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    Did you mean 17α-estradiol?
    Glossary 17α-estradiol

    stereoisomer of estradiol studied for treating hair loss

    17α-estradiol, also known as 17-alpha-estradiol, is a stereoisomer of the hormone estradiol. Unlike its more common counterpart, 17β-estradiol, 17α-estradiol has weaker estrogenic activity but has been studied for its potential benefits in treating conditions like androgenic alopecia (hair loss) due to its ability to modulate androgen metabolism.

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    Research 30 of 475

    1. Testosterone modulation of seizure susceptibility is mediated by neurosteroids 3α-androstanediol and 17β-estradiol Neuroscience · 2004 · 136 citations
    2. 17β-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-α pathway 2000 · 71 citations
    3. Determination of estrone and 17β-estradiol in human hair by gas chromatography–mass spectrometry The Analyst · 2000 · 64 citations
    4. 17β-estradiol Inhibits the Production of RANTES in Human Keratinocytes Journal of Investigative Dermatology · 2003 · 56 citations
    5. 17β-Estradiol Inhibits Wound Healing in Male Mice via Estrogen Receptor-α American Journal Of Pathology · 2010 · 38 citations
    6. 17β-Estradiol Enhances Vascular Endothelial Growth Factor Production and Dihydrotestosterone Antagonizes the Enhancement via the Regulation of Adenylate Cyclase in Differentiated THP-1 Cells 2002 · 18 citations
    7. 17β-Estradiol Increases APE1/Ref-1 Secretion in Vascular Endothelial Cells and Ovariectomized Mice: Involvement of Calcium-Dependent Exosome Pathway Biomedicines · 2021 · 9 citations
    8. Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells International Journal of Molecular Sciences · 2022 · 8 citations
    9. 17β-Estradiol Enhances Contact Hypersensitivity in a Hair Cycle-Dependent Manner and Retards Thymic Atrophy with Age Immunopharmacology and Immunotoxicology · 2007 · 5 citations
    10. Locally Synthetized 17-β-Estradiol Reverses Amyloid-β-42-Induced Hippocampal Long-Term Potentiation Deficits International journal of molecular sciences · 2024
    11. Peripubertal Testosterone, 17β-Estradiol and Progesterone Concentrations in Hair and Nails in Dobermann Dogs Animals · 2023
    12. 1370 17β-estradiol may control human HF growth also via up-regulating the expression of cannabinoid receptor type1 expression 2018
    13. Effects of 17-β-Estradiol and ICI 182 780 on Hair Growth in Various Strains of Mice Journal of Investigative Dermatology Symposium Proceedings · 1999 · 32 citations
    14. Modulation of Chemotherapy-Induced Human Hair Follicle Damage by 17-β Estradiol and Prednisolone: Potential Stimulators of Normal Hair Regrowth by “Dystrophic Catagen” Promotion? Journal of Investigative Dermatology · 2008 · 18 citations
    15. Achieving Physiologic 17-ẞ-Estradiol Levels in Transgender Females on Estradiol Transdermal Patches and Optimal Dosing Journal of the Endocrine Society · 2021
    16. Health benefits attributed to 17α-estradiol, a lifespan-extending compound, are mediated through estrogen receptor α bioRxiv (Cold Spring Harbor Laboratory) · 2020
    17. Efficacy of Topical Finasteride 0.5% vs 17α-Estradiol 0.05% in the Treatment of Postmenopausal Female Pattern Hair Loss: A Retrospective, Single-Blind Study of 119 Patients Dermatology practical & conceptual · 2020 · 4 citations
    18. 17α‐estradiol induces aromatase activity in intact human anagen hair follicles <i>ex vivo</i> Experimental Dermatology · 2002 · 94 citations
    19. Reduced estradiol synthesis by letrozole, an aromatase inhibitor, is protective against development of pentylenetetrazole-induced kindling in mice Neurochemistry International · 2015 · 14 citations
    20. Hormonal Treatment of Transgender Women with Oral Estradiol Transgender health · 2018 · 37 citations
    21. Effects of Estradiol on Culture in vitro of Cashmere Goat Primary Hair Follicles Anhui nongye kexue · 2009
    22. Effects of Estradiol on Cashmere Goat Primary Hair Follicles Cultured in vitro 农业科学与技术(英文版) · 2008
    23. Assessment of Circulating Sex Steroid Levels in Prepubertal and Pubertal Boys and Girls by a Novel Ultrasensitive Gas Chromatography-Tandem Mass Spectrometry Method The Journal of Clinical Endocrinology & Metabolism · 2009 · 169 citations
    24. Gender Differences in Mouse Skin Morphology and Specific Effects of Sex Steroids and Dehydroepiandrosterone Journal of Investigative Dermatology · 2005 · 168 citations
    25. The role of estrogen in cutaneous ageing and repair Maturitas · 2017 · 158 citations
    26. Skeletal Site-Dependent Expression of the Androgen Receptor in Human Osteoblastic Cell Populations Calcified Tissue International · 1997 · 123 citations
    27. Estrogen Receptor α, but not Estrogen Receptor β, is Involved in the Regulation of the Hair Follicle Cycling as well as the Thickness of Epidermis in Male Mice Journal of Investigative Dermatology · 2002 · 72 citations
    28. Neo-synthesis of estrogenic or androgenic neurosteroids determine whether long-term potentiation or depression is induced in hippocampus of male rat Frontiers in Cellular Neuroscience · 2015 · 32 citations
    29. Synaptic Long-Term Potentiation and Depression in the Rat Medial Vestibular Nuclei Depend on Neural Activation of Estrogenic and Androgenic Signals PLoS ONE · 2013 · 25 citations
    30. Effects of sex steroid hormones and their metabolites on neuronal injury caused by oxygen-glucose deprivation/reoxygenation in organotypic hippocampal slice cultures Steroids · 2016 · 24 citations