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The document concludes that early diagnosis and treatment of PCOS in teenagers is important for managing symptoms and preventing long-term health problems.

Biologic agents can be effective for rheumatic diseases but have risks like infections and require careful monitoring and patient information.

Check serum ferritin levels and total blood count for women with diffuse hair loss.

Microneedling with topical dutasteride improves hair growth in men with hair loss and is safe to use.

Pegylated liposomal doxorubicin is as effective as conventional doxorubicin but causes fewer heart problems and side effects.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

The Rotterdam Study updated its design and objectives in 2012, providing insights into various diseases in the elderly, including skin cancer, bone health, liver disease, neurological and psychiatric conditions, and respiratory issues.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Women with PCOS have a higher risk of diabetes and heart problems, especially when they get older.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.

COVID-19 can cause skin issues like rashes and "COVID toes," and people with skin conditions should adjust their treatments if they get the virus.

Ozone reacts more with unwashed hair, producing compounds due to scalp oils, which could lower ozone exposure but increase exposure to reaction products.

An imbalanced gut and lack of biotin can cause hair loss in mice.

Doxil showed some effectiveness against advanced prostate cancer but caused severe side effects at higher doses.

A new gene, JMJD1C, may affect testosterone levels in men.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Baricitinib is effective and safe for treating severe alopecia areata.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

High doses of cyproterone acetate increase the risk of brain tumors in women, but the risk decreases after stopping the medication.

Ginseng may help treat cancer and reduce treatment side effects, but more research is needed.

Obese women with PCOS are more likely to have fatty liver disease.

Combining diphenylcyclopropenone with anthralin is more effective for hair regrowth in alopecia areata than using diphenylcyclopropenone alone, but may cause more side effects.

5-α-reductase inhibitors reduce prostate cancer risk but may cause sexual dysfunction and don't affect high-grade tumor or death rates.

No systemic treatment for alopecia areata has strong evidence of effectiveness.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Skin problems like acne, dry skin, and nail and hair changes are common in patients taking EGFR inhibitors.

5-alpha-reductase inhibitors can lower prostate cancer risk but may increase high-grade tumors and cause sexual side effects.

Brazilian women with PCOS and both menstrual irregularity and high male hormone levels have a higher chance of having metabolic syndrome.

The document concludes that managing non-classical congenital adrenal hyperplasia in females requires personalized treatment, genetic counseling, and a team of specialists.