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Finasteride treatment in rats changed the expression of genes related to psychiatric and neurological functions, and these changes persisted after stopping the drug.

MC4R gene variants not linked to female hair loss.

Blocking CRF-R1 can reduce alcohol intake in stressed mice.

Finasteride can cause lasting sexual, emotional, and cognitive issues, with varying severity.

NTF gel improves finasteride delivery for hair loss treatment, reducing side effects.

Need better hair loss treatments beyond minoxidil, finasteride, and transplants.

Finasteride given to baby rats causes anxiety-like behavior and worsens learning from punishment in adult rats.

Alternative treatments show promise for hair growth beyond traditional methods.

Some treatments for hair loss, like finasteride, biotin, and minoxidil, can be effective, but their success varies by individual case.

Finasteride might affect memory by impacting cholinergic system.

The new rodent model successfully mimics non-lean human PCOS symptoms.

Four natural compounds were found to promote hair growth effectively.

PRGF treatment is safer and more effective for hair loss than topical minoxidil.

Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.

Cidea is essential for proper lipid storage and secretion in sebaceous glands, affecting skin and hair health.

Large prostate links to more hair loss, but age of onset doesn't affect it.

Preventing cancer involves lifestyle changes, vaccinations, early screening, and understanding cancer's molecular basis.

Post-finasteride patients show changes in gut bacteria, possibly causing various symptoms.

Zaleya pentandra extracts, especially acetone, may be useful for new medicines and food industry applications.

Higher DHT levels are linked to fewer hypogonadism symptoms in men with normal testosterone levels.

Hair loss treatments work better with lifestyle changes.

AGA is a genetic, hormonal hair loss treated with finasteride, minoxidil, and supplements, but new compounds are being developed.

Over 150 new molecules with biological activities were found in traditional herbal medicines, some with potential for new drug development.

LLLT is a safe, promising hair loss treatment, but more research needed.

Finasteride exposure affects gene expression and anogenital distance in male rat fetuses.

Purple sweet potato leaf extracts can help treat hair loss and fungal infections.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Androgenetic alopecia, or hair loss, is caused by a mix of genetics, hormones, and environment, where testosterone affects hair growth and causes hair to become smaller and grow for a shorter time.

Compound 15a was effective in inhibiting 5α-reductase.