research Relation of Urinary Stone Disease with Androgenetic Alopecia and Serum Testosterone Levels
Balding and low testosterone increase risk of urinary stones.
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research Techniques for the Discovery and Evaluation of Drugs Against Alopecia
We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
research Rat Steroid 5α-Reductase Kinetic Characteristics: Extreme pH-Dependency of the Type II Isozyme in Prostate and Epididymis Homogenates
The activity of a specific rat enzyme in the prostate and epididymis is highly dependent on the acidity level.
research Effect of the 5α-Reductase Enzyme Inhibitor Dutasteride in the Brain of Intact and Parkinsonian Mice
Dutasteride may protect the brain in early Parkinson's disease.
research 5α-Reductase Activity in the Prostate
Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.
research The Rationale for Inhibiting 5α-Reductase Isoenzymes in the Prevention and Treatment of Prostate Cancer
Inhibiting 5α-reductase can help reduce prostate cancer risk and improve treatment.
research 5α-Reductase Inhibitors and Prostatic Disease
5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.
research Effect of Testosterone Supplementation With and Without a Dual 5α-Reductase Inhibitor on Fat-Free Mass in Men With Suppressed Testosterone Production
Testosterone's muscle-building effects do not require its conversion to DHT.
research Role of 5α-Reductase in Health and Disease
5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.
research 5α-Reductase Inhibitors in the Treatment of Androgenetic Alopecia
Finasteride improves hair growth in men with androgenetic alopecia.
research Analytical Methods of Dutasteride: An Overview
Dutasteride is more effective than finasteride for hair loss treatment.
research Serenoa Repens and N-Acetyl Glucosamine/Milk Proteins Complex Differentially Affect the Paracrine Communication Between Endothelial and Follicle Dermal Papilla Cells
Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.
research Dutasteride
Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
research 46,XY DSD Due to Impaired Androgen Production
Impaired androgen production in 46,XY DSDs causes ambiguous genitalia and requires long-term care.
research Finasteride-Induced Gynecomastia in a 62-Year-Old Man
Finasteride caused enlarged breast tissue in a 62-year-old man.
research The Effect of Plasma Rich in Growth Factors on Pattern Hair Loss: A Pilot Study
Treatment with plasma rich in growth factors improved hair density and thickness for hair loss patients.
research Infertility and Teratogenicity After Paternal Exposure to Systemic Dermatologic Medications: A Systematic Review
Some skin medications can harm male fertility, but they don't seem to cause birth defects from father's exposure.
research Is Seborrhea a Sign of Autonomic Impairment in Parkinson's Disease?
Seborrhea in Parkinson's disease may be linked to hormones, not autonomic impairment.
research Polycystic Ovary Syndrome: An Endocrine Disorder
PCOS is a hormonal disorder causing infertility and menstrual problems, often linked to obesity and can lead to acne, treated with hormonal and insulin-sensitizing medications.
research Hair Replacement Surgery for Male Pattern Alopecia
Surgical hair replacement is a viable option for male pattern baldness when done with proper planning and realistic expectations.
research Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride
Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.
research Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss
Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.
research Hirsutism: Evaluation and Treatment
Excessive hair growth can be assessed by history, exam, and blood tests, and treated with medication like dexamethasone, birth control pills, and spironolactone.
research Post-Finasteride Syndrome – Does It Really Exist?
Post-finasteride syndrome's existence is uncertain; more research needed.
research Testosterone: The Male Sex Hormone
More research is needed to understand how testosterone is maintained in adult males.
research Four-Amino Acid Segment in Steroid 5 Alpha-Reductase 1 Confers Sensitivity to Finasteride, a Competitive Inhibitor
Four-amino acid part makes enzyme sensitive to finasteride.
research Synthesis and In Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-Oxo-4-Androstene-17β-Carboxamides as 5α-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach
New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.
research Overexpression of Aldo-Keto Reductase 1C3 in LNCaP Cells Diverts Androgen Metabolism Towards Testosterone Resulting in Resistance to the 5α-Reductase Inhibitor Finasteride
Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
research 5α-Metabolism in Finasteride-Treated Subjects and Male Pseudohermaphrodites with Inherited 5α-Reductase Deficiency
Finasteride lowers DHT levels and raises testosterone in a dose-dependent way.