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This study found that forming spheroids using silicone micro-wells improved the viability and neural differentiation potential of human adipose-derived stem cells after thawing.

This paper discusses the role of steroid sulfatase in hormone-dependent tumors and highlights the development of potent inhibitors, noting the commencement of a phase I trial for one inhibitor in postmenopausal breast cancer patients.

This study examines the development and application of cultured models for gallbladder carcinoma and highlights innovations and challenges in constructing effective in vitro growth models for cancer research.

This article reviews organotypic skin culture systems and their applications in dermatological research, highlighting their ability to model human epidermal conditions in vitro, but it reports no new clinical results.

This study found that using three-dimensional cell culture with Matrigel enhances the biological function and stemness of stem cells, leading to improved soft tissue repair and healing by activating the host microenvironment and autologous stem cells.

This review highlights how organoid technology is transforming precision medicine by summarizing its development and applications in modeling diseases, testing drug efficacy, and tailoring patient-specific treatments, despite current challenges in standardization and ethical considerations.

In this perspective, recent advances in regenerative medicine, including bioartificial substitutes and engineered in vitro platforms, are reviewed for their potential to restore human hair follicles, highlighting new technologies like 3D printing, hair-on-a-chip models, and stem cell-derived organoids.

This review discusses the biology and signaling mechanisms of dermal papilla cells in hair follicle growth and reports no new clinical results; the authors emphasize the importance of optimizing culture conditions for hair restoration.

This review evaluates in vitro hair follicle models, techniques, and challenges without reporting new clinical results, emphasizing their future potential in hair transplantation.

This review summarizes advancements in biomedical engineering for hair follicle regeneration, highlighting strategies like cell transplantation and tissue engineering to reconstruct hair follicles, and discusses both their technical limitations and potential future innovations in regenerative medicine.

This review discusses various tissue engineering approaches for hair follicle regeneration and biomaterials used, emphasizing its potential despite current clinical challenges.

This review outlines the potential of using human pluripotent stem cells for hair follicle bioengineering, detailing current HF morphogenesis and cycling knowledge, various cell sources, and strategies using iPSCs, while discussing the challenges and prospects for therapeutic use in addressing hair loss.

This study demonstrates the use of microscopy-guided laser ablation to create a highly structured 3D hydrogel-based organotypic skin model with folliculoid structures, potentially useful for studying hair follicle development or bioactive substance screening.

This study suggests the possibility of regenerating hair follicle structures in vitro using hiPSC-derived cell composites, which might reduce reliance on human tissue-derived cells for hair bioengineering.

This study suggests that bio-nanovesicles, such as exosomes and microvesicles, may enhance skin and hair follicle regeneration by modulating key signaling pathways, potentially overcoming the limitations of conventional treatments for alopecia and chronic skin diseases.

This study found that 5% activated platelet-rich plasma significantly improved cell proliferation and hair-inductive ability of dermal papilla cells in vitro, and promoted hair follicle formation in mice.

This review found significant progress in 3D bioprinting for surgery, noting advances in creating complex tissue constructs, while highlighting ongoing challenges like vascularization and integration with host tissue, emphasizing the need for further research and regulatory development.

This review highlights that incorporating nanomaterials into scaffolds can significantly enhance angiogenesis in tissue regeneration by simulating extracellular matrix structures and effectively delivering angiogenesis-related factors, offering promising designs for vascularization and therapeutic applications.

This review highlighted that in an in vitro setting, 3D spheroid cultures of fish cells offer a promising alternative to traditional monolayer cultures, potentially advancing research in eco-toxicology, immunology, drug screening, and more by better mimicking in vivo conditions.

This study found that suspension culture was more effective than hydrogel-based systems for maintaining spheroid morphology and differentiation of human iPSC-derived definitive endoderm cells.

This review explores biomaterials in non-viral gene delivery systems and highlights the need for more research to better understand how various parameters affect gene delivery processes, without reporting new experimental results.

This review discusses the potential of microneedles to enhance transdermal drug delivery by expanding the range of deliverable drugs, highlighting fabrication methods, material choices, and applications, but notes existing challenges with sustained delivery, cost-effectiveness, and large-scale production.

This article discusses photobiomodulation as a potential adjunct to hair follicle organoid culture for androgenic alopecia, reporting no new results and suggesting further study is needed.

This review highlights the use of droplet microfluidics in microgel fabrication, emphasizing its ability to control microgel properties and discussing applications in areas like drug delivery and tissue engineering, as well as addressing current challenges and future research directions.

In this study, researchers developed a microfluidics-based method for creating uniform, size-controlled stem cell spheroids that enhance osteogenic differentiation when encapsulated in alginate-RGD microgels.

This study found that cultured mouse dermal papilla (mDP) cells can induce hair follicle neogenesis in de novo regenerated skin tissues grafted onto mice.

This review discusses recent advances in hair regeneration therapies, highlighting the potential of nanotechnology and pluripotent stem cells, and reports no new results, emphasizing the need for further research.

In this study, cell membrane remodeling with a thermoresponsive boronic acid copolymer was shown to rapidly form spheroids from cancer or cardiac cell lines under standard conditions, promising advances in tissue engineering.

This review discusses the role of epidermal and other adult stem cells in skin repair, focusing on their potential therapeutic applications for non-healing wounds and other skin disorders, but reports no new research results.

This study found that using layer-by-layer encapsulation techniques on dermal papilla cells can support their function and may help treat hair loss when used in conjunction with freshly isolated epidermal cells.