8 citations
,
January 1996 in “Springer eBooks” This article discusses the minimal research on hair growth physiology and highlights Dr. Masumi Inaba's contributions to understanding androgenetic alopecia, but reports no new experimental results.
2 citations
,
August 2024 in “Indian Dermatology Online Journal” Premature graying of hair is mainly caused by genetics, stress, and environment, with potential treatments being explored.
1 citations
,
February 2025 in “International Journal of Molecular Sciences” This study found that an enzymatic digestion method for isolating hair follicle stem cells from scalp specimens yielded 5.3 times more epithelial cells than explant cultures, while supporting comparable cell functionality, offering a promising technique for tissue engineering and regenerative medicine.
March 2025 in “Pakistan Journal of Scientific & Industrial Research Series A Physical Sciences” This abstract discusses the challenges of diagnosing and managing PCOS, highlighting that individualized management, lifestyle modifications, and medical treatments such as contraceptives and metformin are recommended to address hormonal imbalances and co-morbidities.
December 2013 in “Research Portal (King's College London)” This article discusses the anatomical and biological aspects of hair follicle stem cells in the bulge region but reports no new research findings.
4 citations
,
January 2009 in “Acta agriculturae Serbica” This study observed that both excessive and deficient selenium levels in a C57BL/6 mouse model were associated with hair loss and changes in hair follicles, likely due to alterations in the hair follicle cycle and increased apoptosis.
2 citations
,
May 2024 in “European journal of medical research” This study found that a conditioned medium from human umbilical cord mesenchymal stem cells cultured in a gelatin sponge significantly enhanced hair growth and promoted skin angiogenesis in a mouse model, more effectively than a monolayer culture.
62 citations
,
June 1993 in “Archives of Dermatological Research” 74 citations
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October 2023 in “Nature Reviews Molecular Cell Biology” January 1989 in “Handbook of experimental pharmacology” This review discusses the impact of drugs on human hair growth, highlighting its psychological importance and noting that most contributions are from clinical perspectives, with some input from biochemists and physiologists.
13 citations
,
February 2007 in “Biotechnology and Bioprocess Engineering” 104 citations
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July 1994 in “The Journal of Cell Biology” This study suggests that basonuclin in keratinocytes is likely a regulatory molecule linked to maintaining proliferative capacity and preventing terminal differentiation rather than a cell cycle marker.
2 citations
,
May 2015 in “International Journal of Scientific Reports” In this observational study, 95% of androgenetic alopecia patients treated with neonatal mesenchymal stem cells through mesotherapy showed mild to moderate improvement in hair growth and reduction in hair loss.
97 citations
,
June 2013 in “Journal of Dermatological Science” This review discusses the role of the EGF receptor/ligand system in skin homeostasis and its implications for keratinocyte stem cells and reports no new clinical results.
March 2024 in “Tissue and cell/Tissue & cell” This study found that in human hair bulbs, telomerase is present mainly in the nuclei of cells undergoing proliferation, particularly in the matrix epithelium during the anagen phase, and sparsely in the outer root sheath during late catagen and telogen phases.
45 citations
,
August 2018 in “Stem Cells International” This article reviews the potential of adipose-derived and Wharton’s jelly stem cells in alopecia treatment but presents no new clinical findings, highlighting their potential benefits and limitations in regenerative medicine.
4 citations
,
March 2022 in “Pharmaceutics” This review explores regenerative treatment options for non-scarring alopecia, with a focus on the potential of mesenchymal stem cells for hair regrowth, but it reports no new clinical results.
2 citations
,
January 2017 in “AIMS cell and tissue engineering” This review discusses the potential of mesenchymal stem cell therapies for treating various skin diseases, including vitiligo, alopecia, and epidermolysis bullosa, but reports no new results.
45 citations
,
August 2018 in “Haematologica” This study found that iron retention in macrophages impairs hair follicle growth and delays wound healing in mice, highlighting the importance of macrophage iron release for skin health.
2 citations
,
March 2025 in “Industrial Crops and Products” This study found that peach kernel oil extracted via supercritical fluid extraction had higher quality and antioxidant properties than oil obtained by other methods, effectively protecting human hair follicle keratinocytes from oxidative damage.
426 citations
,
August 2014 in “Nature Medicine” This narrative review examines the interactions between skin stem cells and their niches, finding new insights from advancements in genetic and imaging tools but reporting no new experimental results.
207 citations
,
July 2006 in “Development” This study identified a novel MTS24-positive murine keratinocyte population with increased colony-forming ability, suggesting these cells may serve as a new reservoir of proliferative progenitor or stem cells in hair follicles.
91 citations
,
June 2011 in “The EMBO Journal” This study demonstrates that hair follicle bulge stem cells can transition into other stem cell compartments, indicating their role in maintaining both hair follicles and sebaceous glands.
77 citations
,
April 2005 in “Journal of Investigative Dermatology” Repetin is a protein involved in skin and hair development, binding calcium and compensating for other proteins when needed.
44 citations
,
July 2020 in “Stem Cell Research & Therapy” This review discusses recent advancements in the study and application of epidermal stem cells for wound healing and tissue engineering, without presenting new experimental findings.
38 citations
,
April 2016 in “The Journal of Pathology” This study found that mice lacking alkaline ceramidase 1 with elevated skin ceramide levels showed disrupted skin homeostasis, including altered hair follicle structures, increased water loss, and a hypermetabolism phenotype.
36 citations
,
April 2010 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that canine bulge-derived keratinocytes are highly proliferative and can reconstitute pilosebaceous structures, indicating their potential utility in studying human stem cell biology and hair disorders.
20 citations
,
September 2004 in “Journal of Anatomy” This study suggests that the structure and function of the inner root sheath in mammalian hair may have evolved from simpler forms seen in monotremes, aiding in hair exit without damaging the epidermis.
18 citations
,
July 2012 in “Cell Biology International Reports” This study suggests that human mesenchymal stem cells have the potential to differentiate into dermal papilla cells both in vitro and in vivo.
17 citations
,
September 2016 in “Stem cells translational medicine” In this study, using stirred-suspension bioreactors to expand dermal stem cells resulted in larger numbers, but had reduced efficiency in forming hair follicle structures compared to static culture conditions.