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    Glossary Melatonin

    hormone regulating sleep-wake cycles, produced by pineal gland

    Melatonin is a hormone produced by the pineal gland in the brain that regulates sleep-wake cycles. It is often used as a supplement to treat sleep disorders and jet lag, as it helps signal to the body that it is time to sleep.

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    1. Melatonin membrane receptors in peripheral tissues: Distribution and functions Molecular and Cellular Endocrinology · 2012 · 506 citations
    2. The cutaneous serotoninergic/melatoninergic system: securing a place under the sun ˜The œFASEB journal · 2005 · 349 citations
    3. Melatonin in the skin: synthesis, metabolism and functions Trends in Endocrinology and Metabolism · 2008 · 252 citations
    4. Serotoninergic and melatoninergic systems are fully expressed in human skin ˜The œFASEB journal · 2002 · 249 citations
    5. On the Role of Melatonin in Skin Physiology and Pathology Endocrine journal · 2005 · 222 citations
    6. MELATONIN Clinical endocrinology · 1988 · 220 citations
    7. Melatonin: A Cutaneous Perspective on its Production, Metabolism, and Functions Journal of Investigative Dermatology · 2018 · 185 citations
    8. Melatonin: functions and ligands Drug discovery today · 2014 · 160 citations
    9. Melatonin as a major skin protectant: from free radical scavenging to DNA damage repair Experimental dermatology · 2008 · 160 citations
    10. Hair Color, Molt, and Testis Size in Male, Short-Tailed Weasels Treated with Melatonin Science · 1969 · 133 citations
    11. A role of melatonin in neuroectodermal‐mesodermal interactions: the hair follicle synthesizes melatonin and expresses functional melatonin receptors ˜The œFASEB journal · 2005 · 122 citations
    12. Melatonin and the hair follicle Journal of pineal research · 2007 · 109 citations
    13. Effects of Melatonin Supplementation on Hormonal, Inflammatory, Genetic, and Oxidative Stress Parameters in Women With Polycystic Ovary Syndrome Frontiers in Endocrinology · 2019 · 81 citations
    14. Melatonin increases anagen hair rate in women with androgenetic alopecia or diffuse alopecia: results of a pilot randomized controlled trial British Journal of Dermatology · 2004 · 78 citations
    15. Mechanism of Sleep Disturbance in Children with Atopic Dermatitis and the Role of the Circadian Rhythm and Melatonin International Journal of Molecular Sciences · 2016 · 63 citations
    16. Murine skin as a target for melatonin bioregulation Experimental dermatology · 1994 · 57 citations
    17. Growth of secondary hair follicles of the Cashmere goat in vitro and their response to prolactin and melatonin. PubMed · 1994 · 56 citations
    18. INTERACTION OF α-MELANOCYTE-STIMULATING HORMONE, MELATONIN, CYCLIC AMP AND CYCLIC GMP IN THE CONTROL OF MELANOGENESIS IN HAIR FOLLICLE MELANOCYTES IN VITRO Journal of Endocrinology · 1981 · 53 citations
    19. Ultrastructural evaluation of the radioprotective effects of melatonin against X‐ray‐induced skin damage in Albino rats International journal of experimental pathology · 2005 · 52 citations
    20. Adrenal steroid hormone concentrations in dogs with hair cycle arrest (Alopecia X) before and during treatment with melatonin and mitotane Veterinary dermatology · 2004 · 52 citations
    21. Effect of constant-release melatonin implants and prolonged exposure to a long day photoperiod on prolactin secretion and hair growth in mouflon (Ovis gmelini musimon) Domestic animal endocrinology · 2004 · 51 citations
    22. Fiber growth initiation in hair follicles of goats treated with melatonin 1993 · 48 citations
    23. Effects of maintaining solstice light and temperature on reproductive activity, coat growth, plasma prolactin and melatonin in goats Reproduction · 1999 · 47 citations
    24. Melatonin promotes secondary hair follicle development of early postnatal cashmere goat and improves cashmere quantity and quality by enhancing antioxidant capacity and suppressing apoptosis Journal of Pineal Research · 2019 · 46 citations
    25. Clinical cosmeceutical repurposing of melatonin in androgenic alopecia using nanostructured lipid carriers prepared with antioxidant oils Expert Opinion on Drug Delivery · 2018 · 46 citations
    26. Effects of melatonin administration on mental health parameters, metabolic and genetic profiles in women with polycystic ovary syndrome: A randomized, double-blind, placebo-controlled trial Journal of Affective Disorders · 2019 · 45 citations
    27. Protective Effects of Melatonin on the Skin: Future Perspectives International Journal of Molecular Sciences · 2019 · 44 citations
    28. Protective effects of melatonin against metabolic and reproductive disturbances in polycystic ovary syndrome in rats Journal of Pharmacy and Pharmacology · 2014 · 41 citations
    29. Melatonin vitamin C-based nanovesicles for treatment of androgenic alopecia: Design, characterization and clinical appraisal European Journal of Pharmaceutical Sciences · 2018 · 40 citations
    30. Topical Melatonin for Treatment of Androgenetic Alopecia International Journal of Trichology · 2012 · 39 citations