alter ovulation or gonadotropin secretion.
This study found that trichoscopy is an effective method for monitoring treatment response in androgenetic alopecia when conducted by doctors experienced in hair diseases, showing excellent agreement with TrichoScan measurements for various hair parameters.
December 2022 in “JEADV Clinical Practice” In this study, researchers found that using a handheld digital microscope, hair diameter was a better determinant of perceived alopecia severity in androgenetic alopecia than hair density.
January 2013 in “Medical & Pharmaceutical Journal of Chinese People's Liberation Army” In this study, catgut embedding combined with moxibustion and bloodletting was reported to be more effective than finasteride for androgenetic alopecia, reducing hormonal imbalances and improving patient quality of life.
August 1987 in “European journal of endocrinology” This study found no correlation between plasma androgen levels and androgenetic alopecia in women, suggesting that increased androgen action may not be reflected in these parameters.
18 citations
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August 2012 in “Chinese journal of integrative medicine/Chinese Journal of Integrative Medicine” This study reported that total glucosides of paeony capsules were as effective and safe as compound glycyrrhizin tablets for treating mild to moderate alopecia areata.
5 citations
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November 2017 in “Dermatologica Sinica” In this study, transverse sectioning of scalp biopsy samples showed higher diagnostic accuracy than vertical sectioning for noncicatricial alopecia, although both techniques are important for accurate diagnosis.