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Hormonal therapy changes skin and hair in transgender patients, who need better researched dermatologic care.

Females have higher estrogen receptor levels in hair than males, and these levels decrease in white hair compared to black hair.

Gene mutations can cause problems in male genital development.

Aging causes hair to gray and thin, with the timing of graying varying by race, and factors like oxidative stress and genetics can lead to hair loss.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

The article concludes that hormonal therapy is an effective long-term acne treatment, even for those without hormonal imbalances.

PCOS may have evolved as an advantage in past environments with food scarcity.

Testosterone therapy can help postmenopausal women with low sexual desire but needs more safety research and should be used with estrogen therapy.

Testosterone therapy can help with androgen deficiency in women but should be used with caution and monitoring due to potential risks.

Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.

Norethisterone (jenapharm) therapy is effective for endometrial cancer.

AGA is a common hair loss affecting both genders, treated with various therapies to promote regrowth and slow thinning.

Endocrine disruptors may cause early hair loss.

Gene variant linked to prostate cancer, hormone levels, and hair loss.

Polycystic Ovary Syndrome should be seen mainly as a condition of excess male hormones, with a focus on this in its definition.

PCOS is a complex condition with major health impacts, needing more research for better diagnosis and treatment.

The enzyme steroid sulfatase is linked to breast cancer and other conditions, and inhibitors are being developed for treatment.

Coumarin derivatives show promise as anti-estrogenic agents for treating breast cancer, with some in clinical trials.

Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.

The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.

The document likely offers guidance on treating a woman's excessive hair growth, considering her symptoms and obesity.

The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone therapy for trans individuals is effective and generally safe in the short term.

Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.

Finasteride for hair loss can cause long-lasting sexual side effects like low libido and erectile dysfunction.

Hair loss needs more research for better treatments.

Lower doses of treatments for hirsutism and acne in PCOS are effective and cause fewer side effects.

Flutamide is more effective and has fewer side effects than spironolactone for treating hirsutism.