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    Did you mean 17β-Hydroxysteroid Dehydrogenase?
    Glossary 17β-Hydroxysteroid Dehydrogenase

    enzyme that converts weaker sex hormones into more potent ones

    17β-Hydroxysteroid Dehydrogenase (17β-HSD) is an enzyme that plays a crucial role in the metabolism of steroids, including the conversion of weaker sex hormones into more potent ones. For example, it can convert androstenedione to testosterone and estrone to estradiol, which are important processes in regulating various physiological functions such as reproduction, hair growth, and overall hormonal balance.

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    1. 17 beta-hydroxysteroid dehydrogenase 3 deficiency in the Mediterranean population. PubMed · 2006 · 46 citations
    2. 17-Beta-Hydroxy-Steroid-Dehydrogenases in Hair Follicles of Normal and Bald Scalp: A Histochemical Study Journal of Investigative Dermatology · 1973 · 10 citations
    3. Expression of mRNA for androgen receptor, 5alpha-reductase and 17beta-hydroxysteroid dehydrogenase in human dermal papilla cells 1999 · 63 citations
    4. Roles of Type 10 17beta-Hydroxysteroid Dehydrogenase in Intracrinology and Metabolism of Isoleucine and Fatty Acids Endocrine, metabolic & immune disorders. Drug targets · 2006 · 26 citations
    5. 17beta Hydroxysteroid Dehydrogenase Type 3 Inhibitors 2004
    6. MALE PSEUDOHERMAPHRODITISM DUE TO 17β-HYDROXYSTEROID DEHYDROGENASE DEFICIENCY: STUDIES ON THE NATURAL HISTORY OF THE DEFECT AND EFFECT OF ANDROGENS ON GENDER ROLE Elsevier eBooks · 1983
    7. Cutaneous hydroxystereoid dehydrogenases and rat-hair-cycle Archives of Dermatological Research · 1975 · 2 citations
    8. 5α-Reductase activity in the human hair follicle concentrates in the dermal papilla Archives of Dermatological Research · 1998 · 41 citations
    9. Current evidence for the involvement of sex steroid receptors and sex hormones in benign prostatic hyperplasia Research and Reports in Urology · 2019 · 26 citations
    10. Idiopathic hirsutism: Is it really idiopathic or is it misnomer? World Journal of Clinical Cases · 2023 · 11 citations
    11. The Use of Trilostane for the Treatment of Alopecia X in Alaskan Malamutes 2005 · 15 citations
    12. Apparent Cortisone Reductase Deficiency: A Rare Cause of Hyperandrogenemia and Hypercortisolism Hormone Research in Paediatrics · 2000 · 41 citations
    13. Sebocytes are the Key Regulators of Androgen Homeostasis in Human Skin 2001 · 196 citations
    14. Virilism and Ectopic Expression of HSD17B5 in Mature Cystic Teratoma Tohoku journal of experimental medicine · 2017 · 1 citations
    15. 5α-Reductase and 11β-Hydroxysteroid Dehydrogenase Activity in Prepubertal Hispanic Girls with Premature Adrenarche The Journal of Clinical Endocrinology & Metabolism · 2002 · 11 citations
    16. Identifying 17-β-HSD3 Deficiency in Patients with Karyotype 46,XY Misdiagnosed with Androgen Insensitivity Syndrome: A Pediatric Case Report American Journal of Case Reports · 2025
    17. Influence of estrogens on the androgen metabolism in different subunits of human hair follicles. PubMed · 2001 · 41 citations
    18. Natural potent androgens: Lessons from human genetic models Baillière s Clinical Endocrinology and Metabolism · 1998 · 60 citations
    19. Oxidative Activity of the Type 2 Isozyme of 17β-Hydroxysteroid Dehydrogenase (17β-HSD) Predominates in Human Sebaceous Glands Journal of Investigative Dermatology · 1998 · 45 citations
    20. Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels Recent Patents on Endocrine, Metabolic & Immune Drug Discovery · 2007 · 20 citations
    21. Steroid 17β-hydroxysteroid dehydrogenase deficiency in man: An inherited form of male pseudohermaphroditism The Journal of Steroid Biochemistry and Molecular Biology · 1992 · 46 citations
    22. A Platform for Determining Medicinal Plants with Targeted 17β-Hydroxysteroid Dehydrogenase Modulation for Possible Hair Loss Prevention Cosmetics · 2024
    23. An Adult With Hair Loss! a Rare Case of Non-Classical 3β Hydroxysteroid Dehydrogenase (3β HSD) Deficiency Journal of the Endocrine Society · 2021
    24. Delayed Diagnosis of Congenital Adrenal Hyperplasia Due to 3β-Hydroxysteroid Dehydrogenase Type 2 Deficiency JCEM Case Reports · 2025
    25. Urinary 5-ene-steroid excretion in non-classical congenital adrenal hyperplasia due to 3β-hydroxysteroid dehydrogenase deficiency (NC-3BHSD) Journal of Steroid Biochemistry · 1990 · 3 citations
    26. Enzymology of the hair follicle. PubMed · 2001 · 31 citations
    27. Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome The Journal of Clinical Endocrinology & Metabolism · 2016 · 40 citations
    28. 46, XY Disorder of Sexual Development with Ambiguous Female External Genitalia: A Case Report Journal of Advances in Internal Medicine · 2021
    29. Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome Nature Clinical Practice Endocrinology & Metabolism · 2005 · 69 citations
    30. Gene expression of type 2 17β hydroxysteroid dehydrogenase in scalp hairs of hirsute women Steroids · 2003 · 28 citations