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Glioblastoma cells can make androgens, which might help the tumor grow.

Male hormones and their receptors play a key role in hair loss and skin health, with potential new treatments being explored.

Using 5-alpha reductase inhibitors may increase the risk of mild depression.

Both drugs lower DHT levels, with GI198745 being more effective.

Activating TSPO helps protect the retina from damage caused by high eye pressure in glaucoma.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Dutasteride protects dopamine neurons in Parkinson's mice, but Finasteride doesn't.

Neurosteroids can influence behavior by modulating brain inhibition, with potential for treating psychiatric disorders.

A new anti-baldness patch effectively treats hair loss by blocking enzymes linked to the condition.

Ficus benghalensis leaf extracts can effectively promote hair growth and inhibit hair loss.

The leaves of Platycladus orientalis have potential health benefits but require more research for safety and understanding how they work.

Chitrak is a medicinal plant with health benefits like fighting microbes, reducing inflammation, and promoting hair growth, but it can be toxic and needs more research.

Dutasteride, usually used for prostate issues and hair loss, could potentially treat Amyotrophic Lateral Sclerosis (ALS) due to its neuroprotective, antioxidant, and anti-inflammatory properties, but more testing is needed.

Saw palmetto extract reduced hair loss and improved hair growth in people with hair thinning.

Melandrium firmum extract helps mice grow hair by blocking a hair loss enzyme and changing hair growth genes.

Mouse hair cells respond to male hormones by growing less, and this can be stopped by certain blockers.

LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Male pattern baldness involves genetics, hormones, and needs better treatments.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

The conclusion is that we need more effective hair loss treatments than the current ones, and these could include new drugs, gene and stem cell therapy, hormones, and scalp cooling, but they all need thorough safety testing.

Many potential alopecia treatments need more testing to confirm they promote acceptable hair growth with minimal side effects.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Acne significantly affects mental health and quality of life, with research suggesting hormonal and genetic factors in its development and emphasizing early treatment to prevent scarring.

Laser hair removal is safe and effective for fair-skinned people with dark hair, and using eflornithine with laser treatments can improve results.

Men with early balding showed higher levels of certain genes linked to hair loss and possibly prostate cancer.

Urologic diseases and treatments in older men can negatively affect fertility, and doctors should talk to patients about this.

The current understanding of frontal fibrosing alopecia involves immune, genetic, hormonal factors, and possibly environmental triggers, but more research is needed for effective treatments.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.

Understanding how hair follicle stem cells work can help find new ways to prevent hair loss and promote hair growth.