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DHT, a testosterone byproduct, causes male pattern baldness.

Biotin supplements improved skin and hair problems in a girl with biotinidase deficiency.

Too much Smad7 changes skin and hair development by breaking down a protein called β-catenin, leading to more oil glands and fewer hair follicles.

The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.

Smad4 is important for healthy hair follicles because it helps produce a protein needed for hair to stick together and grow.

New and known mutations in the hairless gene cause a hair loss condition called Atrichia with papular lesions.

Plant roots respond to fungus smells by possibly using certain proteins and a plant hormone to change root growth, but more research is needed.

Hair follicles in the back of the rosette fancy mouse have reversed orientations due to a gene mutation.

Finasteride and dutasteride are effective for long-term treatment of enlarged prostates but have sexual side effects and a risk of high-grade prostate cancer.

The document concludes that while some organisms can regenerate body parts, mammals generally cannot, and cancer progression is complex, involving mutations rather than a strict stem cell hierarchy.

Different types of stem cells exist within individual skin layers, and they can adapt to damage, transplantation, or tumor growth. These cells are regulated by their environment and genetic factors. Tumor growth is driven by expanding, genetically altered cells, not long-lived mutant stem cells. There's evidence of cancer stem cells in skin tumors. Other cells, bacteria, and genetic factors help maintain balance and contribute to disease progression. A method for growing mini organs from single cells has been developed.

A Gsdma3 mutation causes hair loss due to stem cell damage from skin inflammation.

A gene variant increases the risk of a type of hair loss by affecting hair protein production.

A special receptor in sensory nerve endings helps control how they respond to stretching.

Calcineurin inhibitors, used in kidney transplants, can cause a wide range of side effects including kidney damage and other health issues.

A specific RNA, circNlgn, contributes to heart damage and scarring caused by the cancer drug doxorubicin.

The TRPV3 ion channel is important for skin and hair health and could be a target for treating skin conditions.

Certain immune-related proteins are higher in people with alopecia and their healthy relatives, hinting at a genetic link.

A specific gene variant is linked to heart disease, increased heart muscle, curly hair, and thick skin on palms and soles.

A new tool can analyze hair to detect changes due to hormones, genetics, and aging.

Enzymes involved in Vitamin A metabolism affect hair growth and type in mice.

A man with both Klinefelter syndrome and primary hyperparathyroidism showed a rare combination of symptoms and genetic patterns.

Celiac disease requires more than just a gluten-free diet for effective management.

Hair patterns in mice are controlled by both a global system dependent on Fz6 and a local self-organizing system.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

The we/we wal/wal mice have defects in hair growth and skin layer formation, causing hair loss, useful for understanding alopecia.

Women look young for their age due to larger lips, less sun damage, and genes that prevent gray hair and wrinkles.

Nellore cattle have genetic variations linked to their adaptation to tropical environments.

Hair follicle regeneration may slow tumor growth.

Lower zinc levels may predict less effective hair loss treatment.