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Different animals have unique versions of the enzyme that changes testosterone into another hormone, which is important for creating effective treatments for prostate and hair loss conditions.

Finasteride treats enlarged prostate and hair loss, but may cause side effects in some patients.

Finasteride treatment changes brain steroid levels and receptors, affecting brain function even after stopping treatment.

Androgen conjugates might be better indicators of skin sensitivity to hormones in women with excessive hair growth.

Some hair loss and prostate drugs might increase the risk of diabetes and heart disease.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Blocking 5α-reductase can harm memory and brain structure, and increase harmful brain changes in male mice used for Alzheimer's disease research.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

High-dose dutasteride reduces PMDD symptoms by stabilizing neurosteroid levels.

Certain steroids in the brain affect mood and symptoms of depression, and treatments targeting these steroids show promise for improving these symptoms.

Post-finasteride syndrome causes lasting sexual, neurological, and physical side effects in some people after taking finasteride.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Current research explores hair growth drugs, while future research aims for personalized treatments.

5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Too much androgen can cause hair loss; finasteride may help.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Probe detects finasteride with high selectivity and low detection limit.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

MENT could be a better option than testosterone for male hormone therapy and birth control because it works well at lower doses and has fewer side effects on the prostate.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Neuroactive steroids may affect the risk and treatment of alcohol use disorders.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Male hormones are important for hair and oil gland development and can cause conditions like excessive hair growth and acne.

Baldness caused by male hormones in female-to-male transsexuals doesn't increase the risk of heart disease.

Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.

Men with testicular cancer were less likely to experience baldness and severe acne.