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The article suggests that targeting specific immune pathways could help control and treat the skin disease hidradenitis suppurativa.

AP-2α and AP-2β proteins are essential for healthy adult skin and hair.

T cells and bacteria in the gut and skin help maintain health and protect against disease.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Hair loss may increase heart disease risk.

Phospholipase A2 enzymes play key roles in skin health and disease.

The study found key factors in the cause of hidradenitis suppurativa, its link to other diseases, and identified existing drugs that could potentially treat it.

Hataedock treatment improved skin health and reduced atopic dermatitis symptoms by enhancing the skin barrier and reducing inflammation.

CBD may improve skin and hair health, but its effective use and safety need more research.

DHEA may help with sexual function when used intravaginally by menopausal women but is similar to hormone therapy in other aspects and might cause more side effects like acne and hair loss.

The document concludes that research on sulfatase inhibitors should continue due to their potential in treating various diseases, despite some clinical trial failures.

The skin microbiome helps heal wounds and can be targeted to improve healing.

There is no gold standard treatment for hidradenitis suppurativa due to insufficient evidence.

New wound healing method using nanoparticles in a gel speeds up healing and reduces infection and inflammation.

Glioblastoma cells can make androgens, which might help the tumor grow.

Spironolactone is effective and safe for treating hair loss, excessive hair growth, and acne.

The research found that polycystic ovary syndrome (PCOS) has two distinct types, with one having more severe hormone and insulin issues.

Men with baldness have higher levels of specific proteins, suggesting local hormone production may play a role in hair loss.

ERβ has potential in treating prostate cancer and neurodegenerative diseases, but human studies are needed before clinical use.

High levels of male hormones, insulin resistance, and obesity are closely linked and worsen polycystic ovary syndrome, but more research is needed to improve treatments.

The document concludes that Catalyst software is effective for drug design, identifying potent compounds for various medical conditions.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

Spironolactone most effective for hirsutism, but has side effects.

Certain genetic variations in the AR and ERβ genes can affect androgen levels in women.

Polycystic Ovary Syndrome is linked to higher risk of hypertension and heart disease.

Quercetin may help with PCOS symptoms, but more research is needed.

Ketoconazole cream is effective for skin conditions like seborrheic dermatitis and may help with hair loss and other skin issues, with generally mild side effects.

Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.

Certain HSD3B1 gene types are linked to worse prostate cancer outcomes and affect treatment response and other health conditions.

Putting ketoconazole on the skin can help mice grow hair.