16 citations
,
May 2015 in “Tissue Engineering Part C-methods” This study found that expanding hair follicle keratinocytes with a fibroblast feeder followed by short-term coculture with dermal papilla cells could restore their ability to form new hair follicles.
16 citations
,
July 2008 in “BMC Genomics” This study shows that alpha 6 + /MHCI - cells have gene expression profiles similar to hair follicle stem cells, suggesting they may be enriched for stem cells.
15 citations
,
June 2011 in “Journal of Investigative Dermatology” This study found that overexpressing the 14-3-3σ protein in transgenic mice reduced keratinocyte proliferation and migration, leading to thinner epidermis and fewer hair follicles due to IGF-1 pathway inhibition.
8 citations
,
February 2025 in “Cell Systems” This study developed a genetic toolbox to engineer Cutibacterium acnes for dermal applications, successfully creating a strain that secretes antioxidants to reduce oxidative stress in a UV stress model.
8 citations
,
August 2021 in “Computational and Mathematical Methods in Medicine” This article proposes a machine learning framework for classifying healthy hair and alopecia areata using image processing and classification techniques, but does not report new clinical findings.
7 citations
,
January 2024 in “Cancer Research Communications” This study found that TAp63 and ΔNp63 isoforms in the p63 family interact with different transcription factors to regulate distinct transcriptional programs, affecting various biological functions like metabolic pathways, oxidative stress response, and epithelial morphogenesis in mouse epidermal cells.
6 citations
,
December 2021 in “Journal of Clinical Medicine” This study introduced the Lichen Planus Activity and Damage Index (LiPADI), which effectively assesses the severity and progression of lichen planus, aligning well with other clinical indicators.
6 citations
,
February 2021 in “Advances in Clinical and Experimental Medicine” In this study, patients with alopecia areata received a single intradermal injection of Wharton's jelly-derived mesenchymal stem cells, resulting in an average hair regrowth of 67% at treated sites within 24 weeks, demonstrating both efficacy and safety without side effects.
3 citations
,
November 2022 in “Experimental dermatology” This article discusses melatonin's role in mammalian coat color and its potential in melanoma treatment when used with chemotherapy, but reports no new clinical results.
3 citations
,
January 2020 in “Journal of Cutaneous and Aesthetic Surgery” This review highlighted that despite existing treatments, chronic nonhealing leg ulcers remain a significant therapeutic challenge, necessitating the development of new methods that are effective, safe, and affordable for patients.
3 citations
,
January 2017 in “Journal of cardiovascular pharmacology” This article discusses the challenges in hypertension management, emphasizing the need to reconsider the use of minoxidil and address excess dietary sodium and arteriolar hypertrophy, but reports no new clinical results.
2 citations
,
November 2023 in “Biomolecules” This review article analyzes the role of the WNT signaling pathway in skin development, wound healing, and mechanical stretching, emphasizing its importance in understanding and potentially advancing treatments for skin-related diseases.
2 citations
,
June 2022 in “Cosmoderma” This review discusses regenerative medicine's applications in dermatology, highlighting the need for quality clinical trials to optimize treatments like PRP, stem cells, and exosomes, and reports no new results.
2 citations
,
September 2014 in “The American Journal of Cosmetic Surgery” This review discusses advancements and challenges in laboratory-based tissue-expansion and transplantation techniques for facial wound healing, noting potential for stem cell therapies but highlighting the ongoing absence of skin features like hair follicles in cultured grafts.
2 citations
,
January 2006 in “Indian Journal of Veterinary Pathology” In this study of sheep across various breeds and ages, researchers found that Trichophyton mentagrophytes caused severe dermatophytosis, especially affecting young Shahbadi sheep during winter, leading to notable anemia and skin lesions.
1 citations
,
March 2024 in “Science” In this study, researchers found that retinoic acid is crucial for hair follicle stem cell function and tissue regeneration by resolving lineage plasticity, with potential therapeutic implications for hair growth, wound healing, and cancer.
1 citations
,
March 2022 in “IntechOpen eBooks” This article reviews the functions and locations of skin stem cells and their role in regeneration and differentiation, relating age-associated skin changes to decreased stem cell functionality; it reports no new experimental findings.
1 citations
,
October 2015 in “Journal of endocrinology and diabetes” This review discusses the diagnostic criteria and challenges in recognizing polycystic ovary syndrome, noting varied phenotypes and the absence of consensus on renaming the condition; it reports no new findings.
1 citations
,
January 2012 in “International journal of trichology” This study found that keratinocytes derived from the germinative epithelium of ovine hair follicles have extensive in vitro growth potential, challenging the idea that these cells are solely transit-amplifying.
August 2024 in “Current Issues in Molecular Biology” In this study, researchers analyzed skin tissue from two sheep breeds during the growing period and identified 56 differentially expressed lncRNAs and 616 mRNAs linked to hair follicle development, suggesting potential targets for improving sheep wool quality through genetic and molecular approaches.
January 2024 in “Biochemical genetics” This study investigated the gene and protein expression differences in early and late feathering chickens, identifying several pathways, like JAK-STAT and WNT, potentially involved in non-Mendelian feather growth regulation.
August 2023 in “International Journal of Molecular Sciences” This review discusses the use of human-to-mouse xenografting to study human skin processes in vivo, highlighting its importance for understanding skin regeneration and pathology while identifying knowledge gaps and challenges in applying these findings to human skin.
35 citations
,
January 2022 in “Clinical Infectious Diseases” This study found that healthcare workers with a positive COVID-19 test reported long COVID symptoms more frequently than negative controls, while prior physical activity was linked to reduced neurocognitive and fatigue symptoms.
32 citations
,
September 2018 in “Journal of pharmaceutical sciences” This study extended a skin diffusion model to include a porous pathway, effectively explaining the permeability of both polar and lipophilic solutes through the stratum corneum.
December 2025 in “Molecules” This study developed a method using UHPLC-MS/MS and MSPE to detect trace amounts of sex hormones in cosmetics, finding progestins and estrogens in some products, and performed a preliminary safety evaluation for residual progesterone in hair loss prevention cosmetics.
1 citations
,
February 2026 in “ACS Omega” This review highlights the potential of self-powered nanogenerators in revolutionizing biomedical devices by using biomechanical or environmental energy, focusing on applications like regenerative hair growth, drug release patches, and electronic skin while evaluating challenges such as energy efficiency and biocompatibility.
Treatments for hair loss vary, but cell-based options may be the future.
5 citations
,
January 2004 in “Biochimie” This review discusses arsenic trioxide therapy in acute promyelocytic leukemia and introduces a novel method using hair analysis to monitor arsenic exposure and correlate it with treatment timing, but reports no new clinical results.
2 citations
,
April 2007 in “arXiv (Cornell University)” This study describes a follicular automaton model that simulates human hair cycles and may replicate hair pattern evolution seen in diffuse or androgenetic alopecia.
February 2024 in “International journal of biology, pharmacy and allied sciences” This review discusses the potential of plant-based preparations for treating hair loss and reports no new clinical results; the authors highlight herbs with evidence of efficacy against alopecia.